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Summary of Significant Accounting Policies - Schedule of significant segment expenses (Detail) - USD ($)
$ in Thousands
 3 Months Ended 6 Months Ended
Jun. 30, 2025
Mar. 31, 2025
Jun. 30, 2024
Mar. 31, 2024
Jun. 30, 2025
Jun. 30, 2024
Segment Reporting Information [Line Items]            
Total operating expenses $ 24,733   $ 14,502   $ 42,697 $ 25,371
Loss from operations (24,733)   (14,502)   (42,697) (25,371)
Other income, net 1,224   869   2,633 1,443
Change in fair value of warrant liabilities 12,293   (31,274)   22,353 (44,610)
Net loss (11,216) $ (6,495) (44,907) $ (23,631) (17,711) (68,538)
Operating Segments [Member]            
Segment Reporting Information [Line Items]            
Tegoprubart - kidney transplantation programs 8,705   4,620   17,237 9,117
Tegoprubart - other development programs     345   (168) 416
Manufacturing 7,626   2,797   9,295 3,574
Personnel-related 3,697   2,350   7,144 4,875
Stock-based compensation 2,694   3,063   5,558 4,757
Other operating expenses 2,011   1,327   3,631 2,632
Total operating expenses 24,733   14,502   42,697 25,371
Loss from operations (24,733)   (14,502)   (42,697) (25,371)
Other income, net 1,224   869   2,633 1,443
Change in fair value of warrant liabilities 12,293   (31,274)   22,353 (44,610)
Net loss $ (11,216)   $ (44,907)   $ (17,711) $ (68,538)