<SEC-DOCUMENT>0001562180-15-000524.txt : 20150624
<SEC-HEADER>0001562180-15-000524.hdr.sgml : 20150624
<ACCEPTANCE-DATETIME>20150624162702
ACCESSION NUMBER:		0001562180-15-000524
CONFORMED SUBMISSION TYPE:	4
PUBLIC DOCUMENT COUNT:		1
CONFORMED PERIOD OF REPORT:	20150622
FILED AS OF DATE:		20150624
DATE AS OF CHANGE:		20150624

ISSUER:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			Tokai Pharmaceuticals Inc
		CENTRAL INDEX KEY:			0001404281
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		IRS NUMBER:				000000000
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	BUSINESS ADDRESS:	
		STREET 1:		255 STATE STREET
		STREET 2:		6TH FLOOR
		CITY:			BOSTON
		STATE:			MA
		ZIP:			02109
		BUSINESS PHONE:		617-225-4348

	MAIL ADDRESS:	
		STREET 1:		255 STATE STREET
		STREET 2:		6TH FLOOR
		CITY:			BOSTON
		STATE:			MA
		ZIP:			02109

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			McBride John S.
		CENTRAL INDEX KEY:			0001618251

	FILING VALUES:
		FORM TYPE:		4
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	001-36620
		FILM NUMBER:		15949434

	MAIL ADDRESS:	
		STREET 1:		C/O TOKAI PHARMACEUTICALS, INC.
		STREET 2:		ONE BROADWAY, 14TH FLOOR
		CITY:			CAMBRIDGE
		STATE:			MA
		ZIP:			02142
</SEC-HEADER>
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<TYPE>4
<SEQUENCE>1
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        <issuerName>Tokai Pharmaceuticals Inc</issuerName>
        <issuerTradingSymbol>TKAI</issuerTradingSymbol>
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            <rptOwnerCity>BOSTON</rptOwnerCity>
            <rptOwnerState>MA</rptOwnerState>
            <rptOwnerZipCode>02109</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
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        <reportingOwnerRelationship>
            <isDirector>false</isDirector>
            <isOfficer>true</isOfficer>
            <isTenPercentOwner>false</isTenPercentOwner>
            <isOther>false</isOther>
            <officerTitle>Chief Operating Officer</officerTitle>
            <otherText></otherText>
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        </nonDerivativeTransaction>
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    <derivativeTable>
        <derivativeTransaction>
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            </securityTitle>
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            </conversionOrExercisePrice>
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                </transactionShares>
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                </transactionPricePerShare>
                <transactionAcquiredDisposedCode>
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                </transactionAcquiredDisposedCode>
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            </expirationDate>
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                    <value>Common Stock</value>
                </underlyingSecurityTitle>
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                </underlyingSecurityShares>
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                </sharesOwnedFollowingTransaction>
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                </transactionShares>
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    <footnotes>
        <footnote id="F1">The sales reported on this Form 4 were effected pursuant to a trading plan adopted pursuant to Rule 10b5-1 under the Securities Exchange Act of 1934, as amended.</footnote>
        <footnote id="F2">The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $14.00 to $14.11 inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range.</footnote>
        <footnote id="F3">The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $14.00 to $14.02 inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range.</footnote>
        <footnote id="F4">This option vested with respect to 12.5% of the shares underlying the option on April 1, 2014 and  vests with respect to an additional 2.0833% on the first day of each month thereafter through October 1, 2017.</footnote>
    </footnotes>

    <remarks></remarks>

    <ownerSignature>
        <signatureName>/s/ Cindy Driscoll, Attorney-in-Fact</signatureName>
        <signatureDate>2015-06-24</signatureDate>
    </ownerSignature>
</ownershipDocument>
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</DOCUMENT>
</SEC-DOCUMENT>
