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Note 2 - Summary of Significant Accounting Policies (Details Textual) $ / shares in Units, shares in Thousands			12 Months Ended
	Jul. 16, 2024 USD ($)	Jul. 15, 2024 USD ($)	Dec. 31, 2025 USD ($) shares	Dec. 31, 2024 USD ($) shares	Dec. 31, 2023 USD ($)	Jun. 20, 2025	May 07, 2024 $ / shares	Jan. 03, 2024 $ / shares	Jan. 02, 2024 shares
Class of Warrant or Right, Fair Value of Common Stock Warrants per Warrant (in dollars per share) | $ / shares								$ 6.71
Class of Warrant or Right, Redemption Price per Share (in dollars per share) | $ / shares							$ 0.001
Number of Operating Segments			1
Number of Reportable Segments			1
Cash Provided by (Used in) Operating Activity, Including Discontinued Operation			$ (32,252,000)	$ (116,929,000)	$ (82,025,000)
Class of Warrant or Right, Outstanding (in shares) | shares			0	0					16,895
Proceeds from Insurance Settlement, Operating Activities			$ 0	$ 9,900,000	$ 100,000
Former Senior Vice President [Member]
Consulting Agreement, Term	1
Related Party Transaction, Amounts of Transaction			20,000	43,000
Former Chief Medical Officer [Member]
Consulting Agreement, Term						1
Consulting Agreement, Fixed Fee			42,000
Former President and Chief Executive Officer [Member]
Severance Costs		$ 1,230,000	0
Former Senior Vice President [Member]
Severance Costs	$ 500,000		0
Former Senior Officer [Member]
Severance Costs			$ 0	$ 1,200,000
Number of Former Employees			2	2
Building [Member]
Property, Plant and Equipment, Useful Life (Year)			39 years
Building Improvements [Member]
Property, Plant and Equipment, Useful Life (Year)			10 years
Share-Based Payment Arrangement, Option [Member] | Minimum [Member]
Share-Based Compensation Arrangement by Share-Based Payment Award, Award Vesting Period (Year)			1 year
Share-Based Payment Arrangement, Option [Member] | Maximum [Member]
Share-Based Compensation Arrangement by Share-Based Payment Award, Award Vesting Period (Year)			4 years

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