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Income Taxes - Significant Components of Deferred Tax Assets (Details) - USD ($) $ in Thousands | Dec. 31, 2022 | Dec. 31, 2021
--- | --- | ---
Deferred tax assets: |  |
Net operating loss carry forwards | $ 36,732 | $ 33,767
Depreciation and amortization | 316 | 268
Research and development credits | 11,999 | 6,984
Share-based compensation | 3,552 | 2,245
Accrued expenses | 1,367 | 1,189
Lease liability | 19,062 | 2,616
Other, net | 35 | 34
Section 174 Capitalized R&D | 17,352 | 0
Total deferred tax assets | 90,415 | 47,103
Valuation allowance for deferred tax assets | (71,368) | (44,361)
Deferred tax assets, net of valuation allowance | 19,047 | 2,742
Deferred tax liabilities: |  |
Right-of-use asset | (18,089) | (2,471)
Depreciation and amortization | (958) | (271)
Net deferred tax assets | $ 0 | $ 0

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