<SEC-DOCUMENT>0001209191-17-047603.txt : 20170803
<SEC-HEADER>0001209191-17-047603.hdr.sgml : 20170803
<ACCEPTANCE-DATETIME>20170803210656
ACCESSION NUMBER:		0001209191-17-047603
CONFORMED SUBMISSION TYPE:	4
PUBLIC DOCUMENT COUNT:		1
CONFORMED PERIOD OF REPORT:	20170801
FILED AS OF DATE:		20170803
DATE AS OF CHANGE:		20170803

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			Bencich John
		CENTRAL INDEX KEY:			0001477056

	FILING VALUES:
		FORM TYPE:		4
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	033-80623
		FILM NUMBER:		171006710

	MAIL ADDRESS:	
		STREET 1:		2401 FOURTH AVENUE, SUITE 1050
		CITY:			SEATTLE
		STATE:			WA
		ZIP:			98121

ISSUER:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			ACHIEVE LIFE SCIENCES, INC.
		CENTRAL INDEX KEY:			0000949858
		STANDARD INDUSTRIAL CLASSIFICATION:	IN VITRO & IN VIVO DIAGNOSTIC SUBSTANCES [2835]
		IRS NUMBER:				954343413
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	BUSINESS ADDRESS:	
		STREET 1:		19820 NORTH CREEK PARKWAY
		STREET 2:		SUITE 201
		CITY:			BOTHELL
		STATE:			WA
		ZIP:			98011
		BUSINESS PHONE:		425-686-1500

	MAIL ADDRESS:	
		STREET 1:		19820 NORTH CREEK PARKWAY
		STREET 2:		SUITE 201
		CITY:			BOTHELL
		STATE:			WA
		ZIP:			98011

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	ONCOGENEX PHARMACEUTICALS, INC.
		DATE OF NAME CHANGE:	20080821

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	SONUS PHARMACEUTICALS INC
		DATE OF NAME CHANGE:	19950825
</SEC-HEADER>
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<TYPE>4
<SEQUENCE>1
<FILENAME>doc4.xml
<DESCRIPTION>FORM 4 SUBMISSION
<TEXT>
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    <periodOfReport>2017-08-01</periodOfReport>

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        <issuerCik>0000949858</issuerCik>
        <issuerName>ACHIEVE LIFE SCIENCES, INC.</issuerName>
        <issuerTradingSymbol>ACHV</issuerTradingSymbol>
    </issuer>

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            <rptOwnerCik>0001477056</rptOwnerCik>
            <rptOwnerName>Bencich John</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>19820 NORTH CREEK PARKWAY</rptOwnerStreet1>
            <rptOwnerStreet2>SUITE 201</rptOwnerStreet2>
            <rptOwnerCity>BOTHELL</rptOwnerCity>
            <rptOwnerState>WA</rptOwnerState>
            <rptOwnerZipCode>98011</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
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        <reportingOwnerRelationship>
            <isDirector>0</isDirector>
            <isOfficer>1</isOfficer>
            <isTenPercentOwner>0</isTenPercentOwner>
            <isOther>0</isOther>
            <officerTitle>CFO</officerTitle>
        </reportingOwnerRelationship>
    </reportingOwner>

    <nonDerivativeTable>
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                <directOrIndirectOwnership>
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                <value>Stock Option (right to buy)</value>
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            <securityTitle>
                <value>Restricted Stock Unit (RSU)</value>
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                <footnoteId id="F2"/>
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            <exerciseDate>
                <footnoteId id="F8"/>
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                <value>2019-05-19</value>
            </expirationDate>
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                <underlyingSecurityTitle>
                    <value>Common Stock</value>
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    </derivativeTable>

    <footnotes>
        <footnote id="F1">Reflects the 1-for-11 reverse stock split following the merger between OncoGenex Pharmaceuticals, Inc. and Achieve Life Science, Inc.</footnote>
        <footnote id="F2">Each restricted stock unit (&quot;RSU&quot;) represents a contingent right to receive one share of the issuer's common stock at settlement.</footnote>
        <footnote id="F3">Pursuant to the terms of the RSU, 25% of the total shares underlying the RSU vest annually on the later of (i) each anniversary of August 1, 2017 and (ii) the first day thereafter during which the issuer's trading window is open.</footnote>
        <footnote id="F4">The options vest as to 25% on August 1, 2018 and thereafter in monthly installments over 36 months.</footnote>
        <footnote id="F5">The options vest in monthly installments over 48 months commencing one month from August 12, 2014.</footnote>
        <footnote id="F6">Pursuant to the terms of the RSU, 25% of the total shares underlying the RSU vest annually on the later of (i) each anniversary of August 12, 2014 and (ii) the first day thereafter during which the issuer's trading window is open.</footnote>
        <footnote id="F7">The options vest in monthly installments over 48 months commencing one month from January 1, 2015</footnote>
        <footnote id="F8">Pursuant to the terms of the RSU, 25% of the total shares underlying the RSU vest annually on the later of (i) each anniversary of January 1, 2015 and (ii) the first day thereafter during which the issuer's trading window is open.</footnote>
    </footnotes>

    <remarks></remarks>

    <ownerSignature>
        <signatureName>Sandra Thomson as attorney-in-fact for John Bencich</signatureName>
        <signatureDate>2017-08-03</signatureDate>
    </ownerSignature>
</ownershipDocument>
</XML>
</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
