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Leases - Additional Information (Details) $ in Thousands |  | 1 Months Ended | 3 Months Ended | 9 Months Ended | 12 Months Ended
--- | --- | --- | --- | --- | ---
Dec. 28, 2022 USD ($) | Dec. 31, 2021 USD ($) ft² | Sep. 30, 2023 USD ($) | Sep. 30, 2023 USD ($) | Dec. 31, 2022 | Dec. 31, 2021 USD ($) ft²
Lessee, Lease, Description [Line Items] |  |  |  |  |  |
Lease, description |  |  |  | On March 27, 2023, the Company entered into a Second Amendment to the Harrison Lease by which the term of the Harrison Lease was extended by two months until May 2032 |  |
Operating lease cost improvements |  |  | $ 937 | $ 2,862 |  |
Reduction to the lease asset and liability |  |  |  | $ 300 |  |
Cambridge Massachusetts |  |  |  |  |  |
Lessee, Lease, Description [Line Items] |  |  |  |  |  |
Lease term |  |  |  |  | 12 months |
Lease, description |  |  |  |  | the Company leased office space in Cambridge, Massachusetts, the terms of which were month-to-month, with a 30-day written notice of cancellation |
Lease termination term |  |  |  |  | the terms of which were month-to-month, with a 30-day written notice of cancellation |
Lease, Existence of Option to Terminate [true false] |  |  |  |  | true |
Lease terimation |  |  |  |  | 2023-01 |
Newton, Massachusetts |  |  |  |  |  |
Lessee, Lease, Description [Line Items] |  |  |  |  |  |
Lease, description |  |  |  |  | The Company terminated this lease in January 2023. The Company also leased laboratory space at the University of Massachusetts, Mount Ida Campus in Newton, Massachusetts, with an initial lease term from February 1, 2022 to January 31, 2023, which the Company extended until March 2023. |
Harrison Lease |  |  |  |  |  |
Lessee, Lease, Description [Line Items] |  |  |  |  |  |
Leased space | ft² |  | 31,668 |  |  |  | 31,668
Lease commencement date |  | Dec. 29, 2022 |  |  |  |
Lease term |  | 9 years 4 months |  |  |  | 9 years 4 months
Lease, description |  |  |  | The Company’s obligation for the payment of base rent for the Premises began in May 2023, and is currently $0.2 million per month, increasing up to $0.3 million per month during the term of the Lease. The Company has one option to extend the term of the Harrison Lease, for a period of an additional five years |  |
Monthly rent expense |  | $ 200 |  |  |  |
Increase in monthly rent expense |  | $ 300 |  |  |  |
Option to extend lease |  |  |  | The Company has one option to extend the term of the Harrison Lease, for a period of an additional five years |  |
Option to extend lease term |  |  |  | true |  |
Additional period of lease |  | 5 years |  |  |  |
Fixed lease rent expense |  |  |  |  |  | $ 0
Remaining lease term |  |  | 8 years 8 months 12 days | 8 years 8 months 12 days |  |
Lease discount rate |  |  | 8.00% | 8.00% |  |
Harrison Lease | Leaseholds and Leasehold Improvements |  |  |  |  |  |
Lessee, Lease, Description [Line Items] |  |  |  |  |  |
Operating lease cost improvements | $ 2,000 |  | $ 500 | $ 3,400 |  |
Total payments to the landlord for improvements |  |  |  | $ 5,400 |  |

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