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Stockholders' Equity - Additional Information (Detail) - USD ($) $ / shares in Units, $ in Thousands |  |  |  |  |  |  |  |  |  |  |  | 12 Months Ended |  |  |  |  |  |  |  |  |  |  |  |  |
--- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | ---
Oct. 30, 2024 | Oct. 29, 2024 | Oct. 01, 2024 | Sep. 30, 2024 | Sep. 20, 2024 | Jul. 08, 2024 | May 06, 2024 | May 16, 2023 | May 05, 2023 | Apr. 28, 2023 | Jan. 11, 2022 | Dec. 31, 2024 | Dec. 31, 2023 | Jun. 30, 2025 | Jul. 11, 2024 | Jun. 30, 2024 | May 09, 2024 | May 07, 2024 | Mar. 31, 2024 | Jan. 30, 2024 | Nov. 06, 2023 | Nov. 02, 2023 | Jul. 14, 2023 | Jul. 10, 2023 | Dec. 31, 2022 | Sep. 14, 2020
Class Of Stock [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Percentage of common stockholders receive cash and other assets |  |  |  |  |  |  |  |  |  |  |  | 50.00% |  | 50.00% |  |  |  |  |  |  |  |  |  |  |  |
Common stock, shares issued |  |  |  |  |  |  |  |  |  |  |  | 59,789,275 | 24,213,130 |  |  |  |  |  |  |  |  |  |  |  |  |
Common stock, par value |  |  |  |  |  |  |  |  |  |  |  | $ 0.001 | $ 0.001 | $ 0.001 |  |  |  |  |  |  |  |  |  |  |  |
Preferred stock, shares authorized |  |  |  |  |  |  |  |  |  |  |  | 5,000,000 |  |  |  |  |  |  |  |  |  |  |  |  |  |
Preferred stock, par value |  |  |  |  |  |  |  |  |  |  |  | $ 0.001 |  |  |  |  |  |  |  |  |  |  |  |  |  |
Net proceeds after deducting offering costs |  |  |  |  |  |  |  |  |  |  |  | $ 133,307 | $ 33,017 |  |  |  |  |  |  |  |  |  |  |  |  |
Armistice Capital Master Fund Ltd [Member] | Securities Purchase Agreement [Member] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Class Of Stock [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Common stock, shares issued |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 240,000 |  | 583,000 |  |  | 600,000 | 653,000 |  | 501,197 |  |  |
Warrant exercise price per share |  |  |  |  |  |  |  |  |  |  |  |  |  |  | $ 0.001 |  |  | $ 0.001 |  | $ 0.001 |  | $ 0.001 |  | $ 0.001 |  |
Number of pre-funded warrants exercised for common stock |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 240,000 |  |  | 583,000 |  | 600,000 |  | 653,000 |  | 501,197 |  |
Series X1 Preferred Stock [Member] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Class Of Stock [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Shares of common stock issued upon conversion of each share of preferred stock |  |  |  |  |  |  |  |  |  |  |  | 2,789,301 |  |  |  |  |  |  |  |  |  |  |  |  |  |
Warrants available for exercise |  |  |  |  |  |  |  |  |  |  |  | 50,207.419 |  |  |  |  |  |  |  |  |  |  |  |  |  |
Series X Non-Voting Convertible Preferred Stock [Member] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Class Of Stock [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Preferred stock, shares authorized |  |  |  | 10,000 |  |  |  |  |  |  |  | 10,000 | 10,000 |  |  | 10,000 |  |  | 10,000 |  |  |  |  |  | 10,000 |
Preferred stock, par value |  |  |  | $ 0.001 |  |  |  |  |  |  |  | $ 0.001 | $ 0.001 | $ 0.001 |  | $ 0.001 |  |  | $ 0.001 |  |  |  |  |  | $ 0.001 |
Preferred stock, shares issued |  |  |  | 4,422 |  |  |  |  |  |  |  | 4,422 | 4,422 |  |  | 4,422 |  |  | 4,422 |  |  |  |  |  | 6,204 |
Preferred stock, shares outstanding |  |  |  | 4,422 |  |  |  |  |  |  |  | 4,422 | 4,422 |  |  | 4,422 |  |  | 4,422 |  |  |  |  |  | 6,204 |
Series X1 Non-voting Convertible Preferred Stock [Member] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Class Of Stock [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Preferred stock, shares authorized |  |  |  | 515,000 |  |  |  |  |  |  |  | 515,000 | 515,000 |  |  | 515,000 |  |  | 515,000 |  |  |  |  |  | 515,000 |
Preferred stock, par value |  |  |  | $ 0.001 |  |  |  |  |  |  |  | $ 0.001 | $ 0.001 |  |  | $ 0.001 |  |  | $ 0.001 |  |  |  |  |  | $ 0.001 |
Preferred stock, shares issued |  |  |  | 110,086 |  |  |  |  |  |  |  | 110,086 | 110,086 |  |  | 110,086 |  |  | 110,086 |  |  |  |  |  | 117,970 |
Preferred stock, shares outstanding |  |  |  | 110,086 |  |  |  |  |  |  |  | 110,086 | 110,086 |  |  | 110,086 |  |  | 110,086 |  |  |  |  |  | 117,970 |
Leerink Partners LLC [Member] | Underwriting Agreement[Member] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Class Of Stock [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Proceeds from issuance offering | $ 85,000 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Net proceeds after deducting offering costs | $ 79,500 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Common Stock [Member] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Class Of Stock [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Warrants available for exercise |  |  |  |  |  |  |  |  |  |  |  | 33,052,744 |  |  |  |  |  |  |  |  |  |  |  |  |  |
Common Stock [Member] | Series X Non-Voting Convertible Preferred Stock [Member] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Class Of Stock [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Shares of common stock issued upon conversion of each share of preferred stock |  |  |  |  |  |  |  |  |  |  |  | 55.5556 |  |  |  |  |  |  |  |  |  |  |  |  |  |
Common Stock [Member] | Series X1 Non-voting Convertible Preferred Stock [Member] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Class Of Stock [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Shares of common stock issued upon conversion of each share of preferred stock |  |  |  |  |  |  |  |  |  |  |  | 55.5556 |  |  |  |  |  |  |  |  |  |  |  |  |  |
Common Stock [Member] | Leerink Partners LLC [Member] | Underwriting Agreement[Member] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Class Of Stock [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Conversion of stock, shares issued |  | 18,356,173 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Common stock warrants exercisable |  | 4,931,507 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Warrant exercise price per share |  | $ 0.001 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Stock price per share |  | 3.65 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Warrants [Member] | Leerink Partners LLC [Member] | Underwriting Agreement[Member] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Class Of Stock [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Warrant exercise price per share |  | $ 3.649 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Pre-Funded Warrants [Member] | Accredited Investor [Member] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Class Of Stock [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Class of Warrant Subject to Specified Beneficial Ownership Limitations Percentage |  |  |  |  |  |  |  |  |  | 9.99% |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Common Stock Warrants [Member] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Class Of Stock [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Warrants available for exercise |  |  |  |  |  |  |  |  |  |  |  | 33,052,744 | 21,564,302 |  |  |  |  |  |  |  |  |  |  |  |  |
Common Stock Warrants [Member] | Accredited Investor [Member] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Class Of Stock [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Class of Warrant Subject to Specified Beneficial Ownership Limitations Percentage |  |  |  |  |  |  |  |  |  | 9.99% |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Private Placement Warrants [Member] | Accredited Investor [Member] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Class Of Stock [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Warrant exercise price per share |  |  |  |  |  |  |  |  |  | $ 3 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Private Placement Warrants [Member] | Securities Purchase Agreement [Member] | Accredited Investor [Member] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Class Of Stock [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Conversion of stock, shares issued |  |  |  |  |  |  | 13,110,484 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Net proceeds after deducting offering costs |  |  |  |  |  |  | $ 48,100 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Stock price per share |  |  |  |  |  |  | $ 2.37 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Gross proceeds |  |  |  |  |  |  | $ 50,000 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Private Placement Warrants [Member] | Securities Purchase Agreement Initial Closing [Member] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Class Of Stock [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Common warrants issued |  |  |  |  |  |  |  |  | $ 35,000 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Net proceeds after deducting offering costs |  |  |  |  |  |  |  |  | $ 33,000 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Private Placement Warrants [Member] | Securities Purchase Agreement Initial Closing [Member] | Accredited Investor [Member] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Class Of Stock [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Common stock, shares issued |  |  |  |  |  |  |  |  |  | 15,151,518 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Common stock, par value |  |  |  |  |  |  |  |  |  | $ 0.001 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Common stock warrants exercisable |  |  |  |  |  |  |  |  |  | 15,151,518 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Private Placement Warrants [Member] | Securities Purchase Agreement Second Closing [Member] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Class Of Stock [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Common stock, shares issued |  |  |  |  |  | 909,088 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Proceeds from issuance of common stock |  |  |  |  |  | $ 2,100 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Net proceeds after deducting offering costs |  |  |  |  |  | $ 2,000 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Private Placement Warrants [Member] | Securities Purchase Agreement Second Closing [Member] | Accredited Investor [Member] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Class Of Stock [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Common stock, shares issued |  |  |  |  |  |  |  |  |  | 20,202,024 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Private Placement Warrants [Member] | Securities Purchase Agreement Third Closing [Member] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Class Of Stock [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Common stock, shares issued |  |  | 1,727,400 | 1,727,400 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Proceeds from issuance of common stock |  |  | $ 4,000 | $ 4,000 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Net proceeds after deducting offering costs |  |  | $ 3,800 | $ 3,800 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Private Placement Warrants [Member] | Securities Purchase Agreement Third Closing [Member] | Accredited Investor [Member] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Class Of Stock [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Common stock, shares issued |  |  |  |  |  |  |  |  |  | 25,252,530 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Private Placement Warrants [Member] | Common Stock [Member] | Securities Purchase Agreement Initial Closing [Member] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Class Of Stock [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Common stock, shares issued |  |  |  |  |  |  |  |  | 8,730,168 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Private Placement Warrants [Member] | Pre-Funded Warrants [Member] | Accredited Investor [Member] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Class Of Stock [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Warrant exercise price per share |  |  |  |  |  |  |  |  |  | $ 0.001 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Private Placement Warrants [Member] | Pre-Funded Warrants [Member] | Securities Purchase Agreement [Member] | Accredited Investor [Member] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Class Of Stock [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Common stock warrants exercisable |  |  |  |  |  |  | 7,989,516 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Warrant exercise price per share |  |  |  |  |  |  | $ 0.001 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Stock price per share |  |  |  |  |  |  | $ 2.369 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Private Placement Warrants [Member] | Pre-Funded Warrants [Member] | Securities Purchase Agreement Initial Closing [Member] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Class Of Stock [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Common stock, shares issued |  |  |  |  |  |  |  |  | 6,421,350 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Preferred Stock Warrants [Member] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Class Of Stock [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Warrant exercise price per share |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | $ 8.96
Warrants available for exercise |  |  |  |  |  |  |  |  |  |  |  | 50,207.419 | 50,207.419 |  |  |  |  |  |  |  |  |  |  |  |  |
Expiration Date |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | Sep. 14, 2025
Maximum [Member] | Common Stock [Member] | Series X Non-Voting Convertible Preferred Stock [Member] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Class Of Stock [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Conversion of preferred stock, conversion blocker, percent |  |  |  |  |  |  |  |  |  |  |  | 9.99% |  |  |  |  |  |  |  |  |  |  |  |  |  |
Maximum [Member] | Common Stock [Member] | Series X1 Non-voting Convertible Preferred Stock [Member] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Class Of Stock [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Conversion of preferred stock, conversion blocker, percent |  |  |  |  |  |  |  |  |  |  |  | 9.99% |  |  |  |  |  |  |  |  |  |  |  |  |  |
Maximum [Member] | Pre-Funded Warrants [Member] | Accredited Investor [Member] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Class Of Stock [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Class of Warrant Subject to Specified Beneficial Ownership Limitations Percentage |  |  |  |  |  |  | 9.99% |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Class of Warrant Subject to Specified Beneficial Ownership Limitations Permitted Percentage |  |  |  |  |  |  | 19.99% |  |  | 19.99% |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Maximum [Member] | Pre-Funded Warrants [Member] | Leerink Partners LLC [Member] | Underwriting Agreement[Member] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Class Of Stock [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Class of Warrant Subject to Specified Beneficial Ownership Limitations Percentage |  | 9.99% |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Maximum [Member] | Common Stock Warrants [Member] | Accredited Investor [Member] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Class Of Stock [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Class of Warrant Subject to Specified Beneficial Ownership Limitations Permitted Percentage |  |  |  |  |  |  |  |  |  | 19.99% |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Minimum [Member] | Common Stock [Member] | Series X Non-Voting Convertible Preferred Stock [Member] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Class Of Stock [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Conversion of preferred stock, conversion blocker, percent |  |  |  |  |  |  |  |  |  |  |  | 9.90% |  |  |  |  |  |  |  |  |  |  |  |  |  |
Minimum [Member] | Common Stock [Member] | Series X1 Non-voting Convertible Preferred Stock [Member] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Class Of Stock [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Conversion of preferred stock, conversion blocker, percent |  |  |  |  |  |  |  |  |  |  |  | 9.90% |  |  |  |  |  |  |  |  |  |  |  |  |  |
Minimum [Member] | Pre-Funded Warrants [Member] | Accredited Investor [Member] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Class Of Stock [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Class of Warrant Subject to Specified Beneficial Ownership Limitations Percentage |  |  |  |  |  |  | 4.99% |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Minimum [Member] | Pre-Funded Warrants [Member] | Leerink Partners LLC [Member] | Underwriting Agreement[Member] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Class Of Stock [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Class of Warrant Subject to Specified Beneficial Ownership Limitations Percentage |  | 4.99% |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
BVF Exchanging Stockholders [Member] | Series X1 Non-voting Convertible Preferred Stock [Member] | Series X1 Exchange Agreement [Member] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Class Of Stock [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Conversion of stock, shares issued |  |  |  |  |  |  |  |  |  |  | 9,899.99 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
BVF Exchanging Stockholders [Member] | Common Stock [Member] | Series X1 Exchange Agreement [Member] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Class Of Stock [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Conversion of stock, shares converted |  |  |  |  |  |  |  |  |  |  | 550,000 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Cormorant Global Healthcare Master Fund LP [Member] | Series X Non-Voting Convertible Preferred Stock [Member] | Conversion Agreement [Member] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Class Of Stock [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Conversion of stock, shares converted |  |  |  |  |  |  |  | 1,782 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Cormorant Global Healthcare Master Fund LP [Member] | Series X1 Non-voting Convertible Preferred Stock [Member] | Conversion Agreement [Member] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Class Of Stock [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Conversion of stock, shares converted |  |  |  |  |  |  |  | 7,883.586 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Cormorant Global Healthcare Master Fund LP [Member] | Common Stock [Member] | Series X Non-Voting Convertible Preferred Stock [Member] | Conversion Agreement [Member] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Class Of Stock [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Conversion of stock, shares issued |  |  |  |  |  |  |  | 99,000 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Cormorant Global Healthcare Master Fund LP [Member] | Common Stock [Member] | Series X1 Non-voting Convertible Preferred Stock [Member] | Conversion Agreement [Member] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Class Of Stock [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Conversion of stock, shares issued |  |  |  |  |  |  |  | 437,977 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Guggenheim Securities LLC [Member] | Maximum [Member] | Equity Distribution Agreement [Member] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Class Of Stock [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Proceeds from issuance of common stock |  |  |  |  | $ 75,000 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |

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