<SEC-DOCUMENT>0001104659-24-081008-index.html : 20240719
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<ACCEPTANCE-DATETIME>20240719075813
ACCESSION NUMBER:		0001104659-24-081008
CONFORMED SUBMISSION TYPE:	S-1/A
PUBLIC DOCUMENT COUNT:		30
FILED AS OF DATE:		20240719
DATE AS OF CHANGE:		20240719

FILER:

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			ACTUATE THERAPEUTICS, INC.
		CENTRAL INDEX KEY:			0001652935
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		ORGANIZATION NAME:           	03 Life Sciences
		IRS NUMBER:				473044785
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		S-1/A
		SEC ACT:		1933 Act
		SEC FILE NUMBER:	333-279734
		FILM NUMBER:		241126107

	BUSINESS ADDRESS:	
		STREET 1:		1751 RIVER RUN
		STREET 2:		SUITE 400
		CITY:			FORT WORTH
		STATE:			TX
		ZIP:			76107
		BUSINESS PHONE:		847-986-4190

	MAIL ADDRESS:	
		STREET 1:		1751 RIVER RUN
		STREET 2:		SUITE 400
		CITY:			FORT WORTH
		STATE:			TX
		ZIP:			76107

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	Apotheca Therapeutics, Inc.
		DATE OF NAME CHANGE:	20150911
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Document 1 - file: tm247121-28_s1a.htm

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Document 2 - file: tm247121d29_ex1-1.htm

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<DOCUMENT>
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<FILENAME>tm247121d29_ex5-1.htm
<DESCRIPTION>EXHIBIT 5.1
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Document 3 - file: tm247121d29_ex5-1.htm

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<DOCUMENT>
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<FILENAME>tm247121d29_ex23-1.htm
<DESCRIPTION>EXHIBIT 23.1
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Document 4 - file: tm247121d29_ex23-1.htm

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<FILENAME>tm247121d29_ex-filingfees.htm
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Document 5 - file: tm247121d29_ex-filingfees.htm

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Document 6 - file: bc_1801part-4c.jpg

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Document 7 - file: bc_1801part2-4c.jpg

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Document 8 - file: bc_1801part3b-4c.jpg

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Document 9 - file: bc_1801part3b2-4c.jpg

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Document 10 - file: bc_8moverl-4c.jpg

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Document 11 - file: bc_alive-4c.jpg

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Document 12 - file: bc_overallsurvi-4c.jpg

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Document 13 - file: bc_partial-4c.jpg

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Document 14 - file: bc_stable-4c.jpg

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Document 15 - file: fc_clinistud-4c.jpg

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Document 16 - file: fc_multimoa-4c.jpg

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Document 17 - file: fc_tcellnk-4c.jpg

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Document 18 - file: lc_elraglarit-4clr.jpg

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Document 19 - file: lc_elrainje-4c.jpg

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Document 20 - file: lc_gnp-4c.jpg

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Document 21 - file: lg_actuatetherape-4clr.jpg

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Document 22 - file: ph_mri12week-bw.jpg

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Document 23 - file: tb_adverseevent-4c.jpg

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Document 24 - file: tb_anatomical-4c.jpg

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Document 25 - file: tb_demographics-4c.jpg

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Document 26 - file: tb_elraglusib-4c.jpg

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Document 27 - file: tb_general-4c.jpg

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Document 28 - file: tb_patients-4c.jpg

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Document 29 - file: tb_route-4c.jpg

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Document 30 - file: tm247121d29_ex5-1img001.jpg

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