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Subsequent Events - Additional Information (Detail) - Subsequent Event [Member] | Feb. 27, 2026
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Subsequent Event [Line Items] |
Subsequent event, date | Feb. 27, 2026
Subsequent event, description | On February 27, 2026, the Board of Directors (the “Board”) of the Company appointed Richard N. Kender, a current member of the Board, to serve as Executive Chair of the Board and as Interim Chief Executive Officer of the Company, Matthew Henn, Ph.D., the Company’s Chief Scientific Officer, to the additional role of President, and Kelly Brady, M.S., the Company’s Senior Vice President, Clinical Development, to the role of Executive Vice President, Chief Operating Officer, each effective March 2, 2026 (the “Effective Date”).As a result of the appointment of Mr. Kender as Interim Chief Executive Officer and Dr. Henn as President, Thomas J. DesRosier and Marella Thorell ceased serving as Co-Chief Executive Officers and Co-Presidents of the Company as of the Effective Date. Mr. DesRosier will continue to serve as the Company’s Executive Vice President, Chief Legal Officer, and Ms. Thorell will continue to serve as the Company’s Executive Vice President, Chief Financial Officer.

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- Definition Describes the event or transaction that occurred between the balance sheet date and the date the financial statements are issued or available to be issued. + References Reference 1: http://www.xbrl.org/2003/role/disclosureRef -Topic 855 -SubTopic 10 -Name Accounting Standards Codification -Section 50 -Paragraph 2 -Subparagraph (a) -Publisher FASB -URI https://asc.fasb.org/1943274/2147483399/855-10-50-2 + Details
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- Definition Detail information of subsequent event by type. User is expected to use existing line items from elsewhere in the taxonomy as the primary line items for this disclosure, which is further associated with dimension and member elements pertaining to a subsequent event. + References Reference 1: http://www.xbrl.org/2003/role/disclosureRef -Topic 830 -SubTopic 30 -Name Accounting Standards Codification -Section 50 -Paragraph 2 -Publisher FASB -URI https://asc.fasb.org/1943274/2147481674/830-30-50-2 Reference 2: http://www.xbrl.org/2003/role/disclosureRef -Topic 855 -SubTopic 10 -Name Accounting Standards Codification -Section 50 -Paragraph 2 -Publisher FASB -URI https://asc.fasb.org/1943274/2147483399/855-10-50-2 + Details
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- Definition Date the event occurred after the balance sheet date but before financial statements are issues or available to be issued, in YYYY-MM-DD format. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Name Accounting Standards Codification -Section 50 -Paragraph 2 -Subparagraph (a) -SubTopic 10 -Topic 855 -Publisher FASB -URI https://asc.fasb.org/1943274/2147483399/855-10-50-2 + Details
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