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Leases - Additional Information (Details) - USD ($) $ in Thousands | 1 Months Ended | 12 Months Ended |
--- | --- | --- | ---
Aug. 31, 2022 | Oct. 31, 2021 | Jul. 31, 2021 | Jan. 31, 2021 | May 31, 2020 | May 31, 2018 | Dec. 31, 2022 | Dec. 31, 2021
Lessee Lease Description [Line Items] |  |  |  |  |  |  |  |
Weighted-average discount rate |  |  |  |  |  |  | 9.80% |
Right-of-use assets obtained in exchange for operating lease liabilities resulting from new leases |  |  |  |  |  |  | $ 59,500 |
Right-of-use assets obtained in exchange for operating lease liabilities resulting from modifications of existing leases |  |  |  |  |  |  | 18,700 |
Lessee, operating lease, term of contract |  |  | 12 years |  |  |  |  |
Cash received for tenant improvement allowances to be repaid |  |  | $ 4,400 |  |  |  |  |
Lease liabilities |  |  |  |  |  |  | 82,934 |
Right-of-use assets |  |  |  |  |  |  | $ 45,749 | $ 11,678
Maximum |  |  |  |  |  |  |  |
Lessee Lease Description [Line Items] |  |  |  |  |  |  |  |
Tenant improvement allowances yet to receive |  |  | $ 25,200 |  |  |  |  |
Letter of Credit |  |  |  |  |  |  |  |
Lessee Lease Description [Line Items] |  |  |  |  |  |  |  |
Security deposit |  |  |  |  |  |  |  | $ 1,600
Third amendment |  |  |  |  |  |  |  |
Lessee Lease Description [Line Items] |  |  |  |  |  |  |  |
Operating lease, description |  |  |  |  |  |  | The lease amendment for this additional space commenced in April 2021 and expires in March 2024. |
Lease expiration month and year |  |  |  | 2024-03 |  |  |  |
Initial Lease Agreement |  |  |  |  |  |  |  |
Lessee Lease Description [Line Items] |  |  |  |  |  |  |  |
Operating lease, existence of option to extend |  | true |  |  | true |  |  |
Lease term |  |  |  |  | 8 years |  |  |
Lease expiration year |  | 2029 |  |  | 2029 |  |  |
Lessee option to extend description |  | The lease amendment of this additional space commenced in April 2022 and expires in January 2029. The lease amendment also includes this additional space in the Company’s option to extend the amended Initial Lease Agreement for an additional seven-year term. |  |  |  |  | The lease amendment also includes an extension of the lease term for the existing office and laboratory space beginning on May 1, 2020 and expiring in January 2029. The amendment to the Initial Lease Agreement also includes an option to extend the lease for an additional seven-year term. |
Second Amendment Of Additional Lease Agreement |  |  |  |  |  |  |  |
Lessee Lease Description [Line Items] |  |  |  |  |  |  |  |
Tenant improvement allowances yet to receive | $ 25,200 |  |  |  |  |  |  |
Additional tenant improvement allowances | $ 15,000 |  |  |  |  |  |  |
Corporate Office and Laboratory Space |  |  |  |  |  |  |  |
Lessee Lease Description [Line Items] |  |  |  |  |  |  |  |
Weighted-average remaining lease term |  |  |  |  |  |  | 10 years 9 months 18 days |
Lease expiration year |  |  |  |  |  | 2025 |  |
Corporate Office and Laboratory Space | Initial Lease Agreement |  |  |  |  |  |  |  |
Lessee Lease Description [Line Items] |  |  |  |  |  |  |  |
Renewal term |  |  |  |  | 7 years |  |  |
Operating lease, existence of option to extend |  |  |  |  |  | true |  |
Lessee option to extend description |  |  |  |  |  |  | In April 2019, the Company executed the first amendment to the Initial Lease Agreement for additional corporate space, laboratory space and manufacturing capabilities and an extension to the lease term through April 2026. |

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