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Summary of Significant Accounting Policies - Additional Information (Detail)
 12 Months Ended
Dec. 23, 2020
USD ($)
shares
Dec. 18, 2020
shares
Sep. 14, 2020
USD ($)
shares
Dec. 31, 2021
USD ($)
Segment
Reporting_Unit
shares
Dec. 31, 2020
USD ($)
shares
Mar. 31, 2020
shares
Dec. 31, 2019
USD ($)
Summary Of Significant Accounting Policies [Line Items]              
Net loss       $ (34,506,000) $ (22,811,000)    
Cash used in operating activities       (28,913,000) (15,212,000)    
Cash and cash equivalents       84,833,000 114,195,000   $ 8,791,000
Working capital       83,900,000      
Accumulated deficit       $ (114,899,000) (80,393,000)    
Proceeds from issuance of common stock, net         9,000,000    
Reverse stock split, description       one-for-eighteen      
Cash, cash equivalents and restricted cash, maturity period       three months or less      
Cash equivalents       $ 9,200,000 9,200,000    
Financial assets transfers level 1 to 2       0 0    
Financial assets transfers level 2 to 1       0 0    
Financial liabilities transfers level 1 to 2       0 0    
Financial liabilities transfers level 2 to 1       $ 0 0    
Number of operating business segments | Segment       1      
Number of reporting units | Reporting_Unit       1      
Impairment charge       $ 0      
Impairments of long-lived assets       $ 0 $ 0    
Antidilutive securities excluded from computation of earnings per share, amount | shares       1,087,174 632,543    
Expected life assumption using simplified method         6 years    
Tax benefit       $ 0      
Income tax examination, likelihood of settlement, description       The second step is to measure the tax benefit as the largest amount that is more than 50% likely of being realized upon settlement.      
Income tax examination, likelihood of settlement, percentage       50.00%      
2014 Stock Incentive Plan [Member]              
Summary Of Significant Accounting Policies [Line Items]              
Increase in number of shares of common stock authorized for issuance | shares           28,816  
Common stock, number of shares reserved for issuance | shares       0      
Equity compensation period       10 years      
2014 Employee Stock Purchase Plan [Member]              
Summary Of Significant Accounting Policies [Line Items]              
Increase in number of shares of common stock authorized for issuance | shares           7,204  
Common stock, number of shares reserved for issuance | shares       24,077      
2020 Plan [Member]              
Summary Of Significant Accounting Policies [Line Items]              
Common stock, number of shares reserved for issuance | shares   4,860,000   4,077,417      
Percentage of issued and outstanding shares of common stock   15.00%          
Equity compensation period   3 years          
Stock Options [Member] | Board of Directors [Member]              
Summary Of Significant Accounting Policies [Line Items]              
Expected life assumption using simplified method, description       For stock options granted to the Company’s board of directors (the “Board”), the Company determined the expected life assumption using the simplified method as the starting point with an average period of twelve (12) months added to take into account for the extended range of time of 12 to 18 months vested stock options granted to Board members may be exercised upon termination.      
Expected life assumption using simplified method       12 months      
Fair Value, Measurements, Recurring [Member]              
Summary Of Significant Accounting Policies [Line Items]              
Assets measured at fair value       $ 0 $ 0    
Liabilities measured at fair value       $ 0 $ 0    
Maximum [Member]              
Summary Of Significant Accounting Policies [Line Items]              
Expected life assumption using simplified method       6 years 9 months      
Maximum [Member] | Stock Options [Member] | Board of Directors [Member]              
Summary Of Significant Accounting Policies [Line Items]              
Vesting period of stock options granted       12 months      
Minimum [Member]              
Summary Of Significant Accounting Policies [Line Items]              
Expected life assumption using simplified method       6 years 3 months      
Minimum [Member] | Stock Options [Member] | Board of Directors [Member]              
Summary Of Significant Accounting Policies [Line Items]              
Vesting period of stock options granted       18 months      
Series X1 Preferred Stock [Member] | Stock Purchase Agreement [Member]              
Summary Of Significant Accounting Policies [Line Items]              
Proceeds from issuance of common stock, net $ 9,000,000.0            
Common Stock [Member]              
Summary Of Significant Accounting Policies [Line Items]              
Proceeds from issuance of common stock, net $ 9,000,000.0            
Common stock, number of shares sold | shares 1,004,111       1,004,111    
Common Stock [Member] | Series X1 Preferred Stock [Member] | Stock Purchase Agreement [Member]              
Summary Of Significant Accounting Policies [Line Items]              
Common stock, number of shares sold | shares 1,004,111            
Anelixis [Member] | Maximum [Member]              
Summary Of Significant Accounting Policies [Line Items]              
Expected life assumption using simplified method     5 years 10 months 24 days        
Anelixis [Member] | Minimum [Member]              
Summary Of Significant Accounting Policies [Line Items]              
Expected life assumption using simplified method     5 years        
Anelixis [Member] | Series X1 Preferred Stock [Member] | Stock Purchase Agreement [Member]              
Summary Of Significant Accounting Policies [Line Items]              
Convertible preferred stock shares agreed to sell | shares     199,112        
Convertible preferred stock shares aggregate purchase price     $ 99,100,000        
Business combination additional commitments in equity financing     $ 9,000,000.0        
Anelixis [Member] | Common Stock [Member]              
Summary Of Significant Accounting Policies [Line Items]              
Shares of common stock issued upon conversion of each share of preferred stock | shares     55.5556        
Anelixis [Member] | Common Stock [Member] | Series X1 Preferred Stock [Member] | Stock Purchase Agreement [Member]              
Summary Of Significant Accounting Policies [Line Items]              
Shares of common stock issued upon conversion of each share of preferred stock | shares     55.5556        
Otic Pharma [Member] | Anelixis [Member]              
Summary Of Significant Accounting Policies [Line Items]              
Ownership percentage       100.00%      
Otic Pharma, Inc. [Member]              
Summary Of Significant Accounting Policies [Line Items]              
Ownership percentage       100.00%