The Company has a non-cancelable operating lease for approximately 6,000 square feet of office space in Austin, Texas that expires on April 30, 2024. The Company also has a short-term lease agreement for an additional 3,600 square feet of office space in Austin, Texas that, as amended in April 2022, expires on October 31, 2022. Future lease payments as of March 31, 2022 are as follows (in thousands):


		2022	2023	2024	Total future lease payments	Less: imputed interest		Total

Operating leases	$	77	107	36	220	(7)	$	213
Short-term operating lease	$	37	—	—	37	—	$	37

Rent expense for the three months ended March 31, 2022 and 2021 totaled $41,000 and $23,000, respectively.

Cash paid for operating lease liabilities during the three months ended March 31, 2022 totaled $41,000. There was no cash paid for operating lease liabilities during the three months ended March 31, 2021.

The Company conducts its product research and development programs through a combination of internal and collaborative programs that include, among others, arrangements with universities, contract research organizations and clinical research sites. The Company has contractual arrangements with these organizations that are cancelable. The Company’s obligations under these contracts are largely based on services performed.