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Business Acquisition - Summary of Fair Value of Purchase Price Consideration (Parenthetical) (Detail) - $ / shares |  | 12 Months Ended
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Sep. 14, 2020 | Dec. 31, 2021 | Dec. 31, 2020
Business Acquisition [Line Items] |  |  |
Expected stock price volatility, minimum |  | 105.00% | 74.00%
Expected stock price volatility, maximum |  | 110.00% | 87.00%
Expected life of option (in years) |  |  | 6 years
Risk-free interest rate, minimum |  |  | 1.00%
Risk-free interest rate, maximum |  | 1.00% | 3.00%
Minimum [Member] |  |  |
Business Acquisition [Line Items] |  |  |
Expected life of option (in years) |  | 6 years 3 months |
Maximum [Member] |  |  |
Business Acquisition [Line Items] |  |  |
Expected life of option (in years) |  | 6 years 9 months |
Anelixis [Member] |  |  |
Business Acquisition [Line Items] |  |  |
Expected stock price volatility, minimum | 82.00% |  |
Expected stock price volatility, maximum | 83.00% |  |
Risk-free interest rate, minimum | 0.27% |  |
Risk-free interest rate, maximum | 0.45% |  |
Anelixis [Member] | Minimum [Member] |  |  |
Business Acquisition [Line Items] |  |  |
Expected life of option (in years) | 5 years |  |
Anelixis [Member] | Maximum [Member] |  |  |
Business Acquisition [Line Items] |  |  |
Expected life of option (in years) | 5 years 10 months 24 days |  |
Common Stock [Member] | Anelixis [Member] |  |  |
Business Acquisition [Line Items] |  |  |
Business acquisition, shares issued | 175,488 |  |
Business acquisition, closing price per share | $ 6.80 |  |

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- Definition Number of shares of equity interests issued or issuable to acquire entity. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 805 -SubTopic 30 -Section 50 -Paragraph 1 -Subparagraph (b)(4) -URI http://asc.fasb.org/extlink&oid=120321790&loc=d3e6927-128479 + Details
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- Definition Line items represent financial concepts included in a table. These concepts are used to disclose reportable information associated with domain members defined in one or many axes to the table. + References No definition available. + Details
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- Definition The estimated measure of the maximum percentage by which a share price is expected to fluctuate during a period. Volatility also may be defined as a probability-weighted measure of the dispersion of returns about the mean. The volatility of a share price is the standard deviation of the continuously compounded rates of return on the share over a specified period. That is the same as the standard deviation of the differences in the natural logarithms of the stock prices plus dividends, if any, over the period. + References No definition available. + Details
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- Definition The estimated measure of the minimum percentage by which a share price is expected to fluctuate during a period. Volatility also may be defined as a probability-weighted measure of the dispersion of returns about the mean. The volatility of a share price is the standard deviation of the continuously compounded rates of return on the share over a specified period. That is the same as the standard deviation of the differences in the natural logarithms of the stock prices plus dividends, if any, over the period. + References No definition available. + Details
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- Definition The maximum risk-free interest rate assumption that is used in valuing an option on its own shares. + References No definition available. + Details
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