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Consolidated Statements of Cash Flows - USD ($)
 12 Months Ended
Dec. 31, 2023
Dec. 31, 2022
Cash flows used in operating activities:    
Net loss $ (40,326,000) $ (87,966,000)
Adjustments to reconcile net loss to net cash used in operating activities:    
Amortization of operating lease asset 374,000 373,000
Accretion on investment discounts (1,203,000)  
Goodwill impairment 0 48,648,000
Stock-based compensation 6,545,000 8,153,000
Changes in operating assets and liabilities:    
Prepaid expenses and other assets (1,954,000) 654,000
Accounts payable, accrued expenses and other liabilities (2,600,000) 2,081,000
Operating lease liabilities (363,000) (367,000)
Net cash used in operating activities (39,527,000) (28,424,000)
Cash flows from investing activities:    
Purchase of available-for-sale short-term investments (78,287,000)  
Proceeds from maturities of available-for-sale short-term investments 33,000,000  
Net cash used in investing activities (45,287,000)  
Cash flows from financing activities:    
Proceeds from issuances of common stock and pre-funded warrants, net 33,017,000  
Net cash used in financing activities 33,017,000  
Net change in cash and cash equivalents (51,797,000) (28,424,000)
Cash and cash equivalents at beginning of year 56,409,000 84,833,000
Cash and cash equivalents at end of year 4,612,000 56,409,000
Non-cash activities:    
Common stock exchanged for X and X1 non-voting convertible preferred stock $ 1,000 1,000
Increase in operating lease asset and liability due to lease modification   $ 344,000