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Income Taxes - Significant Components of Deferred Tax Assets (Details) - USD ($)
$ in Thousands
Dec. 31, 2022
Dec. 31, 2021
Deferred tax assets:    
Net operating loss carry forwards $ 36,732 $ 33,767
Depreciation and amortization 316 268
Research and development credits 11,999 6,984
Share-based compensation 3,552 2,245
Accrued expenses 1,367 1,189
Lease liability 19,062 2,616
Other, net 35 34
Section 174 Capitalized R&D 17,352 0
Total deferred tax assets 90,415 47,103
Valuation allowance for deferred tax assets (71,368) (44,361)
Deferred tax assets, net of valuation allowance 19,047 2,742
Deferred tax liabilities:    
Right-of-use asset (18,089) (2,471)
Depreciation and amortization (958) (271)
Net deferred tax assets $ 0 $ 0