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Collaboration Agreements	12 Months Ended
Collaboration Agreements	Dec. 31, 2016
Collaboration Agreements [Abstract]
Collaboration Agreements	3. Collaboration Agreements Durect Corporation We have an exclusive, worldwide Development and License Agreement, or the Durect Agreement, with Durect to use a patented controlled-release technology that forms the basis for REMOXY. Under the terms of the Durect Agreement, we are solely responsible for clinical development, Durect is responsible for furnishing suitable laboratory facilities, equipment and personnel during pre-clinical phases of development and we and Durect are jointly responsible for certain pre-clinical activities. We reimburse Durect’s expenses and have made milestone payments based on the achievement of certain clinical or regulatory milestones.