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Note 2 - Summary of Significant Accounting Policies (Tables) | 12 Months Ended
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Dec. 31, 2024
Notes Tables |
Fair Value Measurement Inputs and Valuation Techniques [Table Text Block] |
Exercise price per warrant |  | $ | 33.00 |
Conversion rate - common shares per warrant |  |  | 1.50 |
Closing price of common stock |  | $ | 23.72 |
Volatility |  |  | 75 | %
Risk-free interest rate |  |  | 5.40 | %
Expected life of option (in years) |  |  | 0.3 |
Dividend yield |  | zero |
Schedule of Segment Reporting Information, by Segment [Table Text Block] |
|  | Years Ended December 31, |
|  | 2024 |  |  | 2023 |  |  | 2022 |
Operating expenses |  |  |  |  |  |  |  |  |  |  |  |
Research and development |  | $ | 69,637 |  |  | $ | 89,423 |  |  | $ | 68,032 |
General and administrative |  |  | 71,809 |  |  |  | 16,534 |  |  |  | 11,988 |
Other segment items(a) |  |  | (117,104 | ) |  |  | (8,740 | ) |  |  | (3,774 | )
Net loss |  | $ | 24,342 |  |  | $ | 97,217 |  |  | $ | 76,246 |
|  | December 31, |
|  | 2024 |  |  | 2023 |
Cash and cash equivalents |  | $ | 128,574 |  |  | $ | 121,136 |
Schedule of Earnings Per Share, Basic and Diluted [Table Text Block] |
|  | Years ended December 31, |
|  | 2024 |  |  | 2023 |  |  | 2022 |
Numerator, basic: |  |  |  |  |  |  |  |  |  |  |  |
Net loss |  | $ | (24,342 | ) |  | $ | (97,217 | ) |  | $ | (76,246 | )
Denominator, basic: |  |  |  |  |  |  |  |  |  |  |  |
Weighted average common shares outstanding |  |  | 46,329 |  |  |  | 41,932 |  |  |  | 40,202 |
Net loss per share, basic |  |  | (0.53 | ) |  |  | (2.32 | ) |  |  | (1.90 | )
Numerator, diluted: |  |  |  |  |  |  |  |  |  |  |  |
Net loss |  | $ | (24,342 | ) |  | $ | (97,217 | ) |  | $ | (76,246 | )
Adjustment for change in fair value of warrant liabilities |  |  | (43,793 | ) |  |  | — |  |  |  | — |
Adjusted numerator, diluted |  | $ | (68,135 | ) |  | $ | (97,217 | ) |  | $ | (76,246 | )
Denominator, diluted: |  |  |  |  |  |  |  |  |  |  |  |
Weighted average common shares outstanding |  |  | 46,329 |  |  |  | 41,932 |  |  |  | 40,202 |
Dilutive effect of common stock warrants |  |  | 275 |  |  |  | — |  |  |  | — |
Weighted average dilutive common shares |  |  | 46,604 |  |  |  | 41,932 |  |  |  | 40,202 |
Net loss per share, diluted |  | $ | (1.46 | ) |  | $ | (2.32 | ) |  | $ | (1.90 | )
Dilutive common stock options excluded from net loss per share, diluted |  |  | 3,154 |  |  |  | 2,123 |  |  |  | 2,055 |
Dilutive Performance Awards excluded from loss per share, diluted |  |  | 7 |  |  |  | 7 |  |  |  | 7 |

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