<SEC-DOCUMENT>0000814133-25-000117.txt : 20251113
<SEC-HEADER>0000814133-25-000117.hdr.sgml : 20251113
<ACCEPTANCE-DATETIME>20251113173340
ACCESSION NUMBER:		0000814133-25-000117
CONFORMED SUBMISSION TYPE:	SCHEDULE 13G/A
PUBLIC DOCUMENT COUNT:		1
FILED AS OF DATE:		20251113
DATE AS OF CHANGE:		20251113

SUBJECT COMPANY:	

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			C4 Therapeutics, Inc.
		CENTRAL INDEX KEY:			0001662579
		STANDARD INDUSTRIAL CLASSIFICATION:	BIOLOGICAL PRODUCTS (NO DIAGNOSTIC SUBSTANCES) [2836]
		ORGANIZATION NAME:           	03 Life Sciences
		EIN:				475617627
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		SCHEDULE 13G/A
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	005-91763
		FILM NUMBER:		251479957

	BUSINESS ADDRESS:	
		STREET 1:		490 ARSENAL WAY
		STREET 2:		SUITE 120
		CITY:			WATERTOWN
		STATE:			MA
		ZIP:			02472
		BUSINESS PHONE:		(617) 231-0700

	MAIL ADDRESS:	
		STREET 1:		490 ARSENAL WAY
		STREET 2:		SUITE 120
		CITY:			WATERTOWN
		STATE:			MA
		ZIP:			02472

FILED BY:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			WASATCH ADVISORS LP
		CENTRAL INDEX KEY:			0000814133
		ORGANIZATION NAME:           	
		EIN:				870319391
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		SCHEDULE 13G/A

	BUSINESS ADDRESS:	
		STREET 1:		505 WAKARA WAY
		STREET 2:		3RD FLOOR
		CITY:			SALT LAKE CITY
		STATE:			UT
		ZIP:			84108
		BUSINESS PHONE:		8015330777

	MAIL ADDRESS:	
		STREET 1:		505 WAKARA WAY
		STREET 2:		3RD FLOOR
		CITY:			SALT LAKE CITY
		STATE:			UT
		ZIP:			84108

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	WASATCH ADVISORS INC
		DATE OF NAME CHANGE:	19990611
</SEC-HEADER>
<DOCUMENT>
<TYPE>SCHEDULE 13G/A
<SEQUENCE>1
<FILENAME>primary_doc.xml
<TEXT>
<XML>
<?xml version="1.0" encoding="UTF-8"?><edgarSubmission xmlns="http://www.sec.gov/edgar/schedule13g" xmlns:com="http://www.sec.gov/edgar/common">
<headerData>
<submissionType>SCHEDULE 13G/A</submissionType> 	     <filerInfo>
<filer>
<filerCredentials>
<cik>0000814133</cik>           <ccc>XXXXXXXX</ccc>
</filerCredentials>
</filer>       <liveTestFlag>LIVE</liveTestFlag>              </filerInfo>
</headerData>   <formData>
<coverPageHeader>
<amendmentNo>5</amendmentNo> 	  <securitiesClassTitle>COM STK</securitiesClassTitle>       <eventDateRequiresFilingThisStatement>09/30/2025</eventDateRequiresFilingThisStatement>       <issuerInfo>
<issuerCik>0001662579</issuerCik>         <issuerName>C4 Therapeutics Inc</issuerName>         <issuerCusip>12529R107</issuerCusip>         <issuerPrincipalExecutiveOfficeAddress>
<com:street1>490 ARSENAL WAY, SUITE 120</com:street1>           <com:city>WATERTOWN</com:city>           <com:stateOrCountry>MA</com:stateOrCountry>           <com:zipCode>02472</com:zipCode>
</issuerPrincipalExecutiveOfficeAddress>
</issuerInfo>       <designateRulesPursuantThisScheduleFiled>
<designateRulePursuantThisScheduleFiled>Rule 13d-1(b)</designateRulePursuantThisScheduleFiled>
</designateRulesPursuantThisScheduleFiled>
</coverPageHeader>   	<coverPageHeaderReportingPersonDetails> 	         <reportingPersonName>Wasatch Advisors LP</reportingPersonName> 	  <memberGroup>a</memberGroup>       <citizenshipOrOrganization>DE</citizenshipOrOrganization>       <reportingPersonBeneficiallyOwnedNumberOfShares>
<soleVotingPower>4312039.00</soleVotingPower>         <sharedVotingPower>0.00</sharedVotingPower>         <soleDispositivePower>4852741.00</soleDispositivePower>         <sharedDispositivePower>0.00</sharedDispositivePower>
</reportingPersonBeneficiallyOwnedNumberOfShares>       <reportingPersonBeneficiallyOwnedAggregateNumberOfShares>4852741.00</reportingPersonBeneficiallyOwnedAggregateNumberOfShares>       <classPercent>6.8</classPercent>      	                              <typeOfReportingPerson>IA</typeOfReportingPerson>
</coverPageHeaderReportingPersonDetails>      	<items>
<item1>
<issuerName>C4 Therapeutics Inc</issuerName>         <issuerPrincipalExecutiveOfficeAddress>490 ARSENAL WAY, SUITE 120, WATERTOWN, MA, 02472</issuerPrincipalExecutiveOfficeAddress>
</item1>        <item2>
<filingPersonName>Wasatch Advisors LP   </filingPersonName>         <principalBusinessOfficeOrResidenceAddress>505 Wakara Way, 3rd Floor, Salt Lake City, 84108, United States</principalBusinessOfficeOrResidenceAddress>         <citizenship>DELAWARE   </citizenship>
</item2>       <item3>
<notApplicableFlag>N</notApplicableFlag>          	                                                 <typeOfPersonFiling>IA</typeOfPersonFiling>
</item3>       <item4>
<amountBeneficiallyOwned>4,852,741   </amountBeneficiallyOwned>         <classPercent>6.8</classPercent>         <numberOfSharesPersonHas>
<solePowerOrDirectToVote>4,312,039   </solePowerOrDirectToVote>           <sharedPowerOrDirectToVote>0   </sharedPowerOrDirectToVote>           <solePowerOrDirectToDispose>4,852,741   </solePowerOrDirectToDispose>           <sharedPowerOrDirectToDispose>0   </sharedPowerOrDirectToDispose>
</numberOfSharesPersonHas>
</item4>       <item5>
<notApplicableFlag>Y</notApplicableFlag>         <classOwnership5PercentOrLess>N</classOwnership5PercentOrLess>
</item5>       <item6>
<notApplicableFlag>Y</notApplicableFlag>
</item6>       <item7>
<notApplicableFlag>Y</notApplicableFlag>
</item7>       <item8>
<notApplicableFlag>Y</notApplicableFlag>
</item8>       <item9>
<notApplicableFlag>Y</notApplicableFlag>
</item9>       <item10>
<notApplicableFlag>N</notApplicableFlag> 		<certifications>By signing below I certify that, to the best of my knowledge and belief, the securities referred to above were acquired and are held in the ordinary course of business and were not acquired and are not held for the purpose of or with the effect of changing or influencing the control of the issuer of the securities and were not acquired and are not held in connection with or as a participant in any transaction having that purpose or effect, other than activities solely in connection with a nomination under ?? 240.14a-11. </certifications>
</item10>
</items> 	     <signatureInformation>
<reportingPersonName>Wasatch Advisors LP</reportingPersonName>       <signatureDetails>
<signature>Mike Yeates</signature>         <title>CEO</title>         <date>11/13/2025</date>
</signatureDetails>
</signatureInformation>
</formData>
</edgarSubmission>
</XML>
</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
