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Income Taxes - Reconciliation on Income Taxes Amount Computed by Applying Statutory Federal Income Tax Rate to Net Loss (Details) - USD ($)
12 Months Ended
Dec. 31, 2022
Dec. 31, 2021
Income Tax Disclosure [Abstract]    
Income tax benefit at statutory rates $ (23,906,000) $ (18,076,000)
State income tax, net of federal benefit (1,566,000) (1,005,000)
Permanent items 1,891,000 592,000
Research and development credits (3,426,000) (1,661,000)
Other (0) (515,000)
Change in valuation allowance 27,007,000 20,665,000
Income tax expense $ 0 $ 0