<SEC-DOCUMENT>0001683168-25-003707-index.html : 20250515
<SEC-HEADER>0001683168-25-003707.hdr.sgml : 20250515
<ACCEPTANCE-DATETIME>20250515161231
ACCESSION NUMBER:		0001683168-25-003707
CONFORMED SUBMISSION TYPE:	S-8
PUBLIC DOCUMENT COUNT:		7
FILED AS OF DATE:		20250515
DATE AS OF CHANGE:		20250515
EFFECTIVENESS DATE:		20250515

FILER:

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			ACTUATE THERAPEUTICS, INC.
		CENTRAL INDEX KEY:			0001652935
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		ORGANIZATION NAME:           	03 Life Sciences
		EIN:				473044785
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		S-8
		SEC ACT:		1933 Act
		SEC FILE NUMBER:	333-287317
		FILM NUMBER:		25953140

	BUSINESS ADDRESS:	
		STREET 1:		1751 RIVER RUN
		STREET 2:		SUITE 400
		CITY:			FORT WORTH
		STATE:			TX
		ZIP:			76107
		BUSINESS PHONE:		847-986-4190

	MAIL ADDRESS:	
		STREET 1:		1751 RIVER RUN
		STREET 2:		SUITE 400
		CITY:			FORT WORTH
		STATE:			TX
		ZIP:			76107

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	Apotheca Therapeutics, Inc.
		DATE OF NAME CHANGE:	20150911
</SEC-HEADER>
<DOCUMENT>
<TYPE>S-8
<SEQUENCE>1
<FILENAME>actuate_s8.htm
<DESCRIPTION>S-8
<TEXT>
Document 1 - file: actuate_s8.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-4.2
<SEQUENCE>2
<FILENAME>actuate_ex0402.htm
<DESCRIPTION>ACTUATE THERAPEUTICS, INC. 2024 EQUITY INCENTIVE PLAN
<TEXT>
Document 2 - file: actuate_ex0402.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-5.1
<SEQUENCE>3
<FILENAME>actuate_ex0501.htm
<DESCRIPTION>OPINION OF BAKER & HOSTETLER LLP
<TEXT>
Document 3 - file: actuate_ex0501.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-23.1
<SEQUENCE>4
<FILENAME>actuate_ex2301.htm
<DESCRIPTION>CONSENT OF CROWE LLP, INDEPENDENT REGISTERED PUBLIC ACCOUNTING FIRM
<TEXT>
Document 4 - file: actuate_ex2301.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-23.2
<SEQUENCE>5
<FILENAME>actuate_ex2302.htm
<DESCRIPTION>CONSENT OF KMJ CORBIN & COMPANY LLP, INDEPENDENT REGISTERED PUBLIC ACCOUNTING FIRM
<TEXT>
Document 5 - file: actuate_ex2302.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-FILING FEES
<SEQUENCE>6
<FILENAME>actuate_ex107.htm
<DESCRIPTION>CALCULATION OF FILING FEE TABLE
<TEXT>
Document 6 - file: actuate_ex107.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>7
<FILENAME>image_001.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 7 - file: image_001.jpg

</DOCUMENT>
</SEC-DOCUMENT>