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v3.23.2

CONDENSED STATEMENT OF CASH FLOWS (Unaudited) | 6 Months Ended
--- | ---
Jun. 30, 2023 USD ($) | Jun. 30, 2022 USD ($)
Cash flows from operating activities |  |
Net loss | $ (64,102,000) | $ (52,910,000)
Adjustments to reconcile net loss to net cash used in operating activities: |  |
Share-based compensation expense | 9,396,000 | 8,009,000
Depreciation and amortization | 1,636,000 | 1,243,000
Accretion and amortization of premiums and discounts on investments, net | (4,511,000) | 1,110,000
Realized gain on investments | (34,000) | 0
Impairment of right-of-use assets | 4,100,000 |
Non-cash lease expense | 1,100,000 | 2,019,000
Changes in operating assets and liabilities: |  |
Prepaid expenses and other assets | 663,000 | 3,282,000
Operating lease liabilities | 7,143,000 | 3,649,000
Accounts payable and accrued and other liabilities | 2,078,000 | (1,274,000)
Net cash used in operating activities | (42,531,000) | (34,872,000)
Cash flows from investing activities |  |
Purchases of property and equipment | (15,151,000) | (4,399,000)
Purchases of investments | (157,486,000) | (175,011,000)
Maturities of investments | 206,395,000 | 69,088,000
Net cash provided by (used in) investing activities | 33,758,000 | (110,322,000)
Cash flows from financing activities |  |
Proceeds from stock option exercises | 22,000 | 413,000
Proceeds from ESPP purchases | 374,000 |
Proceeds from secondary offering, net of issuance costs |  | 215,611,000
Net cash provided by financing activities | 396,000 | 216,024,000
Net (decrease) increase in cash and cash equivalents | (8,377,000) | 70,830,000
Cash, cash equivalents, and restricted cash beginning of period | 40,237,000 | 62,914,000
Cash, cash equivalents, and restricted cash end of period | 31,860,000 | 133,744,000
Reconciliation of cash, cash equivalents and restricted cash to the balance sheet: |  |
Cash and cash equivalents | 29,117,000 | 131,646,000
Restricted cash | 2,743,000 | 2,098,000
Total cash, cash equivalents and restricted cash | 31,860,000 | 133,744,000
Supplemental disclosures of non-cash investing activities: |  |
Acquisitions of property and equipment in accounts payable | $ 690,000 | $ 926,000

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