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Note 7 - Stockholders' Equity and Stock-based Compensation (Tables)

12 Months Ended

Dec. 31, 2024

Notes Tables

Share-Based Payment Arrangement, Option, Activity [Table Text Block]

						Weighted Average				Weighted Average
		Number of				Weighted Average				Remaining Contractual				Aggregate Intrinsic Value
		Options				Exercise Price				Term in Years				in Millions
Outstanding as of December 31, 2023			3,039,029			$	15.13				6.21			$	30.28
Options granted			2,083,000				26.65
Options exercised			(240,147	)			5.25
Options forfeited/canceled			(418,854	)			24.64
Outstanding as of December 31, 2024			4,463,028				20.15				7.61			$	0.30
Vested and expected to vest at December 31, 2024			3,965,665				19.93				7.44			$	0.30
Exercisable at December 31, 2024			1,794,501			$	12.86				4.95			$	0.30

Share-Based Payment Arrangement, Option, Exercise Price Range [Table Text Block]

								Options outstanding												Options exercisable
												Weighted
												average				Weighted								Weighted
								Number of				remaining				average				Number of				average
Range of exercise prices								outstanding				contractual				exercise				vested				exercise
From				To				options				life (in years)				price				options				price
$	0.95			$	4.10				900,303				3.5			$	2.80				900,303			$	2.80
$	5.46			$	17.54				1,049,656				7.1			$	16.21				560,765			$	15.06
$	18.78			$	26.57				539,277				8.7			$	21.90				197,198			$	21.81
$	26.91			$	26.91				1,080,000				9.7			$	26.91				364			$	26.91
$	27.42			$	77.00				893,792				9.2			$	33.02				135,871			$	57.40
									4,463,028				7.6			$	20.15				1,794,501			$	12.86

Schedule of Share-Based Payment Award, Stock Options, Valuation Assumptions [Table Text Block]

		2024				2023				2022
Volatility			151% to 170%				152% to 155%				151% to 154%
Risk-free interest rates			3.53% to 4.47%				3.82% to 4.37%				1.98% to 3.69%
Expected life of option (in years)			7				7				7
Dividend yield		zero				zero				zero
Forfeiture rate		4.3		%		zero				zero
Weighted average fair value of stock options granted		$	25.85			$	18.21			$	35.16

Share-Based Payment Arrangement, Activity [Table Text Block]

		Number of Performance Awards
Outstanding as of December 31, 2023			7,142
Granted			—
Vested			—
Forfeited/canceled			—
Outstanding as of December 31, 2024			7,142

Share-Based Payment Arrangement, Expensed and Capitalized, Amount [Table Text Block]

		Years ended December 31,
		2024				2023				2022
Research and development		$	6,492			$	2,050			$	1,631
General and administrative			9,799				2,536				435
Total stock-based compensation expense		$	16,291			$	4,586			$	2,066

X

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