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Discontinued Operations and TSA - Summary of Financial results of the discontinued operations (Details) - USD ($) $ in Thousands | 12 Months Ended
--- | ---
Dec. 31, 2025 | Dec. 31, 2024 | Dec. 31, 2023
Revenues [Abstract] |  |  |
Total revenue | $ 789 | $ 0 | $ 0
Operating Expenses [Abstract] |  |  |
Research and development expenses | 49,060 | 64,600 | 117,597
General and administrative expenses | 39,156 | 53,183 | 77,500
Total operating expenses | 94,760 | 121,315 | 195,097
Other Nonoperating Income (Expense) [Abstract] |  |  |
Gain on sale of VOWST business | 0 | 146,707 | 0
Interest expense | 0 | 0 | (2,468)
Net income (loss) from discontinued operations, net of tax | 0 | 125,907 | 76,406
VOWST Business [Member] |  |  |
Revenues [Abstract] |  |  |
Collaboration revenue - related party | 0 | 0 | 126,325
Total revenue | 0 |  | 126,325
Operating Expenses [Abstract] |  |  |
Research and development expenses | 0 | 5,809 | 28,263
General and administrative expenses | 0 | 4,066 | 10,244
Collaboration (profit) loss sharing - related party | 0 | (1,496) | 704
Total operating expenses | 0 | 8,379 | 39,211
(Loss) income from discontinued operations | 0 | (8,379) | 87,114
Other Nonoperating Income (Expense) [Abstract] |  |  |
Gain on sale of VOWST business | 0 | 146,707 | 0
Interest expense | 0 | (12,192) | (10,708)
Other expense | 0 | (229) | 0
Income (loss) from discontinued operations, pre-tax | 0 | 125,907 | 76,406
Income tax | 0 | 0 | 0
Net income (loss) from discontinued operations, net of tax | $ 0 | $ 125,907 | $ 76,406

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