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Derivative Warrant Liabilities - Schedule of Outstanding Warrants Liabilities (Details) - USD ($)
 3 Months Ended
Mar. 31, 2017
Dec. 31, 2016
Series A (2011) [Member]    
Number of Warrant Outstanding, shares 64,230
Warrant Exercise Price, Per Share $ 151.20  
Warrant Exercisable  
Number of Warrant Exercisable, Period December 2016  
Series A (2013) [Member]    
Number of Warrant Outstanding, shares 57,814 57,814
Warrant Exercise Price, Per Share $ 194.40  
Warrant Exercisable $ 57,814  
Number of Warrant Exercisable, Period October 2018  
Series A (2013) [Member]    
Number of Warrant Outstanding, shares 2,718 2,718
Warrant Exercise Price, Per Share $ 183.60  
Warrant Exercisable $ 2,718  
Number of Warrant Exercisable, Period April 2023  
Series A (2015) [Member]    
Number of Warrant Outstanding, shares 10,139 10,139
Warrant Exercise Price, Per Share $ 91.80  
Warrant Exercisable $ 10,139  
Number of Warrant Exercisable, Period April 2020  
Series A (2016) [Member]    
Number of Warrant Outstanding, shares [1],[2] 9,279 10,047
Warrant Exercise Price, Per Share $ 2.70 [1],[2] $ 2.70
Warrant Exercisable $ 10,047  
Number of Warrant Exercisable, Period March 2018  
Series B (2016) [Member]    
Number of Warrant Outstanding, shares [1] 41,116 [2] 41,116
Warrant Exercise Price, Per Share $ 2.70 [1],[2] $ 2.70
Warrant Exercisable $ 41,116  
Number of Warrant Exercisable, Period March 2022  
[1] On March 2017, an institutional holder executed a cashless exercise of 768 warrants and 359 shares of common stock were issued in connection therewith.
[2] These warrants contain a full ratchet anti-dilution price protection so that, in most situations upon the issuance of any common stock or securities convertible into common stock at a price below the then-existing exercise price of the outstanding warrants, the warrant exercise price will be reset to the lower common stock sales price.