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v3.7.0.1

Statements Of Cash Flows - USD ($) $ in Thousands | 12 Months Ended
--- | ---
Dec. 31, 2016 | Dec. 31, 2015 | Dec. 31, 2014
Cash flows used in operating activities: |  |  |
Net loss | $ (14,850) | $ (14,145) | $ (12,386)
Adjustments to reconcile net loss to net cash used in operating activities: |  |  |
Non-cash stock-based compensation | 4,334 | 3,457 | 3,761
Depreciation and amortization | 58 | 45 | 15
Non-cash net interest income | (8) | (4) | (2)
Changes in operating assets and liabilities: |  |  |
Other current assets | 86 | (87) | 26
Other non-current assets | 12 |  | (12)
Accounts payable | (711) | 841 | (272)
Accrued development expense | (867) | 869 | (616)
Accrued compensation and benefits | (288) | (29) | (60)
Other current liabilities |  |  | (3)
Net cash used in operating activities | (12,234) | (9,053) | (9,549)
Cash flows provided by (used in) investing activities: |  |  |
Purchases of property and equipment | (75) | (195) | (80)
Purchases of marketable securities | (4,141) | (3,847) | (2,598)
Maturities of marketable securities | 2,050 | 3,850 | 3,850
Net cash provided by (used in) investing activities | (2,166) | (192) | 1,172
Cash flows provided by (used in) financing activities: |  |  |
Proceeds from issuance of common stock, net |  |  | 379
Statutory taxes for net exercise of Performance Awards | (214) |  |
Deferred financing costs | (70) | (46) |
Net cash provided by (used in) financing activities | (284) | (46) | 379
Net decrease in cash and cash equivalents | (14,684) | (9,291) | (7,998)
Cash and cash equivalents at beginning of the period | 31,299 | 40,590 | 48,588
Cash and cash equivalents at end of the period | $ 16,615 | $ 31,299 | $ 40,590

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