<SEC-DOCUMENT>0001193125-15-131300.txt : 20150415
<SEC-HEADER>0001193125-15-131300.hdr.sgml : 20150415
<ACCEPTANCE-DATETIME>20150415163034
ACCESSION NUMBER:		0001193125-15-131300
CONFORMED SUBMISSION TYPE:	8-K
PUBLIC DOCUMENT COUNT:		3
CONFORMED PERIOD OF REPORT:	20150409
ITEM INFORMATION:		Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers: Compensatory Arrangements of Certain Officers
ITEM INFORMATION:		Financial Statements and Exhibits
FILED AS OF DATE:		20150415
DATE AS OF CHANGE:		20150415

FILER:

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			Tokai Pharmaceuticals Inc
		CENTRAL INDEX KEY:			0001404281
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		IRS NUMBER:				000000000
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		8-K
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	001-36620
		FILM NUMBER:		15771976

	BUSINESS ADDRESS:	
		STREET 1:		1 Broadway
		STREET 2:		14TH FLOOR
		CITY:			Cambridge
		STATE:			MA
		ZIP:			02142
		BUSINESS PHONE:		617-225-4348

	MAIL ADDRESS:	
		STREET 1:		1 Broadway
		STREET 2:		14TH FLOOR
		CITY:			Cambridge
		STATE:			MA
		ZIP:			02142
</SEC-HEADER>
<DOCUMENT>
<TYPE>8-K
<SEQUENCE>1
<FILENAME>d910559d8k.htm
<DESCRIPTION>8-K
<TEXT>
<HTML><HEAD>
<TITLE>8-K</TITLE>
</HEAD>
 <BODY BGCOLOR="WHITE">

 <P STYLE="line-height:1.0pt;margin-top:0pt;margin-bottom:0pt;border-bottom:1px solid #000000">&nbsp;</P>
<P STYLE="line-height:3.0pt;margin-top:0pt;margin-bottom:2pt;border-bottom:1px solid #000000">&nbsp;</P> <P STYLE="margin-top:4pt; margin-bottom:0pt; font-size:18pt; font-family:Times New Roman" ALIGN="center"><B>UNITED STATES </B></P>
<P STYLE="margin-top:0pt; margin-bottom:0pt; font-size:18pt; font-family:Times New Roman" ALIGN="center"><B>SECURITIES AND EXCHANGE COMMISSION </B></P>
<P STYLE="margin-top:0pt; margin-bottom:0pt; font-size:12pt; font-family:Times New Roman" ALIGN="center"><B>WASHINGTON, D.C. 20549 </B></P> <P STYLE="font-size:12pt;margin-top:0pt;margin-bottom:0pt">&nbsp;</P><center>
<P STYLE="line-height:6.0pt;margin-top:0pt;margin-bottom:2pt;border-bottom:1.00pt solid #000000;width:21%">&nbsp;</P></center> <P STYLE="margin-top:12pt; margin-bottom:0pt; font-size:18pt; font-family:Times New Roman" ALIGN="center"><B>FORM 8-K
</B></P> <P STYLE="font-size:12pt;margin-top:0pt;margin-bottom:0pt">&nbsp;</P><center> <P STYLE="line-height:6.0pt;margin-top:0pt;margin-bottom:2pt;border-bottom:1.00pt solid #000000;width:21%">&nbsp;</P></center>
<P STYLE="margin-top:12pt; margin-bottom:0pt; font-size:12pt; font-family:Times New Roman" ALIGN="center"><B>CURRENT REPORT </B></P> <P STYLE="margin-top:0pt; margin-bottom:0pt; font-size:12pt; font-family:Times New Roman" ALIGN="center"><B>Pursuant
to Section&nbsp;13 or 15(d) </B></P> <P STYLE="margin-top:0pt; margin-bottom:0pt; font-size:12pt; font-family:Times New Roman" ALIGN="center"><B>of the Securities Exchange Act of 1934 </B></P>
<P STYLE="margin-top:12pt; margin-bottom:0pt; font-size:12pt; font-family:Times New Roman" ALIGN="center"><B>Date of Report (Date of earliest event reported): April&nbsp;9, 2015 </B></P>
<P STYLE="font-size:12pt;margin-top:0pt;margin-bottom:0pt">&nbsp;</P><center> <P STYLE="line-height:6.0pt;margin-top:0pt;margin-bottom:2pt;border-bottom:1.00pt solid #000000;width:21%">&nbsp;</P></center>
<P STYLE="margin-top:12pt; margin-bottom:0pt; font-size:24pt; font-family:Times New Roman" ALIGN="center"><B>TOKAI PHARMACEUTICALS, INC. </B></P>
<P STYLE="margin-top:0pt; margin-bottom:0pt; font-size:10pt; font-family:Times New Roman" ALIGN="center"><B>(Exact Name of Company as Specified in Charter) </B></P> <P STYLE="font-size:12pt;margin-top:0pt;margin-bottom:0pt">&nbsp;</P><center>
<P STYLE="line-height:6.0pt;margin-top:0pt;margin-bottom:2pt;border-bottom:1.00pt solid #000000;width:21%">&nbsp;</P></center> <P STYLE="font-size:12pt;margin-top:0pt;margin-bottom:0pt">&nbsp;</P>
<TABLE CELLSPACING="0" CELLPADDING="0" WIDTH="100%" BORDER="0" STYLE="BORDER-COLLAPSE:COLLAPSE; font-family:Times New Roman; font-size:8pt" ALIGN="center">


<TR>
<TD WIDTH="34%"></TD>
<TD VALIGN="bottom"></TD>
<TD WIDTH="32%"></TD>
<TD VALIGN="bottom" WIDTH="1%"></TD>
<TD WIDTH="32%"></TD></TR>


<TR STYLE="font-family:Times New Roman; font-size:10pt">
<TD VALIGN="top" ALIGN="center"><B>Delaware</B></TD>
<TD VALIGN="bottom">&nbsp;</TD>
<TD VALIGN="top" ALIGN="center"><B>001-36620</B></TD>
<TD VALIGN="bottom">&nbsp;</TD>
<TD VALIGN="top" ALIGN="center"><B>20-1000967</B></TD></TR>
<TR STYLE="font-family:Times New Roman; font-size:8pt">
<TD VALIGN="top" ALIGN="center"> <P STYLE="margin-top:0pt; margin-bottom:0pt; font-size:8pt; font-family:Times New Roman" ALIGN="center"><B>(State or Other Jurisdiction</B></P>
<P STYLE="margin-top:0pt; margin-bottom:1pt; font-size:8pt; font-family:Times New Roman" ALIGN="center"><B>of Incorporation)</B></P></TD>
<TD VALIGN="bottom">&nbsp;</TD>
<TD VALIGN="top" ALIGN="center"> <P STYLE="margin-top:0pt; margin-bottom:0pt; font-size:8pt; font-family:Times New Roman" ALIGN="center"><B>(Commission</B></P>
<P STYLE="margin-top:0pt; margin-bottom:1pt; font-size:8pt; font-family:Times New Roman" ALIGN="center"><B>File Number)</B></P></TD>
<TD VALIGN="bottom">&nbsp;</TD>
<TD VALIGN="top" ALIGN="center"> <P STYLE="margin-top:0pt; margin-bottom:0pt; font-size:8pt; font-family:Times New Roman" ALIGN="center"><B>(IRS Employer</B></P>
<P STYLE="margin-top:0pt; margin-bottom:1pt; font-size:8pt; font-family:Times New Roman" ALIGN="center"><B>Identification No.)</B></P></TD></TR>
</TABLE> <P STYLE="margin-top:12pt; margin-bottom:0pt; font-size:10pt; font-family:Times New Roman" ALIGN="center"><B>255 State Street, 6<SUP STYLE="font-size:85%; vertical-align:top">th</SUP> floor </B></P>
<P STYLE="margin-top:0pt; margin-bottom:0pt; font-size:10pt; font-family:Times New Roman" ALIGN="center"><B>Boston, Massachusetts 02109 </B></P>
<P STYLE="margin-top:0pt; margin-bottom:0pt; font-size:8pt; font-family:Times New Roman" ALIGN="center"><B>(Address of Principal Executive Offices) (Zip Code) </B></P>
<P STYLE="margin-top:12pt; margin-bottom:0pt; font-size:10pt; font-family:Times New Roman" ALIGN="center"><B>Company&#146;s telephone number, including area code: (617)&nbsp;225-4305 </B></P>
<P STYLE="margin-top:12pt; margin-bottom:0pt; font-size:10pt; font-family:Times New Roman" ALIGN="center"><B>One Broadway, 14th floor </B></P>
<P STYLE="margin-top:0pt; margin-bottom:0pt; font-size:10pt; font-family:Times New Roman" ALIGN="center"><B>Cambridge, MA 02142 </B></P>
<P STYLE="margin-top:0pt; margin-bottom:0pt; font-size:8pt; font-family:Times New Roman" ALIGN="center"><B>(Former Name or Former Address, if Changed Since Last Report) </B></P>
<P STYLE="font-size:12pt;margin-top:0pt;margin-bottom:0pt">&nbsp;</P><center> <P STYLE="line-height:6.0pt;margin-top:0pt;margin-bottom:2pt;border-bottom:1.00pt solid #000000;width:21%">&nbsp;</P></center>
<P STYLE="margin-top:12pt; margin-bottom:0pt; text-indent:4%; font-size:10pt; font-family:Times New Roman">Check the appropriate box below if the Form 8-K filing is intended to simultaneously satisfy the filing obligation of the registrant under any
of the following provisions (<I>see</I> General Instruction A.2. below): </P> <P STYLE="font-size:6pt;margin-top:0pt;margin-bottom:0pt">&nbsp;</P>
<TABLE STYLE="BORDER-COLLAPSE:COLLAPSE; font-family:Times New Roman; font-size:10pt" BORDER="0" CELLPADDING="0" CELLSPACING="0" WIDTH="100%">
<TR>
<TD WIDTH="4%" VALIGN="top" ALIGN="left"><FONT STYLE="FONT-FAMILY:WINGDINGS">&#168;</FONT></TD>
<TD ALIGN="left" VALIGN="top">Written communications pursuant to Rule 425 under the Securities Act (17 CFR 230.425) </TD></TR></TABLE> <P STYLE="font-size:6pt;margin-top:0pt;margin-bottom:0pt">&nbsp;</P>
<TABLE STYLE="BORDER-COLLAPSE:COLLAPSE; font-family:Times New Roman; font-size:10pt" BORDER="0" CELLPADDING="0" CELLSPACING="0" WIDTH="100%">
<TR>
<TD WIDTH="4%" VALIGN="top" ALIGN="left"><FONT STYLE="FONT-FAMILY:WINGDINGS">&#168;</FONT></TD>
<TD ALIGN="left" VALIGN="top">Soliciting material pursuant to Rule 14a-12 under the Exchange Act (17 CFR 240.14a-12) </TD></TR></TABLE> <P STYLE="font-size:6pt;margin-top:0pt;margin-bottom:0pt">&nbsp;</P>
<TABLE STYLE="BORDER-COLLAPSE:COLLAPSE; font-family:Times New Roman; font-size:10pt" BORDER="0" CELLPADDING="0" CELLSPACING="0" WIDTH="100%">
<TR>
<TD WIDTH="4%" VALIGN="top" ALIGN="left"><FONT STYLE="FONT-FAMILY:WINGDINGS">&#168;</FONT></TD>
<TD ALIGN="left" VALIGN="top">Pre-commencement communications pursuant to Rule 14d-2(b)&nbsp;under the Exchange Act (17 CFR 240.14d-2(b)) </TD></TR></TABLE> <P STYLE="font-size:6pt;margin-top:0pt;margin-bottom:0pt">&nbsp;</P>
<TABLE STYLE="BORDER-COLLAPSE:COLLAPSE; font-family:Times New Roman; font-size:10pt" BORDER="0" CELLPADDING="0" CELLSPACING="0" WIDTH="100%">
<TR>
<TD WIDTH="4%" VALIGN="top" ALIGN="left"><FONT STYLE="FONT-FAMILY:WINGDINGS">&#168;</FONT></TD>
<TD ALIGN="left" VALIGN="top">Pre-commencement communications pursuant to Rule 13e-4(c)&nbsp;under the Exchange Act (17 CFR 240.13e-4(c)) </TD></TR></TABLE> <P STYLE="font-size:10pt;margin-top:0pt;margin-bottom:0pt">&nbsp;</P>
<P STYLE="line-height:1.0pt;margin-top:0pt;margin-bottom:0pt;border-bottom:1px solid #000000">&nbsp;</P> <P STYLE="line-height:3.0pt;margin-top:0pt;margin-bottom:2pt;border-bottom:1px solid #000000">&nbsp;</P>

<p Style='page-break-before:always'>
<HR  SIZE="3" style="COLOR:#999999" WIDTH="100%" ALIGN="CENTER">


<TABLE STYLE="BORDER-COLLAPSE:COLLAPSE; font-family:Times New Roman; font-size:10pt" BORDER="0" CELLPADDING="0" CELLSPACING="0" WIDTH="100%">
<TR>
<TD WIDTH="10%" VALIGN="top" ALIGN="left"><B>Item&nbsp;5.02</B></TD>
<TD ALIGN="left" VALIGN="top"><B>Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers </B></TD></TR></TABLE>
<P STYLE="margin-top:6pt; margin-bottom:0pt; font-size:10pt; font-family:Times New Roman">On April&nbsp;9, 2015, Cheryl L. Cohen was elected by the Board of Directors (the &#147;Board&#148;) of Tokai Pharmaceuticals, Inc., a Delaware corporation,
(the &#147;Company&#148;) to the Board as a Class I director with a term expiring at the 2015 annual meeting of stockholders. </P> <P STYLE="margin-top:12pt; margin-bottom:0pt; font-size:10pt; font-family:Times New Roman">Ms. Cohen served as the
Chief Commercial Officer of Medivation, Inc. (&#147;Medivation&#148;) from September 2011 to July 2014, where she was responsible for the Medivation&#146;s U.S. launch of Xtandi (enzalutamide) for metastatic castration-resistant prostate cancer. At
Medivation, Ms. Cohen established and led Medivation&#146;s commercial organization and oversaw the successful launch of Xtandi, with the product achieving nearly $400M in U.S. revenues in its first full year of sales. Ms. Cohen also worked closely
on all Medivation steering committees with its commercial partner, Astellas Pharma Inc., and was involved in life cycle and strategic planning for Xtandi and in the review of new business development opportunities for Medivation. Ms. Cohen currently
serves as president of CLC Consulting, a pharmaceutical and biotechnology consulting firm specializing in new product commercialization where she also served as president from September 2008 until September 2011 when she joined Medivation. Ms.
Cohen&#146;s previous experience also includes over a decade at Johnson &amp; Johnson, including as vice president of its strategic commercial group accountable for managed markets, contracting and supply chain, Health Care Systems, Inc., and as
vice president, rheumatology franchise, of Janssen Biotech, Inc. (formerly Centocor Biotech, Inc.), where she had direct responsibility for its Remicade<SUP STYLE="font-size:85%; vertical-align:top">&reg;</SUP> U.S. rheumatoid arthritis business.
Ms. Cohen received her B.A. from Saint Joseph College. </P> <P STYLE="margin-top:12pt; margin-bottom:0pt; font-size:10pt; font-family:Times New Roman">Ms.&nbsp;Cohen has no family relationship with any of the executive officers or directors of the
Company. There are no arrangements or understandings between Ms.&nbsp;Cohen and any other person pursuant to which she was elected as a director of the Company. </P>
<P STYLE="margin-top:12pt; margin-bottom:0pt; font-size:10pt; font-family:Times New Roman">In accordance with the Company&#146;s director compensation program, Ms.&nbsp;Cohen will receive (i)&nbsp;an annual cash retainer of $35,000 for service on
the Board, which is payable quarterly in arrears. In addition, under the Company&#146;s director compensation program, upon her election as a director, Ms.&nbsp;Cohen was granted an option on April&nbsp;9, 2015 to purchase 25,000 shares of the
Company&#146;s common stock at an exercise price per share of $11.08 (the &#147;Initial Stock Option&#148;). Subject to Ms.&nbsp;Cohen&#146;s continued service on our board, this Initial Stock Option will vest with respect to one-third of the shares
underlying the option on the first anniversary of the grant date and quarterly thereafter until the third anniversary of the date of grant. Under the Company&#146;s director compensation program, Ms.&nbsp;Cohen will also receive an annual grant of
an option to purchase 12,000 shares of common stock on the date of the first meeting of the Board held after each annual meeting of stockholders (the &#147;Annual Stock Options&#148;). Subject to Ms.&nbsp;Cohen&#146;s continued service on our board,
these Annual Stock Options will vest with respect to 100% of the shares on the first anniversary of the grant date. The Initial Stock Option and Annual Stock Options will vest in full with respect to the shares then underlying such options upon the
occurrence of a change in control of the Company. </P> <P STYLE="margin-top:12pt; margin-bottom:0pt; font-size:10pt; font-family:Times New Roman">Also in connection with her election to the Board, Ms.&nbsp;Cohen will enter into the Company&#146;s
standard form of indemnification agreement, a copy of which was filed as Exhibit 10.13 to Amendment No.&nbsp;1 to the Company&#146;s Registration Statement on Form S-1 (File No.&nbsp;333-198052) filed with the SEC on September&nbsp;2, 2014. Pursuant
to the terms of this agreement, the Company may be required, among other things, to indemnify Ms.&nbsp;Cohen for some expenses, including attorneys&#146; fees, judgments, fines and settlement amounts she incurs in any action or proceeding arising
out of her service as one of our directors. </P> <P STYLE="margin-top:12pt; margin-bottom:0pt; font-size:10pt; font-family:Times New Roman">A copy of the Company&#146;s press release announcing Ms.&nbsp;Cohen&#146;s election is attached as Exhibit
99.1 to this Current Report on Form&nbsp;8-K. </P> <P STYLE="font-size:18pt;margin-top:0pt;margin-bottom:0pt">&nbsp;</P>
<TABLE STYLE="BORDER-COLLAPSE:COLLAPSE; font-family:Times New Roman; font-size:10pt" BORDER="0" CELLPADDING="0" CELLSPACING="0" WIDTH="100%">
<TR>
<TD WIDTH="10%" VALIGN="top" ALIGN="left"><B>Item&nbsp;9.01</B></TD>
<TD ALIGN="left" VALIGN="top"><B>Financial Statements and Exhibits </B></TD></TR></TABLE> <P STYLE="margin-top:6pt; margin-bottom:0pt; font-size:10pt; font-family:Times New Roman">(d) Exhibits </P>
<P STYLE="margin-top:12pt; margin-bottom:0pt; font-size:10pt; font-family:Times New Roman">The following exhibit relating to Item&nbsp;5.02 shall be deemed to be furnished, and not filed: </P>
<P STYLE="font-size:12pt;margin-top:0pt;margin-bottom:0pt">&nbsp;</P>
<TABLE CELLSPACING="0" CELLPADDING="0" WIDTH="100%" BORDER="0" STYLE="BORDER-COLLAPSE:COLLAPSE; font-family:Times New Roman; font-size:10pt" ALIGN="center">


<TR>
<TD></TD>
<TD VALIGN="bottom" WIDTH="3%"></TD>
<TD WIDTH="94%"></TD></TR>


<TR STYLE="font-family:Times New Roman; font-size:10pt">
<TD VALIGN="top" NOWRAP>99.1</TD>
<TD VALIGN="bottom"></TD>
<TD VALIGN="top">Press release issued by the Company on April 13, 2015</TD></TR>
</TABLE>

<p Style='page-break-before:always'>
<HR  SIZE="3" style="COLOR:#999999" WIDTH="100%" ALIGN="CENTER">

 <P STYLE="margin-top:0pt; margin-bottom:0pt; font-size:10pt; font-family:Times New Roman" ALIGN="center"><B>SIGNATURES </B></P>
<P STYLE="margin-top:12pt; margin-bottom:0pt; text-indent:4%; font-size:10pt; font-family:Times New Roman">Pursuant to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by
the undersigned hereunto duly authorized. </P> <P STYLE="font-size:12pt;margin-top:0pt;margin-bottom:0pt">&nbsp;</P>
<TABLE CELLSPACING="0" CELLPADDING="0" WIDTH="100%" BORDER="0" STYLE="BORDER-COLLAPSE:COLLAPSE; font-family:Times New Roman; font-size:10pt">


<TR>
<TD WIDTH="4%"></TD>
<TD VALIGN="bottom" WIDTH="1%"></TD>
<TD WIDTH="43%"></TD>
<TD VALIGN="bottom" WIDTH="1%"></TD>
<TD WIDTH="4%"></TD>
<TD VALIGN="bottom"></TD>
<TD WIDTH="2%"></TD>
<TD VALIGN="bottom" WIDTH="1%"></TD>
<TD WIDTH="43%"></TD></TR>


<TR STYLE="font-family:Times New Roman; font-size:10pt">
<TD VALIGN="top"></TD>
<TD VALIGN="bottom"></TD>
<TD VALIGN="top"></TD>
<TD VALIGN="bottom"></TD>
<TD VALIGN="top"></TD>
<TD VALIGN="bottom"></TD>
<TD VALIGN="top" COLSPAN="3"><B>TOKAI PHARMACEUTICALS, INC.</B></TD></TR>
<TR STYLE="font-size:1pt">
<TD HEIGHT="16"></TD>
<TD HEIGHT="16" COLSPAN="2"></TD>
<TD HEIGHT="16" COLSPAN="2"></TD>
<TD HEIGHT="16" COLSPAN="2"></TD>
<TD HEIGHT="16" COLSPAN="2"></TD></TR>
<TR STYLE="font-family:Times New Roman; font-size:10pt">
<TD VALIGN="top">Date:</TD>
<TD VALIGN="bottom"></TD>
<TD VALIGN="top">April 15, 2015</TD>
<TD VALIGN="bottom"></TD>
<TD VALIGN="top"></TD>
<TD VALIGN="bottom"></TD>
<TD VALIGN="top">By:</TD>
<TD VALIGN="bottom"></TD>
<TD VALIGN="top"> <P STYLE="margin-top:0pt; margin-bottom:1pt; border-bottom:1px solid #000000; font-size:10pt; font-family:Times New Roman">/s/ Lee H. Kalowski</P></TD></TR>
<TR STYLE="font-family:Times New Roman; font-size:10pt">
<TD VALIGN="top"></TD>
<TD VALIGN="bottom"></TD>
<TD VALIGN="top"></TD>
<TD VALIGN="bottom"></TD>
<TD VALIGN="top"></TD>
<TD VALIGN="bottom"></TD>
<TD VALIGN="top"></TD>
<TD VALIGN="bottom"></TD>
<TD VALIGN="top">Lee H. Kalowski</TD></TR>
<TR STYLE="font-family:Times New Roman; font-size:10pt">
<TD VALIGN="top"></TD>
<TD VALIGN="bottom"></TD>
<TD VALIGN="top"></TD>
<TD VALIGN="bottom"></TD>
<TD VALIGN="top"></TD>
<TD VALIGN="bottom"></TD>
<TD VALIGN="top"></TD>
<TD VALIGN="bottom"></TD>
<TD VALIGN="top">Chief Financial Officer</TD></TR>
</TABLE>

<p Style='page-break-before:always'>
<HR  SIZE="3" style="COLOR:#999999" WIDTH="100%" ALIGN="CENTER">

 <P STYLE="margin-top:0pt; margin-bottom:0pt; font-size:10pt; font-family:Times New Roman" ALIGN="center"><B>EXHIBIT INDEX </B></P> <P STYLE="font-size:12pt;margin-top:0pt;margin-bottom:0pt">&nbsp;</P>
<TABLE CELLSPACING="0" CELLPADDING="0" WIDTH="100%" BORDER="0" STYLE="BORDER-COLLAPSE:COLLAPSE; font-family:Times New Roman; font-size:8pt" ALIGN="center">


<TR>
<TD></TD>
<TD VALIGN="bottom" WIDTH="5%"></TD>
<TD WIDTH="92%"></TD></TR>
<TR STYLE="font-family:Times New Roman; font-size:8pt">
<TD VALIGN="bottom" ALIGN="center"><B>Exhibit<BR>Number</B></TD>
<TD VALIGN="bottom">&nbsp;&nbsp;</TD>
<TD VALIGN="bottom"><B>Description of Exhibit</B></TD></TR>


<TR STYLE="font-size:1pt">
<TD HEIGHT="8"></TD>
<TD HEIGHT="8" COLSPAN="2"></TD></TR>
<TR STYLE="font-family:Times New Roman; font-size:10pt">
<TD VALIGN="top" NOWRAP>99.1</TD>
<TD VALIGN="bottom">&nbsp;&nbsp;</TD>
<TD VALIGN="top">Press release issued by the Company on April 13, 2015</TD></TR>
</TABLE>
</BODY></HTML>
</TEXT>
</DOCUMENT>
<DOCUMENT>
<TYPE>EX-99.1
<SEQUENCE>2
<FILENAME>d910559dex991.htm
<DESCRIPTION>EX-99.1
<TEXT>
<HTML><HEAD>
<TITLE>EX-99.1</TITLE>
</HEAD>
 <BODY BGCOLOR="WHITE">

 <P STYLE="margin-top:0pt; margin-bottom:0pt; font-size:10pt; font-family:Times New Roman" ALIGN="right"><B>Exhibit 99.1 </B></P> <P STYLE="font-size:12pt;margin-top:0pt;margin-bottom:0pt">&nbsp;</P>
<P STYLE="margin-top:0pt;margin-bottom:0pt">


<IMG SRC="g910559ex99_1logo.jpg" ALT="LOGO">
 </P> <P STYLE="margin-top:12pt; margin-bottom:0pt; font-size:10pt; font-family:Times New Roman" ALIGN="center"><B>Tokai Pharmaceuticals Announces the Appointment of Cheryl Cohen, </B></P>
<P STYLE="margin-top:0pt; margin-bottom:0pt; font-size:10pt; font-family:Times New Roman" ALIGN="center"><B>Former Medivation Chief Commercial Officer, to its Board of Directors </B></P>
<P STYLE="margin-top:12pt; margin-bottom:0pt; font-size:10pt; font-family:Times New Roman">CAMBRIDGE, Mass.&#151;(BUSINESS WIRE)&#151;Apr. 13, 2015&#151;<U>Tokai Pharmaceuticals. Inc.</U> (NASDAQ: TKAI), a clinical-stage biopharmaceutical company
focused on developing novel therapies for prostate cancer and other hormonally driven diseases, today announced the appointment of Cheryl Cohen, the former Chief Commercial Officer of Medivation, Inc., to its Board of Directors. </P>
<P STYLE="margin-top:12pt; margin-bottom:0pt; font-size:10pt; font-family:Times New Roman">&#147;Cheryl brings significant commercial expertise to Tokai. As the former Chief Commercial Officer of Medivation, Cheryl led the company&#146;s highly
successful launch of Xtandi&reg; in the United States and built the company&#146;s commercial infrastructure from the ground up,&#148; said Jodie Morrison, President and Chief Executive Officer of Tokai Pharmaceuticals. &#147;As we make final
preparations to start ARMOR3-SV and begin our commercialization planning for galeterone, Cheryl&#146;s first-hand experience marketing Xtandi, as well as her broader expertise in oncology and new drug commercialization, should provide immediate
contributions to Tokai and its Board of Directors. It is my pleasure to welcome Cheryl to the Tokai Board.&#148; </P> <P STYLE="margin-top:12pt; margin-bottom:0pt; font-size:10pt; font-family:Times New Roman">&#147;It&#146;s an exciting time to be
joining the Tokai Board as galeterone advances into a registration trial in a subset of prostate cancer patients with significant unmet need,&#148; stated Ms.&nbsp;Cohen. &#147;Last year, <I>The New England Journal of Medicine</I> published the
results of the Johns Hopkins University clinical trial that demonstrated the link between AR-V7 and poor response to enzalutamide and abiraterone. I&#146;m thrilled to be able to bring my commercial experience to the Tokai board as the ARMOR3-SV
trial in AR-V7 prostate cancer is poised to begin.&#148; </P> <P STYLE="margin-top:12pt; margin-bottom:0pt; font-size:10pt; font-family:Times New Roman">Ms.&nbsp;Cohen served as the Chief Commercial Officer of Medivation, Inc., from September 2011
to July 2014, where she was responsible for the company&#146;s U.S. launch of Xtandi (enzalutamide) for metastatic castration-resistant prostate cancer. At Medivation, Ms.&nbsp;Cohen established and led the company&#146;s commercial organization and
oversaw a successful launch, with the product achieving nearly $400M in U.S. revenues in the first full year. Ms.&nbsp;Cohen also worked closely on all Medivation steering committees with its commercial partner, Astellas, and was involved in life
cycle and strategic planning for Xtandi and in the review of new business development opportunities. Ms.&nbsp;Cohen currently serves as president of CLC Consulting, a pharmaceutical and biotechnology consulting firm specializing in new product
commercialization. Ms.&nbsp;Cohen&#146;s previous experience also includes over a decade at Johnson&nbsp;&amp; Johnson, most recently as vice president, strategic commercial group, Health Care Systems, Inc., accountable for managed markets,
contracting, and supply chain, and as vice president, rheumatology franchise, Centocor, Inc., where she had direct responsibility for the $1+ billion per year Remicade U.S. rheumatoid arthritis business. She earned her B.A. from Saint Joseph
College. </P>

<p Style='page-break-before:always'>
<HR  SIZE="3" style="COLOR:#999999" WIDTH="100%" ALIGN="CENTER">

 <P STYLE="margin-top:0pt; margin-bottom:0pt; font-size:10pt; font-family:Times New Roman"><B>About Tokai Pharmaceuticals </B></P>
<P STYLE="margin-top:6pt; margin-bottom:0pt; font-size:10pt; font-family:Times New Roman">Tokai Pharmaceuticals is a biopharmaceutical company focused on developing novel therapies for prostate cancer and other hormonally-driven diseases. The
company&#146;s lead drug candidate, galeterone, is a highly selective, multi-targeted, oral small molecule drug candidate being developed for the treatment of patients with castration-resistant prostate cancer. The company&#146;s ARDA drug discovery
program is focused on the identification and evaluation of compounds that are designed to disrupt androgen receptor signaling through enhanced androgen receptor degradation and are targeted to patients with androgen receptor signaling diseases,
including prostate cancer. For more information on the company and galeterone, please visit <U>www.tokaipharma.com</U>. </P> <P STYLE="margin-top:18pt; margin-bottom:0pt; font-size:10pt; font-family:Times New Roman"><B>About the ARMOR3-SV Clinical
Trial </B></P> <P STYLE="margin-top:6pt; margin-bottom:0pt; font-size:10pt; font-family:Times New Roman">ARMOR3-SV is a randomized, open label registration Phase 3 clinical trial that will compare galeterone to Xtandi&reg; (enzalutamide) in 148
metastatic CRPC treatment-na&iuml;ve patients whose prostate tumors express the AR-V7 splice variant. The primary endpoint of the trial will be radiographic progression-free survival measured from the time of patient randomization to the time of
radiographic evidence of disease progression or time of death from any cause. The Company expects to commence the trial in the second quarter of 2015. </P>
<P STYLE="margin-top:18pt; margin-bottom:0pt; font-size:10pt; font-family:Times New Roman"><B>Forward-looking Statements </B></P> <P STYLE="margin-top:6pt; margin-bottom:0pt; font-size:10pt; font-family:Times New Roman">Any statements in this press
release about future expectations, plans and prospects for the Company, including statements about the Company&#146;s strategy, future operations, intellectual property, and other statements containing the words &#147;believes,&#148;
&#147;anticipates,&#148; &#147;plans,&#148; &#147;expects,&#148; and similar expressions, constitute forward-looking statements within the meaning of The Private Securities Litigation Reform Act of 1995. Actual results may differ materially from
those indicated by such forward-looking statements as a result of various important factors, including: whether the Company&#146;s cash resources will be sufficient to fund the Company&#146;s continuing operations for the period anticipated; whether
data from early clinical trials will be indicative of the data that will be obtained from future clinical trials; whether galeterone will advance through the clinical trial process on the anticipated timeline, including whether ARMOR3-SV will be
initiated when anticipated; whether a companion diagnostic can be developed successfully and on a timely basis; whether the results of ARMOR3-SV will warrant submission for regulatory approval of galeterone and whether such submission will receive
approval from the United States Food and Drug Administration or equivalent foreign regulatory agencies; whether, if galeterone obtains such approval, it will be successfully distributed and marketed; and other factors discussed in the &#147;Risk
Factors&#148; section of the Company&#146;s annual report on Form 10-K for the year ended December&nbsp;31, 2014. In addition, the forward-looking statements included in this press release represent the Company&#146;s views as of April&nbsp;13,
2015. The Company anticipates that subsequent events and developments may cause the Company&#146;s views to change. However, while the Company may elect to update these forward-looking statements at some point in the future, the Company specifically
disclaims any obligation to do so. These forward-looking statements should not be relied upon as representing the Company&#146;s views as of any date subsequent to April&nbsp;13, 2015. </P>

<p Style='page-break-before:always'>
<HR  SIZE="3" style="COLOR:#999999" WIDTH="100%" ALIGN="CENTER">

 <P STYLE="margin-top:0pt; margin-bottom:0pt; font-size:10pt; font-family:Times New Roman">Source: Tokai Pharmaceuticals </P>
<P STYLE="margin-top:12pt; margin-bottom:0pt; font-size:10pt; font-family:Times New Roman">Investor Contacts: </P> <P STYLE="margin-top:0pt; margin-bottom:0pt; font-size:10pt; font-family:Times New Roman">Tokai Pharmaceuticals </P>
<P STYLE="margin-top:0pt; margin-bottom:0pt; font-size:10pt; font-family:Times New Roman">Lee Kalowski, 617-225-4305 </P> <P STYLE="margin-top:0pt; margin-bottom:0pt; font-size:10pt; font-family:Times New Roman">Chief Financial Officer </P>
<P STYLE="margin-top:12pt; margin-bottom:0pt; font-size:10pt; font-family:Times New Roman">Argot Partners </P> <P STYLE="margin-top:0pt; margin-bottom:0pt; font-size:10pt; font-family:Times New Roman">David Pitts/Maeve Conneighton </P>
<P STYLE="margin-top:0pt; margin-bottom:0pt; font-size:10pt; font-family:Times New Roman">212-600-1902 </P> <P STYLE="margin-top:0pt; margin-bottom:0pt; font-size:10pt; font-family:Times New Roman"><U>david@argotpartners.com</U> </P>
<P STYLE="margin-top:0pt; margin-bottom:0pt; font-size:10pt; font-family:Times New Roman"><U>maeve@argotpartners.com</U> </P> <P STYLE="margin-top:12pt; margin-bottom:0pt; font-size:10pt; font-family:Times New Roman">Media Contact: </P>
<P STYLE="margin-top:0pt; margin-bottom:0pt; font-size:10pt; font-family:Times New Roman">Pure Communications, Inc. </P> <P STYLE="margin-top:0pt; margin-bottom:0pt; font-size:10pt; font-family:Times New Roman">Susan Heins, 864-286-9597 </P>
</BODY></HTML>
</TEXT>
</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>3
<FILENAME>g910559ex99_1logo.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
begin 644 g910559ex99_1logo.jpg
M_]C_X``02D9)1@`!``$`8`!@``#__@`?3$5!1"!496-H;F]L;V=I97,@26YC
M+B!6,2XP,0#_VP"$``@&!@<&!0@'!P<*"0@*#18.#0P,#1L3%!`6(!PB(1\<
M'QXC*#,K(R8P)AX?+#TM,#4V.3HY(BL_0SXX0S,X.3<!"0H*#0L-&@X.&C<D
M'R0W-S<W-S<W-S<W-S<W-S<W-S<W-S<W-S<W-S<W-S<W-S<W-S<W-S<W-S<W
M-S<W-S<W-__$`:(```$%`0$!`0$!```````````!`@,$!08'"`D*"P$``P$!
M`0$!`0$!`0````````$"`P0%!@<("0H+$``"`0,#`@0#!04$!````7T!`@,`
M!!$%$B$Q008346$'(G$4,H&1H0@C0K'!%5+1\"0S8G*""0H6%Q@9&B4F)R@I
M*C0U-C<X.3I#1$5&1TA)2E-455976%E:8V1E9F=H:6IS='5V=WAY>H.$A8:'
MB(F*DI.4E9:7F)F:HJ.DI::GJ*FJLK.TM;:WN+FZPL/$Q<;'R,G*TM/4U=;7
MV-G:X>+CY.7FY^CIZO'R\_3U]O?X^?H1``(!`@0$`P0'!00$``$"=P`!`@,1
M!`4A,08205$'87$3(C*!"!1"D:&QP0DC,U+P%6)RT0H6)#3A)?$7&!D:)B<H
M*2HU-C<X.3I#1$5&1TA)2E-455976%E:8V1E9F=H:6IS='5V=WAY>H*#A(6&
MAXB)BI*3E)66EYB9FJ*CI*6FIZBIJK*SM+6VM[BYNL+#Q,7&Q\C)RM+3U-76
MU]C9VN+CY.7FY^CIZO+S]/7V]_CY^O_``!$(`#D`Q0,!$0`"$0$#$0'_V@`,
M`P$``A$#$0`_`/9]=\0:?X<L/MFHRE(RVU5499V]`*TITI57:)C5K1I*\CE/
M^%O:`/\`ESU'_OVG_P`77:LMJOJOZ^1Q?VE2[/\`#_,/^%O^'_\`GSU'_OVG
M_P`73_LVKW7X_P"0?VE1[/\`#_,/^%O^'_\`GSU'_OVG_P`71_9M7NOQ_P`@
M_M*CV?X?YA_PM_P__P`^>H_]^T_^+H_LVKW7X_Y!_:5'L_P_S#_A;_A__GSU
M'_OVG_Q=']FU>Z_'_(/[2H]G^'^8#XO>'\X^QZC_`-^T_P#BZ7]FU>Z_'_(/
M[2H]G^'^9UNAZ]I_B&P%YITN^/.U@1AE/H1VKAJ4W3ERL[J=6-57B:59F@4`
M%`!0`4`%`!0`4`%`!0`4`%`!0`4`%`!0`4`>5_&8G&B#/'[[C_OBO7RR*?-?
MR_4\C,VUR?/]#RJO:/&"@`H`*`"@`H`]8^#1/V?6!GCS(SC\#7@Y@DI)^I[>
M7-V:/4:\P]4*`"@`H`*`"@`H`*`"@`H`*`"@`H`*`"@`H`*`/*_C-_S!/^V_
M_M.O9RO[?R_4\?-/L?/]#RJO8/'#Z#/TI-I;@DWHC4TGP]J6LRS1V<*;X,>8
M))%CQ_WUCTKFJUH4]7^!O3I3J:1+D?@_4GU673I6ABGCMFN2?,#J57ME<\U#
MQ,.52U^XM8>:;BS!!+N2GITKI7<YGHK#[6TN+VX2VMH6FG<X5$&23[5-22C&
M[*BKRLCU3X.JT<>M1N"K+(@8'L0#7DYEK*)[&772:/4*\H]4SVUNQ374T4R,
M+YXC,J;3C:/?I5\CY>8CG7-R=30J"PH`*`"@`H`/I0`4`%`!0!'Y\0E:+S%\
MQ5W%<\@>N*=F*ZO8J:1K%EKED;NPD+PAVCR5*\CKP:J47%V9,)J:NB_4%E:_
MO[?3+">]NF*P0*7D(&2`/84U'F?*B924%S,=97D.H6,%Y;,6AF0.A(QD'VHD
MN5V81DI*Z)Z11Y7\9O\`F"?]M_\`VG7LY7]OY?J>/FGV/G^AY57L'CG1>!!;
MGQKIBW$;2`R80`@`-@X)]1[5Q8V_LG8[,$DZJ3-5=-TB_P!:\5:E/;3/:Z:&
MD\CSL&1]QS\P[<'CWKEC4G&$(KJ=#I1E.;[&MI.CVVC^,IH[!7-O=:,]PD;G
M<5W`?+GO6<JCG0YI='8UA14*UH]KF`VBZ#I>MV&G:E-,#':"2[V,27F(R(Q@
M<5I[6;HW7R]#'V%-5.1FE!X9T\Z_X7DA@N;*'5$=I8#,P>)E'9N"*7MIN$T^
MA?L(J<'W_0WOA/&L5SXB1<X6Y"C)R<`MU-8X]WY7Y'1@H\LI(CU3Q3XF\_Q*
M;*ZMHK?291C?%EBOI_\`7J*="FU"_4*M>IS22Z#)+S4M3\=Z9>::8(KVYT97
M#3`E$SDDX[U3BHX=Q?1DJ<G74UV+NE^(O$>L>%;&6&:""X-X\%U=LJ[8T7^+
M!..XJ:E"G";7E>Q<*\G3BN[L5CXWUB+P+<:AYL4MY;:A]E,H0;9%SUQVR*)8
M>"J1CT:N"Q$_9M]G8T=:USQ/HFEZ=+<2V;W=Y?!`D:'8L9'"Y/.<]ZFE1IU)
MM=$.I6JTX*7<R+GQ3XNMX?$$1N;+S=)8/)*(SC:>BJO]36BH4K0?\QG[:JI2
M78V]6UGQ!/8Z;=6=S;V%I)8FXGN'"G,N,A`&/?GI7/&G&[3[V-IU9M)K32Y6
MG\8:M/X8\.-:&&+4M7?RVE=,JF.IQ6OU>$9S3VB)XF4HQY=V$OBSQ!HF@ZV=
M4MUDO+"5(H+CR2D<V[OCOCVHC0A4G%0>C$\1.E!\ZU0:?XDUNSUF;2]1O[6^
M:2P>[AE@0#8P!^4XZ]*4J,'%..FMAQJU%*S?2Y#'XQUEO#/AJ^,D1FO[WR9R
M(Q@KN(X';@4_JT74E'L$L3)4XR[DWAL7_P#PLSQ&TES$ZQJ@D`C(+#'R`<\8
M[^M%5)8>&@J;?UB<NQ1M?&6KOX5L#;FWCO[_`%%K5)/+PL:YZ[1U-7/#Q4V[
MZ)7)A6FZ:2ZNQLVVJ^*H+#7K*:V2XU"R"FUG\KRXYMW?GCCZUC*%)SCR[,M5
M*D*<D]T85WK>JW&F>)M&U"_AOO)TX3+-$@7:3]Y?EX.*WA2@G&26[L8NI)J4
M).]D3Q:WJL-GX9T73KR"P-S8>8)YH]P=P.$&>!_]>IE2A>4Y=_\`(I59I*FM
M--_O._T>34)=(MGU2!8+XK^]1&W`'/8^_7\:XJG+S/DV.^ES<BYMSSGXS?\`
M,$_[;_\`M.O5RO[?R_4\O-/L?/\`0\JKV#QS<\&2)#XTTAY'"*)P"3VX(KDQ
M>M)I'5A&HU4V=19V-RE[XWT=D`O[N(M!"6&9`68C'X&O/<DU2ET1VQ7*ZB?4
MUOM26WCH*LZ">TT'RW(8';(!G&:A1<L.X]Y&W.HUT[_9(].6"[\6VNMP/&)-
M3TMG3IE;@``CZT[R5'E?1_@1[KK<U]U<=#/,-6\"'4;@/=QI,+AGD#$-C^(^
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M:QE&U+R,Y1ESU"'41;C4/#YU&!I+7^P]L*-&7`FV\8&/O4H27+*W\WX"E%IQ
MYET%*R6?@_P1J$\4@M[*X+3D(28P3U(JVXRJ5$GN@M*$8.71E_Q#J]]XN\(Z
M\UM9DV%K-&;:148-,H.6.#Z5C1C"A4C=FE:4ZU*5EH&@MHUYJTZ^'=%C$$>G
M,9+H1NK"1EQL&>*N?,HKGEUT]!4^7F]R/3\3GK.]67PUX6TY8+@2V6I#SF,9
M"J2YP,ULK1G-M[HPE=PA&VS.UT:YCM?BGXA@F8I)=11M`"#\X5><'I7+4LZ$
M$NAU4FXU9R>QQUI');>$=%U&2&7[/9ZS)).0A)5<CYL?A75*47*4;[Q_S.:,
M&H1<EL_\CH->\1WWB7PKXF^Q6Y_LZ#RTMYD5@THS\_7MQ7-1IPI5(:G14J2J
MTY::=#%2.T+>))-+MBED=%0)MB**6P-V,CDYK>,E[E_YCG<7K9=#1U2]TT>$
M]&TO6+.2*%M/$MM>HI+1S`<+@#/8?6LXZ5'5@^NQM+2FJ4T]MSNO!T]]<^$=
M,EU)66[,6'WC#$`D`GW(P?QKDQ"BJK4=CKP[DZ2YMSB?C-&YBT:4*=BM*I;L
M"=A`_0_E7?ELU'F3\OU.#,XM\MO/]#RCI7MGB@#@U+2:U!-K84LS-N+,6]<G
M/YU*A%*R17-*][B?KWYJN56L+F;=Q0<<C@^N:GV<1\S0@Z]30HQZ(')]3UGX
M-1L+35Y-IV-*@!['`->+F%DTDSV<N3LVT=CH_AK^R];UC47N!,-0E$@CV8V8
MS^?6N*55N*CV.Y4(J;F;^!G..?6L3<38N,;1C.>E,++8"H(P0,4!:PI`/49Q
M2`3`YX'/6F))+8-B\<#CI[4#`J",$`CIB@5D*`%````'84#22T0U$2,$(H49
MS@#%#;8DDM@\M<Y"J#G/2@+*]Q=HWAL#(&,XYH&&U=NW:,>F*``*JKM"@+Z`
M4!:P;1@#`QZ8H%9`R*WWE!^HH"RO<6D,J:CIEEJUFUIJ%LEQ`W5'''U]C5QG
M*#O$B=.,])(P/^%;^$_^@3_Y,2__`!5=/U[$+[7X(YOJ.'_E_%_YA_PK?PE_
MT"?_`"8E_P#BJ?U[$?S?@O\`(/J.'_E_%_YA_P`*W\)?]`G_`,F)?_BJ/KV(
M_F_!?Y!]1P_\OXO_`##_`(5OX2_Z!/\`Y,2__%4EC:Z^U^"#ZCA_Y?Q?^8?\
M*W\)?]`G_P`F)?\`XJG]>Q'\WX+_`"#ZCA_Y?Q?^8?\`"M_"0_YA/_DQ+_\`
M%4OKV(_F_!?Y!]1P_P#+^+_S.AL-/M-+M$M+&W2"!.B(,"N:4Y3=Y;G5&$8*
MT2S4%!0`4`%`!0`4`%`!0`4`%`!0`4`%`!0`4`%`!0`4`%`!0`4`%`!0`4`%
A`!0`4`%`!0`4`%`!0`4`%`!0`4`%`!0`4`%`!0`4`?_9
`
end
</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
