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Note 2 - Summary of Significant Accounting Policies (Details Textual) $ / shares in Units, shares in Thousands |  |  | 12 Months Ended |  |  |  |
--- | --- | --- | --- | --- | --- | --- | ---
Jul. 16, 2024 USD ($) | Jul. 15, 2024 USD ($) | Dec. 31, 2025 USD ($) shares | Dec. 31, 2024 USD ($) shares | Dec. 31, 2023 USD ($) | Jun. 20, 2025 | May 07, 2024 $ / shares | Jan. 03, 2024 $ / shares | Jan. 02, 2024 shares
Class of Warrant or Right, Fair Value of Common Stock Warrants per Warrant (in dollars per share) | $ / shares |  |  |  |  |  |  |  | $ 6.71 |
Class of Warrant or Right, Redemption Price per Share (in dollars per share) | $ / shares |  |  |  |  |  |  | $ 0.001 |  |
Number of Operating Segments |  |  | 1 |  |  |  |  |  |
Number of Reportable Segments |  |  | 1 |  |  |  |  |  |
Cash Provided by (Used in) Operating Activity, Including Discontinued Operation |  |  | $ (32,252,000) | $ (116,929,000) | $ (82,025,000) |  |  |  |
Class of Warrant or Right, Outstanding (in shares) | shares |  |  | 0 | 0 |  |  |  |  | 16,895
Proceeds from Insurance Settlement, Operating Activities |  |  | $ 0 | $ 9,900,000 | $ 100,000 |  |  |  |
Former Senior Vice President [Member] |  |  |  |  |  |  |  |  |
Consulting Agreement, Term | 1 |  |  |  |  |  |  |  |
Related Party Transaction, Amounts of Transaction |  |  | 20,000 | 43,000 |  |  |  |  |
Former Chief Medical Officer [Member] |  |  |  |  |  |  |  |  |
Consulting Agreement, Term |  |  |  |  |  | 1 |  |  |
Consulting Agreement, Fixed Fee |  |  | 42,000 |  |  |  |  |  |
Former President and Chief Executive Officer [Member] |  |  |  |  |  |  |  |  |
Severance Costs |  | $ 1,230,000 | 0 |  |  |  |  |  |
Former Senior Vice President [Member] |  |  |  |  |  |  |  |  |
Severance Costs | $ 500,000 |  | 0 |  |  |  |  |  |
Former Senior Officer [Member] |  |  |  |  |  |  |  |  |
Severance Costs |  |  | $ 0 | $ 1,200,000 |  |  |  |  |
Number of Former Employees |  |  | 2 | 2 |  |  |  |  |
Building [Member] |  |  |  |  |  |  |  |  |
Property, Plant and Equipment, Useful Life (Year) |  |  | 39 years |  |  |  |  |  |
Building Improvements [Member] |  |  |  |  |  |  |  |  |
Property, Plant and Equipment, Useful Life (Year) |  |  | 10 years |  |  |  |  |  |
Share-Based Payment Arrangement, Option [Member] | Minimum [Member] |  |  |  |  |  |  |  |  |
Share-Based Compensation Arrangement by Share-Based Payment Award, Award Vesting Period (Year) |  |  | 1 year |  |  |  |  |  |
Share-Based Payment Arrangement, Option [Member] | Maximum [Member] |  |  |  |  |  |  |  |  |
Share-Based Compensation Arrangement by Share-Based Payment Award, Award Vesting Period (Year) |  |  | 4 years |  |  |  |  |  |

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