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Leases - Additional Information (Details)
$ in Thousands
 1 Months Ended 3 Months Ended 9 Months Ended 12 Months Ended
Dec. 28, 2022
USD ($)
Dec. 31, 2021
USD ($)
ft²
Sep. 30, 2023
USD ($)
Sep. 30, 2023
USD ($)
Dec. 31, 2022
Dec. 31, 2021
USD ($)
ft²
Lessee, Lease, Description [Line Items]            
Lease, description       On March 27, 2023, the Company entered into a Second Amendment to the Harrison Lease by which the term of the Harrison Lease was extended by two months until May 2032    
Operating lease cost improvements     $ 937 $ 2,862    
Reduction to the lease asset and liability       $ 300    
Cambridge Massachusetts            
Lessee, Lease, Description [Line Items]            
Lease term         12 months  
Lease, description         the Company leased office space in Cambridge, Massachusetts, the terms of which were month-to-month, with a 30-day written notice of cancellation  
Lease termination term         the terms of which were month-to-month, with a 30-day written notice of cancellation  
Lease, Existence of Option to Terminate [true false]         true  
Lease terimation         2023-01  
Newton, Massachusetts            
Lessee, Lease, Description [Line Items]            
Lease, description         The Company terminated this lease in January 2023. The Company also leased laboratory space at the University of Massachusetts, Mount Ida Campus in Newton, Massachusetts, with an initial lease term from February 1, 2022 to January 31, 2023, which the Company extended until March 2023.  
Harrison Lease            
Lessee, Lease, Description [Line Items]            
Leased space | ft²   31,668       31,668
Lease commencement date   Dec. 29, 2022        
Lease term   9 years 4 months       9 years 4 months
Lease, description       The Company’s obligation for the payment of base rent for the Premises began in May 2023, and is currently $0.2 million per month, increasing up to $0.3 million per month during the term of the Lease. The Company has one option to extend the term of the Harrison Lease, for a period of an additional five years    
Monthly rent expense   $ 200        
Increase in monthly rent expense   $ 300        
Option to extend lease       The Company has one option to extend the term of the Harrison Lease, for a period of an additional five years    
Option to extend lease term       true    
Additional period of lease   5 years        
Fixed lease rent expense           $ 0
Remaining lease term     8 years 8 months 12 days 8 years 8 months 12 days    
Lease discount rate     8.00% 8.00%    
Harrison Lease | Leaseholds and Leasehold Improvements            
Lessee, Lease, Description [Line Items]            
Operating lease cost improvements $ 2,000   $ 500 $ 3,400    
Total payments to the landlord for improvements       $ 5,400