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SCHEDULE OF WARRANTS OUTSTANDING (Details)	12 Months Ended
	Dec. 31, 2021 $ / shares shares
Series A (2013) [Member]
Accumulated Other Comprehensive Income (Loss) [Line Items]
Number of outstanding warrants | shares	183
Exercise price | $ / shares	$ 2,754.00
Exercisable Through	April 9, 2023
Series B (2016) [Member]
Accumulated Other Comprehensive Income (Loss) [Line Items]
Number of outstanding warrants | shares	2,770
Exercise price | $ / shares	$ 40.50
Exercisable Through	March 14, 2022
Warrant to Underwriters 1/2019 [Member]
Accumulated Other Comprehensive Income (Loss) [Line Items]
Number of outstanding warrants | shares	8,082
Exercise price | $ / shares	$ 8.13
Exercisable Through	July 14, 2022
Warrant to Underwriters 1/2019 One [Member]
Accumulated Other Comprehensive Income (Loss) [Line Items]
Number of outstanding warrants | shares	29,500
Exercise price | $ / shares	$ 12.50
Exercisable Through	July 15, 2022
Warrant to Underwriters 12/2019 [Member]
Accumulated Other Comprehensive Income (Loss) [Line Items]
Number of outstanding warrants | shares	45,643
Exercise price | $ / shares	$ 13.13
Exercisable Through	June 25, 2023
Warrant to Underwriters 12/2019 One [Member]
Accumulated Other Comprehensive Income (Loss) [Line Items]
Number of outstanding warrants | shares	47,619
Exercise price | $ / shares	$ 13.13
Exercisable Through	June 27, 2023
Warrant to Underwriters 12/2019 Two [Member]
Accumulated Other Comprehensive Income (Loss) [Line Items]
Number of outstanding warrants | shares	45,045
Exercise price | $ / shares	$ 13.88
Exercisable Through	June 30, 2023

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+ References

Reference 1: http://www.xbrl.org/2003/role/disclosureRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 505
-SubTopic 10
-Section 50
-Paragraph 3
-URI http://asc.fasb.org/extlink&oid=123467817&loc=d3e21475-112644

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