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Stockholders' Equity - Additional Information (Detail) - USD ($)
 9 Months Ended
May 16, 2023
May 05, 2023
Jan. 11, 2022
Sep. 30, 2023
Jul. 14, 2023
Jul. 10, 2023
Apr. 28, 2023
Dec. 31, 2022
Mar. 31, 2021
Class Of Stock [Line Items]                  
Warrants available for exercise       22,217,302          
Debt outstanding       $ 0          
Common stock, shares issued       23,545,130       13,776,788  
Common stock, par value, per share       $ 0.001       $ 0.001  
Net proceeds after deducting offering costs       $ 33,017,000          
Securities Purchase Agreement [Member]                  
Class Of Stock [Line Items]                  
Number of days after registration settlement       90 days          
Armistice Capital Master Fund Ltd [Member] | Securities Purchase Agreement [Member]                  
Class Of Stock [Line Items]                  
Number of pre-funded warrants exercised for common stock           501,197      
Common stock, shares issued         501,197        
Warrants exercise price           $ 0.001      
Series X1 Preferred Stock [Member]                  
Class Of Stock [Line Items]                  
Warrants available for exercise       50,207.419          
Shares of common stock issued upon conversion of each share of preferred stock       2,789,301          
Common Stock [Member]                  
Class Of Stock [Line Items]                  
Warrants available for exercise       22,217,302          
Private Placement Warrants [Member]                  
Class Of Stock [Line Items]                  
Warrants available for exercise       15,489,340          
Private Placement Warrants [Member] | Accredited Investor [Member]                  
Class Of Stock [Line Items]                  
Warrants exercise price             $ 3    
Private Placement Warrants [Member] | Securities Purchase Agreement Initial Closing [Member]                  
Class Of Stock [Line Items]                  
Common warrants issued   $ 35,000,000              
Net proceeds after deducting offering costs   $ 33,000,000              
Private Placement Warrants [Member] | Securities Purchase Agreement Initial Closing [Member] | Accredited Investor [Member]                  
Class Of Stock [Line Items]                  
Common stock, shares issued   8,730,168         15,151,518    
Common stock, par value, per share             $ 0.001    
Common stock warrants exercisable   15,151,518         15,151,518    
Common warrants issued   $ 45,500,000              
Private Placement Warrants [Member] | Securities Purchase Agreement Second Closing [Member] | Accredited Investor [Member]                  
Class Of Stock [Line Items]                  
Common stock, shares issued             20,202,024    
Private Placement Warrants [Member] | Securities Purchase Agreement Third Closing [Member] | Accredited Investor [Member]                  
Class Of Stock [Line Items]                  
Common stock, shares issued             25,252,530    
Private Placement Warrants [Member] | Securities Purchase Agreement Second and Third Closing [Member] | Accredited Investor [Member]                  
Class Of Stock [Line Items]                  
Common warrants issued   $ 105,000,000              
Private Placement Warrants [Member] | Common Stock [Member] | Securities Purchase Agreement Initial Closing [Member]                  
Class Of Stock [Line Items]                  
Common stock, shares issued   8,730,168              
Private Placement Warrants [Member] | Pre-funded Warrants [Member] | Accredited Investor [Member]                  
Class Of Stock [Line Items]                  
Warrants exercise price             $ 0.001    
Private Placement Warrants [Member] | Pre-funded Warrants [Member] | Securities Purchase Agreement Initial Closing [Member]                  
Class Of Stock [Line Items]                  
Common stock, shares issued   6,421,350              
Jefferies LLC [Member] | ATM Program [Member]                  
Class Of Stock [Line Items]                  
Common stock number of shares issued       0          
Equity distribution agreement maximum value of common shares issuable                 $ 75,000,000
Public float minimum balance to be maintained       $ 75,000,000          
Jefferies LLC [Member] | Maximum [Member] | ATM Program [Member]                  
Class Of Stock [Line Items]                  
Equity distribution agreement maximum value of common shares issuable       $ 10,600,000          
BVF Exchanging Stockholders [Member] | Series X1 Non-voting Convertible Preferred Stock [Member] | Series X1 Exchange Agreement [Member]                  
Class Of Stock [Line Items]                  
Conversion of stock, shares issued     9,899.99            
BVF Exchanging Stockholders [Member] | Common Stock [Member] | Series X1 Exchange Agreement [Member]                  
Class Of Stock [Line Items]                  
Conversion of stock, shares converted     550,000            
Cormorant Global Healthcare Master Fund LP [Member] | Series X Non-Voting Convertible Preferred Stock [Member] | Conversion Agreement [Member]                  
Class Of Stock [Line Items]                  
Conversion of stock, shares converted 1,782                
Cormorant Global Healthcare Master Fund LP [Member] | Series X1 Non-voting Convertible Preferred Stock [Member] | Conversion Agreement [Member]                  
Class Of Stock [Line Items]                  
Conversion of stock, shares converted 7,883.586                
Cormorant Global Healthcare Master Fund LP [Member] | Common Stock [Member] | Series X Non-Voting Convertible Preferred Stock [Member] | Conversion Agreement [Member]                  
Class Of Stock [Line Items]                  
Conversion of stock, shares issued 99,000                
Cormorant Global Healthcare Master Fund LP [Member] | Common Stock [Member] | Series X1 Non-voting Convertible Preferred Stock [Member] | Conversion Agreement [Member]                  
Class Of Stock [Line Items]                  
Conversion of stock, shares issued 437,977