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v3.22.1

Consolidated Statements of Cash Flows (Unaudited) - USD ($) $ in Thousands | 3 Months Ended
--- | ---
Mar. 31, 2022 | Mar. 31, 2021
Operating Activities: |  |
Net loss | $ (7,573) | $ (7,999)
Adjustments to reconcile net loss to net cash used in operating activities: |  |
Depreciation and amortization [note 3] | 60 | 64
Stock-based compensation [note 7[c], note 7[d], note 7[e] and note 7[f]] | 823 | 542
Shares issued as settlement with trade vendor | 26 | 23
Accrued interest on SVB convertible debt [note 6] | 271 |
Changes in operating assets and liabilities: |  |
Grant receivable | 153 |
Prepaid expenses and other assets | (10) | 318
Accounts payable | (423) | 253
Accrued liabilities other | 300 | (373)
Accrued clinical liabilities | 870 | 1,677
Accrued compensation | (1,277) | (952)
Lease obligation [note 8] | 1 | (5)
Net cash used in operating activities | (6,779) | (6,452)
Financing Activities: |  |
Proceeds from exercise of warrants | 24 | 236
Proceeds from ATM, net of issuance costs | 91 |
Financing costs relating to convertible debt with SVB [note 6] | (20) |
Net cash provided by financing activities | 95 | 236
Effect of exchange rate changes on cash | (1) |
Net decrease in cash, cash equivalents and restricted cash | (6,685) | (6,216)
Cash, cash equivalents and restricted cash at beginning of the period | 43,072 | 35,903
Cash, cash equivalents and restricted cash at end of the period | $ 36,387 | $ 29,687

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