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Significant Accounting Policies (Details) - USD ($)
$ in Thousands
3 Months Ended
Mar. 31, 2019
Jan. 01, 2019
Dec. 31, 2018
Significant Accounting Policies      
Minimum period for maturity dates for short-term investments 90 days    
Accumulated deficit $ (438,336)   $ (435,684)
Lease accounting      
Operating lease liabilities 163    
Right of use operating assets $ 63    
Lease, Practical Expedients, Package [true false] true    
Operating Lease, Liability, Current $ 100    
Operating Lease, Liability, Current, Statement of Financial Position [Extensible List] Accrued Liabilities, Current    
Operating Lease, Liability, Noncurrent $ 63    
Other Assets [Member]      
Lease accounting      
Right of use operating assets 163    
Other Current Assets [Member]      
Lease accounting      
Right of use operating assets $ 100    
Minimum      
Lease accounting      
Lessee, Operating Lease, Renewal Term 8 months 12 days    
Maximum      
Lease accounting      
Lessee, Operating Lease, Renewal Term 2 years 8 months 12 days    
Guadalupe De Los Reyes, Mexico | Option Agreement Two      
Revenue recognition      
Value of carrying value for option payment proceeds to be recognized as contract liability $ 0    
Accounting Standards Update 2016-02 | Restatement adjustment      
Lease accounting      
Operating lease liabilities   $ 186  
Right of use operating assets   $ 186