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Derivative Warrant Liabilities - Schedule of Outstanding Warrants Liabilities (Details) - $ / shares
 12 Months Ended
Dec. 31, 2016
Nov. 28, 2016
Series A (2011) [Member]    
Number of Warrant Outstanding, shares   64,230
Warrant Exercise Price, Per Share $ 151.20  
Number of Warrant Exercisable, shares  
Warrant Exercisable Through, date Dec. 31, 2016  
Series A (2013) [Member]    
Number of Warrant Outstanding, shares   57,814
Warrant Exercise Price, Per Share $ 194.40  
Number of Warrant Exercisable, shares 57,814  
Warrant Exercisable Through, date Oct. 31, 2018  
Series A (2013) [Member]    
Number of Warrant Outstanding, shares   2,718
Warrant Exercise Price, Per Share $ 183.60  
Number of Warrant Exercisable, shares 2,718  
Warrant Exercisable Through, date Apr. 30, 2023  
Series A (2015) [Member]    
Number of Warrant Outstanding, shares   10,139
Warrant Exercise Price, Per Share $ 91.80  
Number of Warrant Exercisable, shares 10,139  
Warrant Exercisable Through, date Apr. 30, 2020  
Series A (2016) [Member]    
Number of Warrant Outstanding, shares [1]   10,047
Warrant Exercise Price, Per Share [1] $ 2.70  
Number of Warrant Exercisable, shares [1] 10,047  
Warrant Exercisable Through, date [1] Mar. 31, 2018  
Series B (2016) [Member]    
Number of Warrant Outstanding, shares [1]   41,116
Warrant Exercise Price, Per Share [1] $ 2.70  
Number of Warrant Exercisable, shares [1] 41,116  
Warrant Exercisable Through, date [1] Mar. 31, 2022  
[1] These warrants contain a full ratchet anti-dilution price protection so that, in most situations upon the issuance of any common stock or securities convertible into common stock at a price below the then-existing exercise price of the outstanding warrants, the warrant exercise price will be reset to the lower common stock sales price.