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Business Acquisition - Schedule of Unaudited Pro Forma Combined Financial Information (Detail) - USD ($) $ / shares in Units, $ in Thousands | 3 Months Ended | 9 Months Ended
--- | --- | ---
Sep. 30, 2020 | Sep. 30, 2019 | Sep. 30, 2020 | Sep. 30, 2019
Business Combinations [Abstract] |  |  |  |
Revenue | $ 120 | $ 250 | $ 120 | $ 250
Operating expenses |  |  |  |
Research and development | 1,779 | 2,267 | 6,556 | 9,077
General and administrative | 1,918 | 1,761 | 5,622 | 6,141
Restructuring expense | 1,802 |  | 2,292 |
Total operating expenses | 5,499 | 4,028 | 14,470 | 15,218
Loss from operations | (5,379) | (3,778) | (14,350) | (14,968)
Other income (expense), net | 4 | 27 | (4,790) | 17
Net loss and other comprehensive loss | $ (5,375) | $ (3,751) | $ (19,140) | $ (14,951)
Net loss per share, basic and diluted | $ (4.28) | $ (4.18) | $ (16.35) | $ (18.49)
Weighted-average shares outstanding, basic and diluted | 1,257,194 | 896,318 | 1,170,608 | 808,675

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