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Business Acquisition - Schedule of Unaudited Pro Forma Combined Financial Information (Detail) - USD ($)
$ / shares in Units, $ in Thousands
 3 Months Ended 9 Months Ended
Sep. 30, 2020
Sep. 30, 2019
Sep. 30, 2020
Sep. 30, 2019
Business Combinations [Abstract]        
Revenue $ 120 $ 250 $ 120 $ 250
Operating expenses        
Research and development 1,779 2,267 6,556 9,077
General and administrative 1,918 1,761 5,622 6,141
Restructuring expense 1,802   2,292  
Total operating expenses 5,499 4,028 14,470 15,218
Loss from operations (5,379) (3,778) (14,350) (14,968)
Other income (expense), net 4 27 (4,790) 17
Net loss and other comprehensive loss $ (5,375) $ (3,751) $ (19,140) $ (14,951)
Net loss per share, basic and diluted $ (4.28) $ (4.18) $ (16.35) $ (18.49)
Weighted-average shares outstanding, basic and diluted 1,257,194 896,318 1,170,608 808,675