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Stockholders' Equity - Additional Information (Detail) - USD ($) | 1 Months Ended | 6 Months Ended
--- | --- | ---
May 31, 2017 | Mar. 31, 2017 | Jun. 30, 2017
Class of Stock [Line Items] |  |  |
Proceeds from exercise of warrants |  |  | $ 3,119,000
OrbiMed Israel Partners Limited Partnership [Member] | Ordinary Shares [Member] |  |  |
Class of Stock [Line Items] |  |  |
Number of warrants exercised to purchase shares | 10,737 |  |
Peregrine Management II Ltd. [Member] | Ordinary Shares [Member] |  |  |
Class of Stock [Line Items] |  |  |
Number of warrants exercised to purchase shares | 2,148 |  |
Pontifax [Member] | Ordinary Shares [Member] |  |  |
Class of Stock [Line Items] |  |  |
Number of warrants exercised to purchase shares | 18,940 |  |
Preferred Class B [Member] | OrbiMed Israel Partners Limited Partnership [Member] |  |  |
Class of Stock [Line Items] |  |  |
Number of warrants exercised to purchase shares | 149,686 | 22,679 |
Warrant exercise price |  | $ 17.64 |
Proceeds from exercise of warrants | $ 2,600,000 | $ 400,000 |
Preferred Class B [Member] | OrbiMed Israel Partners Limited Partnership [Member] | Weighted Average [Member] |  |  |
Class of Stock [Line Items] |  |  |
Warrant exercise price | $ 16.46 |  |
Preferred Class B [Member] | Peregrine Management II Ltd. [Member] |  |  |
Class of Stock [Line Items] |  |  |
Number of warrants exercised to purchase shares | 4,460 |  |
Proceeds from exercise of warrants | $ 79,000 |  |
Preferred Class B [Member] | Peregrine Management II Ltd. [Member] | Weighted Average [Member] |  |  |
Class of Stock [Line Items] |  |  |
Warrant exercise price | $ 11.91 |  |

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- Definition Exercise price per share or per unit of warrants or rights outstanding. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 235 -SubTopic 10 -Section S99 -Paragraph 1 -Subparagraph (SX 210.4-08.(i)(4)) -URI http://asc.fasb.org/extlink&oid=26873400&loc=d3e23780-122690 + Details
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- Definition Number of securities into which the class of warrant or right may be converted. For example, but not limited to, 500,000 warrants may be converted into 1,000,000 shares. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 235 -SubTopic 10 -Section S99 -Paragraph 1 -Subparagraph (SX 210.4-08.(i)(2)) -URI http://asc.fasb.org/extlink&oid=26873400&loc=d3e23780-122690 + Details
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