    <SEC-DOCUMENT>0001104659-21-130769-index.html : 20211028
    <SEC-HEADER>0001104659-21-130769.hdr.sgml : 20211028
    <ACCEPTANCE-DATETIME>20211028092815
    ACCESSION NUMBER:		0001104659-21-130769
    CONFORMED SUBMISSION TYPE:	S-1/A
    PUBLIC DOCUMENT COUNT:		21
    FILED AS OF DATE:		20211028
    DATE AS OF CHANGE:		20211028

    FILER:

    	COMPANY DATA:
    		COMPANY CONFORMED NAME:			Nuvectis Pharma, Inc.
    		CENTRAL INDEX KEY:			0001875558
    		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
    		IRS NUMBER:				862405608
    		STATE OF INCORPORATION:			DE

    	FILING VALUES:
    		FORM TYPE:		S-1/A
    		SEC ACT:		1933 Act
    		SEC FILE NUMBER:	333-260099
    		FILM NUMBER:		211355526

    	BUSINESS ADDRESS:
    		STREET 1:		1 BRIDGE PLAZA, SUITE 275
    		CITY:			FORT LEE
    		STATE:			NJ
    		ZIP:			07024
    		BUSINESS PHONE:		360-837-7232

    	MAIL ADDRESS:
    		STREET 1:		1 BRIDGE PLAZA, SUITE 275
    		CITY:			FORT LEE
    		STATE:			NJ
    		ZIP:			07024
    </SEC-HEADER>
    <DOCUMENT>
    <TYPE>S-1/A
    <SEQUENCE>1
    <FILENAME>tm2123577-11_s1a.htm
    <DESCRIPTION>S-1/A
    <TEXT>
    Document 1 - file: tm2123577-11_s1a.htm

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>EX-1.1
    <SEQUENCE>2
    <FILENAME>tm2123577d12_ex1-1.htm
    <DESCRIPTION>EXHIBIT 1.1
    <TEXT>
    Document 2 - file: tm2123577d12_ex1-1.htm

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>EX-4.2
    <SEQUENCE>3
    <FILENAME>tm2123577d12_ex4-2.htm
    <DESCRIPTION>EXHIBIT 4.2
    <TEXT>
    Document 3 - file: tm2123577d12_ex4-2.htm

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>EX-10.2
    <SEQUENCE>4
    <FILENAME>tm2123577d12_ex10-2.htm
    <DESCRIPTION>EXHIBIT 10.2
    <TEXT>
    Document 4 - file: tm2123577d12_ex10-2.htm

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>EX-10.3
    <SEQUENCE>5
    <FILENAME>tm2123577d12_ex10-3.htm
    <DESCRIPTION>EXHIBIT 10.3
    <TEXT>
    Document 5 - file: tm2123577d12_ex10-3.htm

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>EX-10.4
    <SEQUENCE>6
    <FILENAME>tm2123577d12_ex10-4.htm
    <DESCRIPTION>EXHIBIT 10.4
    <TEXT>
    Document 6 - file: tm2123577d12_ex10-4.htm

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>EX-23.1
    <SEQUENCE>7
    <FILENAME>tm2123577d12_ex23-1.htm
    <DESCRIPTION>EXHIBIT 23.1
    <TEXT>
    Document 7 - file: tm2123577d12_ex23-1.htm

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>8
    <FILENAME>lg_nuvectispharma-4clr.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 8 - file: lg_nuvectispharma-4clr.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>9
    <FILENAME>lg_pwc-4c.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 9 - file: lg_pwc-4c.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>10
    <FILENAME>tm2123577d1-fc_1fig4clr.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 10 - file: tm2123577d1-fc_1fig4clr.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>11
    <FILENAME>tm2123577d1-fc_2fig4c.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 11 - file: tm2123577d1-fc_2fig4c.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>12
    <FILENAME>tm2123577d1-lc_4fig4clr.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 12 - file: tm2123577d1-lc_4fig4clr.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>13
    <FILENAME>tm2123577d1-org_5fig4clr.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 13 - file: tm2123577d1-org_5fig4clr.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>14
    <FILENAME>tm2123577d1-pht_6fig4clr.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 14 - file: tm2123577d1-pht_6fig4clr.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>15
    <FILENAME>tm2123577d1-tbl_4fig4clr.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 15 - file: tm2123577d1-tbl_4fig4clr.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>16
    <FILENAME>tm2123577d12_ex23-1img001.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 16 - file: tm2123577d12_ex23-1img001.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>17
    <FILENAME>tm2123577d2-fc_target4clr.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 17 - file: tm2123577d2-fc_target4clr.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>18
    <FILENAME>tm2123577d2-lc_potent4clr.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 18 - file: tm2123577d2-lc_potent4clr.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>19
    <FILENAME>tm2123577d2-lc_tumor4clr.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 19 - file: tm2123577d2-lc_tumor4clr.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>20
    <FILENAME>tm2123577d2-pht_inhibit4clr.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 20 - file: tm2123577d2-pht_inhibit4clr.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>21
    <FILENAME>tm2123577d5-tbl_nuvectis4c.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 21 - file: tm2123577d5-tbl_nuvectis4c.jpg

    </DOCUMENT>
    </SEC-DOCUMENT>