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Business Acquisition - Schedule of Unaudited Pro Forma Combined Financial Information (Detail) - USD ($) $ / shares in Units, $ in Thousands | 12 Months Ended
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Dec. 31, 2020 | Dec. 31, 2019
Business Combinations [Abstract] |  |
Revenue | $ 120 | $ 500
Operating expenses |  |
Research and development | 9,489 | 11,441
General and administrative | 8,317 | 7,585
Restructuring expense | 2,282 |
Goodwill impairment |  | 1,867
Total operating expenses | 20,088 | 20,893
Loss from operations | (19,968) | (20,393)
Other income (expense), net | 79 | 40
Warrant inducement expense | (4,829) |
Loss before provision for income taxes | (24,718) | (20,353)
Income tax benefit | 404 |
Net loss and other comprehensive loss | $ (24,314) | $ (20,353)
Net loss per share, basic and diluted | $ (15.44) | $ (24.49)
Weighted-average shares outstanding, basic and diluted | 1,574,657 | 831,014

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