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Summary of Significant Accounting Policies - Additional Information (Detail) |  | 12 Months Ended |
--- | --- | --- | ---
Dec. 18, 2020 shares | Dec. 31, 2022 USD ($) Reporting_Unit Segment $ / shares shares | Dec. 31, 2021 USD ($) shares | Mar. 31, 2020 shares
Summary Of Significant Accounting Policies [Line Items] |  |  |  |
Cash, cash equivalents and restricted cash, maturity period |  | three months or less |  |
Cash equivalents |  | $ 9,300,000 | $ 9,300,000 |
Financial assets transfers between level amount |  | 0 | 0 |
Financial liabilities transfers between level amount |  | $ 0 | 0 |
Number of operating business segments | Segment |  | 1 |  |
Number of reporting units | Reporting_Unit |  | 1 |  |
Impairment charge |  | $ 48,648,000 | 0 |
Impairments of long-lived assets |  | $ 0 | $ 0 |
Basic weighted average shares outstanding | shares |  | 14,285,254 | 14,819,582 |
Warrants exercise price | $ / shares |  | $ 0.001 |  |
Antidilutive securities excluded from computation of earnings per share, amount | shares |  | 8,139,155 | 1,087,174 |
Tax benefit |  | $ 0 |  |
Income tax examination, likelihood of settlement, description |  | The second step is to measure the tax benefit as the largest amount that is more than 50% likely of being realized upon settlement. |  |
Income tax examination, likelihood of settlement, percentage |  | 50.00% |  |
2014 Stock Incentive Plan [Member] |  |  |  |
Summary Of Significant Accounting Policies [Line Items] |  |  |  |
Increase in number of shares of common stock authorized for issuance | shares |  |  |  | 28,816
Common stock, number of shares initially reserved for issuance | shares |  | 0 |  |
Equity compensation period |  | 10 years |  |
2014 Employee Stock Purchase Plan [Member] |  |  |  |
Summary Of Significant Accounting Policies [Line Items] |  |  |  |
Increase in number of shares of common stock authorized for issuance | shares |  |  |  | 7,204
Common stock, number of shares initially reserved for issuance | shares |  | 24,077 |  |
2020 Plan [Member] |  |  |  |
Summary Of Significant Accounting Policies [Line Items] |  |  |  |
Common stock, number of shares initially reserved for issuance | shares | 4,860,000 | 3,126,608 |  |
Percentage of issued and outstanding shares of common stock | 15.00% |  |  |
Equity compensation period | 3 years |  |  |
Stock Options [Member] | Board of Directors [Member] |  |  |  |
Summary Of Significant Accounting Policies [Line Items] |  |  |  |
Expected life assumption using simplified method, description |  | For stock options granted to the Company’s board of directors (the “Board”), the Company determined the expected life assumption using the simplified method as the starting point with an average period of twelve (12) months added to take into account for the extended range of time of 12 to 18 months vested stock options granted to Board members may be exercised upon termination. |  |
Expected life assumption using simplified method |  | 12 months |  |
Fair Value, Measurements, Recurring [Member] |  |  |  |
Summary Of Significant Accounting Policies [Line Items] |  |  |  |
Assets measured at fair value |  | $ 0 | $ 0 |
Liabilities measured at fair value |  | $ 0 | $ 0 |
Maximum [Member] |  |  |  |
Summary Of Significant Accounting Policies [Line Items] |  |  |  |
Expected life assumption using simplified method |  | 6 years 6 months | 6 years 9 months |
Maximum [Member] | Stock Options [Member] | Board of Directors [Member] |  |  |  |
Summary Of Significant Accounting Policies [Line Items] |  |  |  |
Vesting period of stock options granted |  | 18 months |  |
Minimum [Member] |  |  |  |
Summary Of Significant Accounting Policies [Line Items] |  |  |  |
Expected life assumption using simplified method |  | 6 years 3 months | 6 years 3 months |
Minimum [Member] | Stock Options [Member] | Board of Directors [Member] |  |  |  |
Summary Of Significant Accounting Policies [Line Items] |  |  |  |
Vesting period of stock options granted |  | 12 months |  |
Warrants [Member] |  |  |  |
Summary Of Significant Accounting Policies [Line Items] |  |  |  |
Basic weighted average shares outstanding | shares |  | 509,117 |  |
Anelixis [Member] |  |  |  |
Summary Of Significant Accounting Policies [Line Items] |  |  |  |
Impairment charge |  | $ 48,600,000 |  |
Anelixis Therapeutics, LLC and Otic Pharma, Ltd. |  |  |  |
Summary Of Significant Accounting Policies [Line Items] |  |  |  |
Ownership interest percentage |  | 100.00% |  |
Otic Pharma, Inc. [Member] |  |  |  |
Summary Of Significant Accounting Policies [Line Items] |  |  |  |
Ownership interest percentage |  | 100.00% |  |

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