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Cash and Cash Equivalents, and Investments - Schedule of Available For Sale Securities (Details) - USD ($) $ in Thousands	Mar. 31, 2021	Dec. 31, 2020
Debt Securities, Available-for-sale [Line Items]
Adjusted Cost	$ 2,559,025
Fair Value	2,558,937
Cash and cash equivalents:
Debt Securities, Available-for-sale [Line Items]
Adjusted Cost	656,169	$ 479,853
Unrealized Gain	1	0
Unrealized Loss	(2)	0
Fair Value	656,168	479,853
Short-term investments:
Debt Securities, Available-for-sale [Line Items]
Adjusted Cost	1,215,230	664,119
Unrealized Gain	1,016	1,502
Unrealized Loss	(302)	(54)
Fair Value	1,215,944	665,567
Long-term investments:
Debt Securities, Available-for-sale [Line Items]
Adjusted Cost	712,025	523,270
Unrealized Gain	122	641
Unrealized Loss	(923)	(283)
Fair Value	711,224	523,628
Commercial paper | Short-term investments:
Debt Securities, Available-for-sale [Line Items]
Adjusted Cost	605,318	204,152
Unrealized Gain	78	24
Unrealized Loss	(32)	(6)
Fair Value	605,364	204,170
Corporate debt securities | Short-term investments:
Debt Securities, Available-for-sale [Line Items]
Adjusted Cost	609,912	459,967
Unrealized Gain	938	1,478
Unrealized Loss	(270)	(48)
Fair Value	610,580	461,397
Corporate debt securities | Long-term investments:
Debt Securities, Available-for-sale [Line Items]
Adjusted Cost	673,029	484,275
Unrealized Gain	118	605
Unrealized Loss	(921)	(283)
Fair Value	672,226	484,597
Agency bonds | Long-term investments:
Debt Securities, Available-for-sale [Line Items]
Adjusted Cost	38,996	38,995
Unrealized Gain	4	36
Unrealized Loss	(2)	0
Fair Value	38,998	39,031
Cash | Cash and cash equivalents:
Debt Securities, Available-for-sale [Line Items]
Adjusted Cost	24,399	15,054
Unrealized Gain	0	0
Unrealized Loss	0	0
Fair Value	24,399	15,054
Money market funds | Cash and cash equivalents:
Debt Securities, Available-for-sale [Line Items]
Adjusted Cost	532,493	464,799
Unrealized Gain	0	0
Unrealized Loss	0	0
Fair Value	532,493	$ 464,799
Commercial paper | Cash and cash equivalents:
Debt Securities, Available-for-sale [Line Items]
Adjusted Cost	99,277
Unrealized Gain	1
Unrealized Loss	(2)
Fair Value	$ 99,276

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Amount, before tax, of unrealized gain in accumulated other comprehensive income (AOCI) on investment in debt security measured at fair value with change in fair value recognized in other comprehensive income (available-for-sale).

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