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Segment Reporting | 12 Months Ended
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Dec. 31, 2025
Segment Reporting [Abstract] |
Segment Reporting | 14. Segment Reporting The Company's interim Chief Executive Officer, who is the Chief Operating Decision Maker ("CODM"), manages and allocates resources to the operations of the Company on a total company basis by assessing the overall level of resources available and how to best deploy these resources across functions and research and development projects that are in line with the Company's long-term company-wide strategic goals. The CODM uses the Company’s consolidated net income (loss) to monitor actual results versus the budget in assessing segment performance and the allocation of resources. The measure of segment assets is reported on the consolidated balance sheets as total assets. The Company's reportable segment net income (loss) for the years ended December 31, 2025, 2024 and 2023, consisted of the following (in thousands):
|  | Year Ended December 31, |
|  | 2025 |  |  | 2024 |  |  | 2023 |
Grant revenue |  | $ | 789 |  |  | $ | — |  |  | $ | — |
Significant segment expenses: |  |  |  |  |  |  |  |  |
Live biotherapeutics platform |  | $ | 23,573 |  |  | $ | 29,006 |  |  | $ | 43,342 |
SER-155 |  |  | 3,687 |  |  |  | 6,804 |  |  |  | 7,759 |
R&D personnel-related (including stock-based compensation) |  |  | 21,553 |  |  |  | 28,689 |  |  |  | 65,251 |
G&A personnel-related (including stock-based compensation) |  |  | 14,413 |  |  |  | 22,679 |  |  |  | 36,069 |
Professional fees |  |  | 8,991 |  |  |  | 9,805 |  |  |  | 18,784 |
Facility-related and other |  |  | 15,752 |  |  |  | 20,699 |  |  |  | 22,647 |
Gain on sale of VOWST Business |  |  | (80,685 | ) |  |  | (5,684 | ) |  |  | - |
Other segment (income) expense (1) |  |  | (12,191 | ) |  |  | 13,773 |  |  |  | (3,722 | )
Net income (loss) from continuing operations |  |  | 5,696 |  |  |  | (125,771 | ) |  |  | (190,130 | )
Net income from discontinued operations, net of tax (2) |  |  | — |  |  |  | 125,907 |  |  |  | 76,406 |
Net income (loss) |  | $ | 5,696 |  |  | $ | 136 |  |  | $ | (113,724 | )
[1] Other segment (income) expense includes manufacturing services expenses, research and development expenses on early stage programs, interest income and other (income) expense, net. [2] See Note 3, Discontinued Operations and TSA, for further details.

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- Definition The entire disclosure for reporting segments including data and tables. Reportable segments include those that meet any of the following quantitative thresholds a) it's reported revenue, including sales to external customers and intersegment sales or transfers is 10 percent or more of the combined revenue, internal and external, of all operating segments b) the absolute amount of its reported profit or loss is 10 percent or more of the greater, in absolute amount of 1) the combined reported profit of all operating segments that did not report a loss or 2) the combined reported loss of all operating segments that did report a loss c) its assets are 10 percent or more of the combined assets of all operating segments. + References Reference 1: http://www.xbrl.org/2003/role/disclosureRef -Topic 280 -SubTopic 10 -Name Accounting Standards Codification -Section 50 -Paragraph 21 -Subparagraph (b) -Publisher FASB -URI https://asc.fasb.org/1943274/2147482810/280-10-50-21 Reference 2: http://www.xbrl.org/2003/role/disclosureRef -Topic 280 -SubTopic 10 -Name 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