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Cash and Cash Equivalents, Investments and Fair Value Measurements - Schedule of Available For Sale Securities (Details) - USD ($) $ in Thousands	Mar. 31, 2023	Dec. 31, 2022
Debt Securities, Available-for-sale [Line Items]
Adjusted Cost	$ 1,143,095
Fair Value	1,141,636
Cash and cash equivalents:
Debt Securities, Available-for-sale [Line Items]
Adjusted Cost		$ 473,677
Unrealized Gain		0
Unrealized Loss		0
Fair Value		473,677
Cash and cash equivalents: | Level 2
Debt Securities, Available-for-sale [Line Items]
Adjusted Cost	281,340
Unrealized Gain	0
Unrealized Loss	(38)
Fair Value	281,302
Cash and cash equivalents: | Cash
Debt Securities, Available-for-sale [Line Items]
Adjusted Cost	31,393	33,532
Unrealized Gain	0	0
Unrealized Loss	0	0
Fair Value	31,393	33,532
Cash and cash equivalents: | Money market funds | Level 1
Debt Securities, Available-for-sale [Line Items]
Adjusted Cost	149,731	440,145
Unrealized Gain	0	0
Unrealized Loss	0	0
Fair Value	149,731	440,145
Cash and cash equivalents: | Commercial paper | Level 2
Debt Securities, Available-for-sale [Line Items]
Adjusted Cost	100,216
Unrealized Gain	0
Unrealized Loss	(38)
Fair Value	100,178
Short-term investments:
Debt Securities, Available-for-sale [Line Items]
Adjusted Cost		588,474
Unrealized Gain		0
Unrealized Loss		(4,501)
Fair Value		583,973
Short-term investments: | Level 2
Debt Securities, Available-for-sale [Line Items]
Adjusted Cost	280,326
Unrealized Gain	0
Unrealized Loss	(2,462)
Fair Value	277,864
Short-term investments: | Commercial paper | Level 2
Debt Securities, Available-for-sale [Line Items]
Adjusted Cost		11,744
Unrealized Gain		0
Unrealized Loss		(29)
Fair Value		11,715
Short-term investments: | Corporate debt securities | Level 2
Debt Securities, Available-for-sale [Line Items]
Adjusted Cost	214,883	491,459
Unrealized Gain	0	0
Unrealized Loss	(2,435)	(4,130)
Fair Value	212,448	487,329
Short-term investments: | U.S. treasury securities | Level 1
Debt Securities, Available-for-sale [Line Items]
Adjusted Cost	30,190	85,271
Unrealized Gain	0	0
Unrealized Loss	(21)	(342)
Fair Value	30,169	84,929
Short-term investments: | Agency bonds | Level 2
Debt Securities, Available-for-sale [Line Items]
Adjusted Cost	35,253
Unrealized Gain	0
Unrealized Loss	(6)
Fair Value	35,247
Long-term investments:
Debt Securities, Available-for-sale [Line Items]
Adjusted Cost		217,003
Unrealized Gain		280
Unrealized Loss		(1,050)
Fair Value		216,233
Long-term investments: | Level 2
Debt Securities, Available-for-sale [Line Items]
Adjusted Cost	612,822
Unrealized Gain	1,547
Unrealized Loss	(506)
Fair Value	613,863
Long-term investments: | Corporate debt securities | Level 2
Debt Securities, Available-for-sale [Line Items]
Adjusted Cost	364,729	125,735
Unrealized Gain	1,003	158
Unrealized Loss	(366)	(909)
Fair Value	365,366	124,984
Long-term investments: | U.S. treasury securities | Level 1
Debt Securities, Available-for-sale [Line Items]
Adjusted Cost	99,424	30,633
Unrealized Gain	470	122
Unrealized Loss	(54)	0
Fair Value	99,840	30,755
Long-term investments: | Agency bonds | Level 2
Debt Securities, Available-for-sale [Line Items]
Adjusted Cost	148,669	60,635
Unrealized Gain	74	0
Unrealized Loss	(86)	(141)
Fair Value	$ 148,657	$ 60,494

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