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Accrued Wind-Down Expenses - Summary of Wind-Down Expenses (Detail) - USD ($)	3 Months Ended	9 Months Ended
	Sep. 30, 2016	Sep. 30, 2016
Restructuring Cost and Reserve [Line Items]
Total wind-down expense	$ 2,694	$ 3,806,142
Employee Related [Member]
Restructuring Cost and Reserve [Line Items]
Total wind-down expense		3,135,182
External Services [Member]
Restructuring Cost and Reserve [Line Items]
Total wind-down expense		319,953
Legal [Member]
Restructuring Cost and Reserve [Line Items]
Total wind-down expense		286,134
Facilities Related [Member]
Restructuring Cost and Reserve [Line Items]
Total wind-down expense		(590,505)
Clinical Trials Closeout [Member]
Restructuring Cost and Reserve [Line Items]
Total wind-down expense		430,834
Other [Member]
Restructuring Cost and Reserve [Line Items]
Total wind-down expense		$ 224,544