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Consolidated Statements of Operations and Comprehensive Loss - USD ($)
$ in Thousands
 12 Months Ended
Dec. 31, 2021
Dec. 31, 2020
Operating expenses    
Research and development $ 23,735 $ 6,131
General and administrative 13,132 10,052
Restructuring expense 2,300 2,282
Total operating expenses 36,867 18,465
Loss from operations (36,867) (18,465)
Other income, net 7 79
Warrant inducement expense   (4,829)
Loss before income tax benefit (36,860) (23,215)
Income tax benefit 2,354 404
Net loss and comprehensive loss $ (34,506) $ (22,811)
Net loss per share, basic and diluted $ (2.33) $ (15.72)
Weighted-average common shares outstanding, basic and diluted 14,819,582 1,451,432