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Summary of Significant Accounting Policies - Going Concern (Details) - USD ($) |  | 3 Months Ended | 12 Months Ended | 24 Months Ended
--- | --- | --- | --- | ---
Jan. 17, 2024 | Dec. 31, 2023 | Sep. 30, 2023 | Jun. 30, 2023 | Mar. 31, 2023 | Dec. 31, 2022 | Sep. 30, 2022 | Jun. 30, 2022 | Mar. 31, 2022 | Dec. 31, 2021 | Sep. 30, 2021 | Jun. 30, 2021 | Mar. 31, 2021 | Apr. 30, 2025 | Dec. 31, 2024 | Dec. 31, 2023 | Dec. 31, 2022 | Dec. 31, 2021 | Dec. 31, 2023
Net Loss |  | $ (19,880,000) | $ (10,983,000) | $ (9,045,000) | $ (10,241,000) | $ (10,759,000) | $ (9,477,000) | $ (10,022,000) | $ (10,506,000) | $ (11,493,000) | $ (10,488,000) | $ (9,245,000) | $ (9,151,000) |  |  | $ (50,149,077) | $ (40,763,573) | $ (40,377,160) |
Net Cash Flows Used in Operating Activities |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | (26,277,824) | (24,521,082) | (26,980,411) |
Accumulated Deficit |  | $ 293,984,793 |  |  |  | $ 243,835,716 |  |  |  |  |  |  |  |  |  | 293,984,793 | 243,835,716 |  | $ 293,984,793
Net Cash Flows Used in Investing Activities |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | $ (19,280,966) | $ (21,170,816) | $ (4,852,452) |
Minimum |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Rate of issuance of stock awards or stock options due to salary reduction program |  |  |  |  |  |  |  |  |  |  |  |  |  | 150.00% |  |  |  |  |
Maximum |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Rate of issuance of stock awards or stock options due to salary reduction program |  |  |  |  |  |  |  |  |  |  |  |  |  | 200.00% |  |  |  |  |
Atomistic agreement | Atomistic SAS |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Payments for investment to Atomistic |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | $ 32,500,000
Subsequent Event |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Decrease in cash annual operating expenses | $ 8,000,000 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Percentage of decrease in cash annual operating expenses | 20.00% |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Forecast [Member] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Expected cash saving due to payroll reduction program |  |  |  |  |  |  |  |  |  |  |  |  |  | $ 1,200,000 |  |  |  |  |
Estimated total common stock value to be issued and sold |  |  |  |  |  |  |  |  |  |  |  |  |  |  | $ 50,000,000 |  |  |  |
Forecast [Member] | Minimum |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Percentage of optional salary reductions |  |  |  |  |  |  |  |  |  |  |  |  |  | 10.00% |  |  |  |  |
Forecast [Member] | Maximum |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Percentage of optional salary reductions |  |  |  |  |  |  |  |  |  |  |  |  |  | 30.00% |  |  |  |  |
Forecast [Member] | Atomistic agreement | Atomistic SAS |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Payments for investment to Atomistic |  |  |  |  |  |  |  |  |  |  |  |  |  |  | $ 5,000,000 |  |  |  |
License term |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 25 years |  |  |  |

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