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Summary of Significant Accounting Policies - Additional Information (Detail) |  |  |  | 12 Months Ended |  |
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Dec. 23, 2020 USD ($) shares | Dec. 18, 2020 shares | Sep. 14, 2020 USD ($) shares | Dec. 31, 2021 USD ($) Segment Reporting_Unit shares | Dec. 31, 2020 USD ($) shares | Mar. 31, 2020 shares | Dec. 31, 2019 USD ($)
Summary Of Significant Accounting Policies [Line Items] |  |  |  |  |  |  |
Net loss |  |  |  | $ (34,506,000) | $ (22,811,000) |  |
Cash used in operating activities |  |  |  | (28,913,000) | (15,212,000) |  |
Cash and cash equivalents |  |  |  | 84,833,000 | 114,195,000 |  | $ 8,791,000
Working capital |  |  |  | 83,900,000 |  |  |
Accumulated deficit |  |  |  | $ (114,899,000) | (80,393,000) |  |
Proceeds from issuance of common stock, net |  |  |  |  | 9,000,000 |  |
Reverse stock split, description |  |  |  | one-for-eighteen |  |  |
Cash, cash equivalents and restricted cash, maturity period |  |  |  | three months or less |  |  |
Cash equivalents |  |  |  | $ 9,200,000 | 9,200,000 |  |
Financial assets transfers level 1 to 2 |  |  |  | 0 | 0 |  |
Financial assets transfers level 2 to 1 |  |  |  | 0 | 0 |  |
Financial liabilities transfers level 1 to 2 |  |  |  | 0 | 0 |  |
Financial liabilities transfers level 2 to 1 |  |  |  | $ 0 | 0 |  |
Number of operating business segments | Segment |  |  |  | 1 |  |  |
Number of reporting units | Reporting_Unit |  |  |  | 1 |  |  |
Impairment charge |  |  |  | $ 0 |  |  |
Impairments of long-lived assets |  |  |  | $ 0 | $ 0 |  |
Antidilutive securities excluded from computation of earnings per share, amount | shares |  |  |  | 1,087,174 | 632,543 |  |
Expected life assumption using simplified method |  |  |  |  | 6 years |  |
Tax benefit |  |  |  | $ 0 |  |  |
Income tax examination, likelihood of settlement, description |  |  |  | The second step is to measure the tax benefit as the largest amount that is more than 50% likely of being realized upon settlement. |  |  |
Income tax examination, likelihood of settlement, percentage |  |  |  | 50.00% |  |  |
2014 Stock Incentive Plan [Member] |  |  |  |  |  |  |
Summary Of Significant Accounting Policies [Line Items] |  |  |  |  |  |  |
Increase in number of shares of common stock authorized for issuance | shares |  |  |  |  |  | 28,816 |
Common stock, number of shares reserved for issuance | shares |  |  |  | 0 |  |  |
Equity compensation period |  |  |  | 10 years |  |  |
2014 Employee Stock Purchase Plan [Member] |  |  |  |  |  |  |
Summary Of Significant Accounting Policies [Line Items] |  |  |  |  |  |  |
Increase in number of shares of common stock authorized for issuance | shares |  |  |  |  |  | 7,204 |
Common stock, number of shares reserved for issuance | shares |  |  |  | 24,077 |  |  |
2020 Plan [Member] |  |  |  |  |  |  |
Summary Of Significant Accounting Policies [Line Items] |  |  |  |  |  |  |
Common stock, number of shares reserved for issuance | shares |  | 4,860,000 |  | 4,077,417 |  |  |
Percentage of issued and outstanding shares of common stock |  | 15.00% |  |  |  |  |
Equity compensation period |  | 3 years |  |  |  |  |
Stock Options [Member] | Board of Directors [Member] |  |  |  |  |  |  |
Summary Of Significant Accounting Policies [Line Items] |  |  |  |  |  |  |
Expected life assumption using simplified method, description |  |  |  | For stock options granted to the Company’s board of directors (the “Board”), the Company determined the expected life assumption using the simplified method as the starting point with an average period of twelve (12) months added to take into account for the extended range of time of 12 to 18 months vested stock options granted to Board members may be exercised upon termination. |  |  |
Expected life assumption using simplified method |  |  |  | 12 months |  |  |
Fair Value, Measurements, Recurring [Member] |  |  |  |  |  |  |
Summary Of Significant Accounting Policies [Line Items] |  |  |  |  |  |  |
Assets measured at fair value |  |  |  | $ 0 | $ 0 |  |
Liabilities measured at fair value |  |  |  | $ 0 | $ 0 |  |
Maximum [Member] |  |  |  |  |  |  |
Summary Of Significant Accounting Policies [Line Items] |  |  |  |  |  |  |
Expected life assumption using simplified method |  |  |  | 6 years 9 months |  |  |
Maximum [Member] | Stock Options [Member] | Board of Directors [Member] |  |  |  |  |  |  |
Summary Of Significant Accounting Policies [Line Items] |  |  |  |  |  |  |
Vesting period of stock options granted |  |  |  | 12 months |  |  |
Minimum [Member] |  |  |  |  |  |  |
Summary Of Significant Accounting Policies [Line Items] |  |  |  |  |  |  |
Expected life assumption using simplified method |  |  |  | 6 years 3 months |  |  |
Minimum [Member] | Stock Options [Member] | Board of Directors [Member] |  |  |  |  |  |  |
Summary Of Significant Accounting Policies [Line Items] |  |  |  |  |  |  |
Vesting period of stock options granted |  |  |  | 18 months |  |  |
Series X1 Preferred Stock [Member] | Stock Purchase Agreement [Member] |  |  |  |  |  |  |
Summary Of Significant Accounting Policies [Line Items] |  |  |  |  |  |  |
Proceeds from issuance of common stock, net | $ 9,000,000.0 |  |  |  |  |  |
Common Stock [Member] |  |  |  |  |  |  |
Summary Of Significant Accounting Policies [Line Items] |  |  |  |  |  |  |
Proceeds from issuance of common stock, net | $ 9,000,000.0 |  |  |  |  |  |
Common stock, number of shares sold | shares | 1,004,111 |  |  |  | 1,004,111 |  |
Common Stock [Member] | Series X1 Preferred Stock [Member] | Stock Purchase Agreement [Member] |  |  |  |  |  |  |
Summary Of Significant Accounting Policies [Line Items] |  |  |  |  |  |  |
Common stock, number of shares sold | shares | 1,004,111 |  |  |  |  |  |
Anelixis [Member] | Maximum [Member] |  |  |  |  |  |  |
Summary Of Significant Accounting Policies [Line Items] |  |  |  |  |  |  |
Expected life assumption using simplified method |  |  | 5 years 10 months 24 days |  |  |  |
Anelixis [Member] | Minimum [Member] |  |  |  |  |  |  |
Summary Of Significant Accounting Policies [Line Items] |  |  |  |  |  |  |
Expected life assumption using simplified method |  |  | 5 years |  |  |  |
Anelixis [Member] | Series X1 Preferred Stock [Member] | Stock Purchase Agreement [Member] |  |  |  |  |  |  |
Summary Of Significant Accounting Policies [Line Items] |  |  |  |  |  |  |
Convertible preferred stock shares agreed to sell | shares |  |  | 199,112 |  |  |  |
Convertible preferred stock shares aggregate purchase price |  |  | $ 99,100,000 |  |  |  |
Business combination additional commitments in equity financing |  |  | $ 9,000,000.0 |  |  |  |
Anelixis [Member] | Common Stock [Member] |  |  |  |  |  |  |
Summary Of Significant Accounting Policies [Line Items] |  |  |  |  |  |  |
Shares of common stock issued upon conversion of each share of preferred stock | shares |  |  | 55.5556 |  |  |  |
Anelixis [Member] | Common Stock [Member] | Series X1 Preferred Stock [Member] | Stock Purchase Agreement [Member] |  |  |  |  |  |  |
Summary Of Significant Accounting Policies [Line Items] |  |  |  |  |  |  |
Shares of common stock issued upon conversion of each share of preferred stock | shares |  |  | 55.5556 |  |  |  |
Otic Pharma [Member] | Anelixis [Member] |  |  |  |  |  |  |
Summary Of Significant Accounting Policies [Line Items] |  |  |  |  |  |  |
Ownership percentage |  |  |  | 100.00% |  |  |
Otic Pharma, Inc. [Member] |  |  |  |  |  |  |
Summary Of Significant Accounting Policies [Line Items] |  |  |  |  |  |  |
Ownership percentage |  |  |  | 100.00% |  |  |

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