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Condensed Consolidated Statements Of Cash Flows - USD ($)
 3 Months Ended
Mar. 31, 2023
Mar. 31, 2022
Cash flows from operating activities:    
Net loss $ (24,271,000) $ (17,527,000)
Adjustments to reconcile net loss to net cash used in operating activities:    
Stock-based compensation 673,000 495,000
Depreciation 272,000 178,000
Amortization of intangible assets 119,000 135,000
Changes in operating assets and liabilities:    
Prepaid and other current assets 2,679,000 (1,063,000)
Operating lease right-of-use assets and liabilities (17,000) (1,000)
Accounts payable and accrued expenses 4,565,000 (3,794,000)
Accrued development expense 2,996,000 122,000
Accrued compensation and benefits 42,000 (1,705,000)
Other liabilities (313,000) (370,000)
Net cash used in operating activities (13,255,000) (23,530,000)
Cash flows from investing activities:    
Purchases of property and equipment (357,000) (425,000)
Net cash used in investing activities (357,000) (425,000)
Cash flows from financing activities:    
Proceeds from issuance of common stock upon exercise of stock options 64,000 211,000
Net cash provided by financing activities 64,000 211,000
Net decrease in cash and cash equivalents (13,548,000) (23,744,000)
Cash and cash equivalents at beginning of period 201,015,000 233,437,000
Cash and cash equivalents at end of period $ 187,467,000 $ 209,693,000