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Note 6 - Stockholders' Equity and Stock-based Compensation Expense (Tables)
6 Months Ended
Jun. 30, 2025
Notes Tables  
Share-Based Payment Arrangement, Activity [Table Text Block]
  

Stock Options

  

Performance Awards

 

Outstanding as of December 31, 2024

  4,463,028   7,142 

Options granted

  1,467,000    

Options exercised

  (225,209)   

Options forfeited/canceled

  (1,359,449)   

Outstanding as of June 30, 2025

  4,345,370   7,142 
Share-Based Payment Arrangement, Expensed and Capitalized, Amount [Table Text Block]
  

Three months ended

  

Six months ended

 
  

June 30,

  

June 30,

 
  

2025

  

2024

  

2025

  

2024

 

Research and development

 $1,162  $972  $3,534  $1,945 

General and administrative

  3,420   1,632   6,272   2,994 

Total stock-based compensation expense

 $4,582  $2,604  $9,806  $4,939