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Business Acquisition - Schedule of Unaudited Pro Forma Combined Financial Information (Detail) - USD ($)
$ / shares in Units, $ in Thousands
 12 Months Ended
Dec. 31, 2020
Dec. 31, 2019
Business Combinations [Abstract]    
Revenue $ 120 $ 500
Operating expenses    
Research and development 9,489 11,441
General and administrative 8,317 7,585
Restructuring expense 2,282  
Goodwill impairment   1,867
Total operating expenses 20,088 20,893
Loss from operations (19,968) (20,393)
Other income (expense), net 79 40
Warrant inducement expense (4,829)  
Loss before provision for income taxes (24,718) (20,353)
Income tax benefit 404  
Net loss and other comprehensive loss $ (24,314) $ (20,353)
Net loss per share, basic and diluted $ (15.44) $ (24.49)
Weighted-average shares outstanding, basic and diluted 1,574,657 831,014