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Reverse Merger - Summary of Combined Results of Operations of Company and Tokai, on a Pro Forma Basis (Detail) - USD ($)
$ / shares in Units, $ in Thousands
 3 Months Ended 6 Months Ended
Jun. 30, 2017
Jun. 30, 2016
Jun. 30, 2017
Jun. 30, 2016
Operating expenses        
Research and development $ 686 $ 10,487 $ 1,471 $ 19,109
General and administrative 2,592 4,020 5,474 7,991
Total operating expenses 3,278 14,507 6,945 27,100
Loss from operations (3,278) (14,507) (6,945) (27,100)
Other income, net 18 (21) 55 42
Net loss and comprehensive loss $ (3,260) $ (14,528) $ (6,890) $ (27,058)
Net loss per share, basic and diluted $ (0.47) $ (2.20) $ (0.99) $ (4.10)
Weighted-average shares outstanding, basic and diluted 6,943,831 6,605,009 6,943,831 6,605,009