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Note 7 - Stockholders' Equity and Stock-based Compensation - Stock-based Compensation Expense (Details) - USD ($) $ in Thousands | 12 Months Ended
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Dec. 31, 2025 | Dec. 31, 2024 | Dec. 31, 2023
Total stock-based compensation expense | $ 19,582 | $ 16,291 | $ 4,586
Research and Development Expense [Member] |  |  |
Total stock-based compensation expense | 7,159 | 6,492 | 2,050
General and Administrative Expense [Member] |  |  |
Total stock-based compensation expense | $ 12,423 | $ 9,799 | $ 2,536

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