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Derivative Warrant Liabilities - Schedule of Outstanding Warrants Liabilities (Details) - $ / shares
 12 Months Ended
Dec. 31, 2017
Dec. 31, 2016
Series A (2011) [Member]    
Number of Warrant Outstanding, shares 64,230
Warrant Exercise Price, Per Share $ 151.20  
Warrant Exercisable  
Number of Warrant Exercisable, Period December 2016  
Series A (2013) [Member]    
Number of Warrant Outstanding, shares 57,814 57,814
Warrant Exercise Price, Per Share $ 194.40  
Warrant Exercisable 57,814  
Number of Warrant Exercisable, Period October 2018  
Series A (2013) [Member]    
Number of Warrant Outstanding, shares 2,718 2,718
Warrant Exercise Price, Per Share $ 183.60  
Warrant Exercisable 2,718  
Number of Warrant Exercisable, Period April 2023  
Series A (2015) [Member]    
Number of Warrant Outstanding, shares 10,139 10,139
Warrant Exercise Price, Per Share $ 91.80  
Warrant Exercisable 10,139  
Number of Warrant Exercisable, Period April 2020  
Series A (2016) [Member]    
Number of Warrant Outstanding, shares [1] 9,279 10,047
Warrant Exercise Price, Per Share [1] $ 2.70  
Warrant Exercisable [1] 9,279  
Number of Warrant Exercisable, Period [1] March 2018  
Series B (2016) [Member]    
Number of Warrant Outstanding, shares [1] 41,116 41,116
Warrant Exercise Price, Per Share [1] $ 2.70  
Warrant Exercisable [1] 41,116  
Number of Warrant Exercisable, Period [1] March 2022  
[1] These warrants contain a full ratchet anti-dilution price protection so that, in most situations upon the issuance of any common stock or securities convertible into common stock at a price below the then-existing exercise price of the outstanding warrants, the warrant exercise price will be reset to the lower common stock sales price. As such anti-dilution price protection does not meet the specific conditions for equity classification, the Company is required to classify the fair value of these warrants as a liability, with changes in fair value to be recorded as income (loss) due to change in fair value of warrant liability. The estimated fair value of our warrant liability at December 31, 2017 and December 31, 2016, was approximately $28 and $313, respectively.