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Stockholders' Equity - Additional Information (Detail) - USD ($)
 3 Months Ended
Oct. 30, 2024
Oct. 29, 2024
Oct. 01, 2024
Sep. 30, 2024
Sep. 20, 2024
Jul. 08, 2024
May 06, 2024
May 05, 2023
Apr. 28, 2023
Mar. 31, 2025
Mar. 31, 2024
Dec. 31, 2024
Jul. 11, 2024
May 09, 2024
May 07, 2024
Jan. 30, 2024
Nov. 06, 2023
Nov. 02, 2023
Jul. 14, 2023
Jul. 10, 2023
Class Of Stock [Line Items]                                        
Debt outstanding                   $ 0                    
Common stock, shares issued                   59,881,775   59,789,275                
Common stock par value                   $ 0.001   $ 0.001                
Net proceeds after deducting offering costs                     $ 1,000                  
Preferred stock, shares authorized                   5,000,000   5,000,000                
Preferred stock, par value                   $ 0.001   $ 0.001                
Underwriting Agreement [Member] | Leerink Partners LLC [Member]                                        
Class Of Stock [Line Items]                                        
Proceeds from issuance offering $ 85,000,000                                      
Net proceeds after deducting offering costs $ 79,500,000                                      
Armistice Capital Master Fund Ltd [Member] | Securities Purchase Agreement [Member]                                        
Class Of Stock [Line Items]                                        
Number of pre-funded warrants exercised for common stock                         240,000   583,000 600,000   653,000   501,197
Common stock, shares issued                         240,000 583,000   600,000 653,000   501,197  
Warrant exercise price per share                         $ 0.001   $ 0.001 $ 0.001   $ 0.001   $ 0.001
Series X1 Preferred Stock [Member]                                        
Class Of Stock [Line Items]                                        
Warrants available for exercise                   50,207.419                    
Shares of common stock issued upon conversion of each share of preferred stock                   2,789,301                    
Series X1 Non-voting Convertible Preferred Stock [Member]                                        
Class Of Stock [Line Items]                                        
Preferred stock, shares authorized                   515,000   515,000                
Preferred stock, par value                   $ 0.001   $ 0.001                
Preferred stock, shares outstanding                   110,086   110,086                
Preferred stock, shares issued                   110,086   110,086                
Series X Non-Voting Convertible Preferred Stock [Member]                                        
Class Of Stock [Line Items]                                        
Preferred stock, shares authorized                   10,000   10,000                
Preferred stock, par value                   $ 0.001   $ 0.001                
Preferred stock, shares outstanding                   4,422   4,422                
Preferred stock, shares issued                   4,422   4,422                
Common Stock [Member]                                        
Class Of Stock [Line Items]                                        
Warrants available for exercise                   33,052,744                    
Common Stock [Member] | Underwriting Agreement [Member] | Leerink Partners LLC [Member]                                        
Class Of Stock [Line Items]                                        
Conversion of stock, shares issued   18,356,173                                    
Stock price per share   $ 3.65                                    
Common stock warrants exercisable   4,931,507                                    
Warrant exercise price per share   $ 0.001                                    
Common Stock [Member] | Series X1 Non-voting Convertible Preferred Stock [Member]                                        
Class Of Stock [Line Items]                                        
Shares of common stock issued upon conversion of each share of preferred stock                   55.5556                    
Common Stock [Member] | Series X Non-Voting Convertible Preferred Stock [Member]                                        
Class Of Stock [Line Items]                                        
Shares of common stock issued upon conversion of each share of preferred stock                   55.5556                    
Warrants [Member] | Underwriting Agreement [Member] | Leerink Partners LLC [Member]                                        
Class Of Stock [Line Items]                                        
Warrant exercise price per share   $ 3.649                                    
Pre-funded Warrants [Member] | Accredited Investor [Member]                                        
Class Of Stock [Line Items]                                        
Class of Warrant Subject to Specified Beneficial Ownership Limitations Percentage                 9.99%                      
Common Stock Warrants [Member]                                        
Class Of Stock [Line Items]                                        
Warrants available for exercise                   33,052,744   33,052,744                
Common Stock Warrants [Member] | Accredited Investor [Member]                                        
Class Of Stock [Line Items]                                        
Class of Warrant Subject to Specified Beneficial Ownership Limitations Percentage                 9.99%                      
Private Placement Warrants [Member] | Accredited Investor [Member]                                        
Class Of Stock [Line Items]                                        
Warrant exercise price per share                 $ 3                      
Private Placement Warrants [Member] | Securities Purchase Agreement [Member] | Accredited Investor [Member]                                        
Class Of Stock [Line Items]                                        
Common stock, shares issued             13,110,484                          
Stock price per share             $ 2.37                          
Gross proceeds             $ 50,000,000                          
Net proceeds after deducting offering costs             $ 48,100,000                          
Private Placement Warrants [Member] | Securities Purchase Agreement Initial Closing [Member]                                        
Class Of Stock [Line Items]                                        
Common warrants issued               $ 35,000,000                        
Net proceeds after deducting offering costs               $ 33,000,000                        
Private Placement Warrants [Member] | Securities Purchase Agreement Initial Closing [Member] | Accredited Investor [Member]                                        
Class Of Stock [Line Items]                                        
Common stock, shares issued                 15,151,518                      
Common stock par value                 $ 0.001                      
Common stock warrants exercisable                 15,151,518                      
Private Placement Warrants [Member] | Securities Purchase Agreement Second Closing [Member]                                        
Class Of Stock [Line Items]                                        
Common stock, shares issued           909,088                            
Proceeds from issuance of common stock           $ 2,100,000                            
Net proceeds after deducting offering costs           $ 2,000,000                            
Private Placement Warrants [Member] | Securities Purchase Agreement Second Closing [Member] | Accredited Investor [Member]                                        
Class Of Stock [Line Items]                                        
Common stock, shares issued                 20,202,024                      
Private Placement Warrants [Member] | Securities Purchase Agreement Third Closing [Member]                                        
Class Of Stock [Line Items]                                        
Common stock, shares issued     1,727,400 1,727,400                                
Proceeds from issuance of common stock     $ 4,000,000 $ 4,000,000                                
Net proceeds after deducting offering costs     $ 3,800,000 $ 3,800,000                                
Private Placement Warrants [Member] | Securities Purchase Agreement Third Closing [Member] | Accredited Investor [Member]                                        
Class Of Stock [Line Items]                                        
Common stock, shares issued                 25,252,530                      
Private Placement Warrants [Member] | Common Stock [Member] | Securities Purchase Agreement Initial Closing [Member]                                        
Class Of Stock [Line Items]                                        
Common stock, shares issued               8,730,168                        
Private Placement Warrants [Member] | Pre-funded Warrants [Member] | Accredited Investor [Member]                                        
Class Of Stock [Line Items]                                        
Warrant exercise price per share                 $ 0.001                      
Private Placement Warrants [Member] | Pre-funded Warrants [Member] | Securities Purchase Agreement [Member] | Accredited Investor [Member]                                        
Class Of Stock [Line Items]                                        
Stock price per share             $ 2.369                          
Common stock warrants exercisable             7,989,516                          
Warrant exercise price per share             $ 0.001                          
Private Placement Warrants [Member] | Pre-funded Warrants [Member] | Securities Purchase Agreement Initial Closing [Member]                                        
Class Of Stock [Line Items]                                        
Common stock, shares issued               6,421,350                        
Maximum [Member] | Common Stock [Member] | Series X1 Non-voting Convertible Preferred Stock [Member]                                        
Class Of Stock [Line Items]                                        
Conversion of preferred stock, conversion blocker, percent                   9.99%                    
Maximum [Member] | Common Stock [Member] | Series X Non-Voting Convertible Preferred Stock [Member]                                        
Class Of Stock [Line Items]                                        
Conversion of preferred stock, conversion blocker, percent                   9.99%                    
Maximum [Member] | Pre-funded Warrants [Member] | Accredited Investor [Member]                                        
Class Of Stock [Line Items]                                        
Class of Warrant Subject to Specified Beneficial Ownership Limitations Percentage             9.99%                          
Class of Warrant Subject to Specified Beneficial Ownership Limitations Permitted Percentage             19.99%   19.99%                      
Maximum [Member] | Pre-funded Warrants [Member] | Underwriting Agreement [Member] | Leerink Partners LLC [Member]                                        
Class Of Stock [Line Items]                                        
Class of Warrant Subject to Specified Beneficial Ownership Limitations Percentage   9.99%                                    
Maximum [Member] | Common Stock Warrants [Member] | Accredited Investor [Member]                                        
Class Of Stock [Line Items]                                        
Class of Warrant Subject to Specified Beneficial Ownership Limitations Permitted Percentage                 19.99%                      
Minimum [Member] | Common Stock [Member] | Series X1 Non-voting Convertible Preferred Stock [Member]                                        
Class Of Stock [Line Items]                                        
Conversion of preferred stock, conversion blocker, percent                   9.90%                    
Minimum [Member] | Common Stock [Member] | Series X Non-Voting Convertible Preferred Stock [Member]                                        
Class Of Stock [Line Items]                                        
Conversion of preferred stock, conversion blocker, percent                   9.90%                    
Minimum [Member] | Pre-funded Warrants [Member] | Accredited Investor [Member]                                        
Class Of Stock [Line Items]                                        
Class of Warrant Subject to Specified Beneficial Ownership Limitations Percentage             4.99%                          
Minimum [Member] | Pre-funded Warrants [Member] | Underwriting Agreement [Member] | Leerink Partners LLC [Member]                                        
Class Of Stock [Line Items]                                        
Class of Warrant Subject to Specified Beneficial Ownership Limitations Percentage   4.99%                                    
Guggenheim Securities LLC [Member] | Maximum [Member] | Equity Distribution Agreement [Member]                                        
Class Of Stock [Line Items]                                        
Proceeds from issuance of common stock         $ 75,000,000