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v3.25.4

Nature of the Business and Basis of Presentation - Additional Information (Detail) - USD ($) $ / shares in Units, $ in Thousands |  |  |  | 9 Months Ended | 12 Months Ended
--- | --- | --- | --- | --- | ---
Jul. 01, 2025 | Jan. 15, 2025 | Aug. 05, 2024 | Sep. 30, 2024 | Dec. 31, 2025 | Dec. 31, 2024 | Dec. 31, 2023
Nature Of Business And Basis Of Presentation [Line Items] |  |  |  |  |  |  |
Entity incorporated month and year |  |  |  |  | 2010-10 |  |
Entity incorporation, state or country code |  |  |  |  | DE |  |
Payments to acquire business |  |  |  | $ 15,000 | $ 15,000 |  |
Stock issued during period, shares, new Issues |  |  |  | 714,285 | 714,285 |  |
Business combination percentage of all rent and other cost due |  |  |  |  | 80.10% |  |
Payment offset amount of employment obligation | $ 1,421 |  |  |  |  |  |
Share Price |  |  |  | $ 21 | $ 21 |  |
Milestone Prepayment |  |  | $ 60,000 |  | $ 60,000 |  |
Payment in cash for first sales milestone |  |  | 150,000 |  |  |  |
Future milestone payment |  |  | 125,000 |  |  |  |
Closing period milestone payment one |  |  | 400,000 |  |  |  |
Closing period milestone payment two |  |  | 150,000 |  |  |  |
Closing period milestone payment three |  |  | 750,000 |  |  |  |
Accumulated deficit |  |  |  |  | (972,403) | $ (978,099) |
Cash and cash equivalents |  |  |  |  | 45,766 | 30,793 |
Net loss from continuing operations |  |  |  |  | (93,971) | (121,315) | $ (195,097)
Operating cash outflows |  |  |  |  | 73,883 |  |
Installment payments |  |  |  |  | $ 75,000 |  |
Transition Services Agreement [Member] |  |  |  |  |  |  |
Nature Of Business And Basis Of Presentation [Line Items] |  |  |  |  |  |  |
Payments to acquire other productive assets | $ 25,000 | $ 50,000 |  |  |  |  |
Nestle Health Science [Member] |  |  |  |  |  |  |
Nature Of Business And Basis Of Presentation [Line Items] |  |  |  |  |  |  |
Payments to acquire business |  |  | 100,000 |  |  |  |
Satisfaction fee paid |  |  |  |  |  | $ 9,016 |
Adjusted account settlement amount |  |  | $ 17,857 |  |  |  |
Fixed interest rate |  |  | 10.00% |  |  |  |
Derivative fixed interest rate thereafter |  |  | 5.00% |  |  |  |

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