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Condensed Consolidated Statements of Cash Flows (Unaudited) - USD ($)
 9 Months Ended
Sep. 30, 2016
Sep. 30, 2015
Cash flows from operating activities:    
Net loss $ (11,293,817) $ (27,455,062)
Adjustments to reconcile net loss to net cash used in operating activities:    
Depreciation and amortization 457,616 840,533
Stock-based compensation 743,174 4,086,710
Amortization of debt discount and issuance costs 6,331 98,988
Gain on disposal of fixed assets (18,888) (168,898)
Write-down of fixed assets 3,332,736  
Change in fair value of warrant liability (1,596,554) (1,068,626)
Conversion of CIRM loan to grant revenue (8,916,641)  
Gain on extinguishment of CIRM loan (242,931)  
Discount received on final settlement of vendor invoices (1,875,701)  
Changes in operating assets and liabilities:    
Trade receivables   152,877
Other receivables 29,459 113,746
Prepaid and other current assets 570,230 213,761
Other assets 40,000  
Accounts payable and accrued expenses (4,345,253) (511,188)
Accrued wind-down expense (1,319,863)  
Deferred revenue (12,619) (12,619)
Deferred rent (44,977) (40,477)
Net cash used in operating activities (24,487,698) (23,750,255)
Cash flows from investing activities:    
Purchases of property, plant and equipment (15,434) (1,005,273)
Proceeds from sale of property, plant and equipment 1,468,888 168,713
Net cash provided by (used in) investing activities 1,453,454 (836,560)
Cash flows from financing activities:    
Proceeds from the issuance of common stock, net of issuance costs 7,259,613 24,942,963
Proceeds from exercise of warrants, net 3,044,035  
Release of restricted cash 2,422,500  
Payments related to net share issuance of stock based awards (289,969) (392,587)
Repayment of capital lease obligations (11,030) (17,764)
Proceeds from loan payable 2,000,000  
Repayment of loan payable (1,422,495) (3,730,168)
Net cash provided by financing activities 13,002,654 20,802,444
Decrease in cash and cash equivalents (10,031,590) (3,784,371)
Effects of foreign exchange rate changes on cash (357) (17,969)
Cash and cash equivalents, beginning of period 12,110,565 24,987,603
Cash and cash equivalents, end of period 2,078,618 21,185,263
Supplemental disclosure of cash flow information:    
Interest paid $ 40,529 191,895
Supplemental schedule of non-cash investing and financing activities:    
Equipment acquired under a capital lease [1]   $ 28,882
[1] Represents the present value of future minimum capital lease payment for equipment leased