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v3.25.2

Segment Reporting - Summary of Reconciliation to Net Loss (Details) - USD ($) $ in Thousands | 3 Months Ended | 6 Months Ended
--- | --- | ---
Jun. 30, 2025 | Mar. 31, 2025 | Jun. 30, 2024 | Mar. 31, 2024 | Jun. 30, 2025 | Jun. 30, 2024
Segment expenses: |  |  |  |  |  |  |
Total operating expenses |  | $ 27,186 |  | $ 30,715 |  | $ 63,750 | $ 63,477
Net loss |  | (22,977) | $ (31,983) | (24,993) | $ (29,518) | (54,960) | (54,511)
Reconciling items: |  |  |  |  |  |  |
Depreciation and amortization |  | (2,331) |  | (2,262) |  | (4,630) | (4,517)
Share-based compensation |  | (2,053) |  | (4,414) |  | (4,887) | (8,782)
Interest income |  | 3,970 |  | 5,724 |  | 8,346 | 8,970
Other income (expense), net |  | 239 |  | (2) |  | 444 | (4)
Segment |  |  |  |  |  |  |
Segment expenses: |  |  |  |  |  |  |
Personnel related expenses, excluding share-based compensation | [1] | 7,718 |  | 9,921 |  | 23,615 | 20,409
Facilities expenses |  | 4,771 |  | 4,706 |  | 9,336 | 9,352
Direct external development program expenses |  | 4,850 |  | 4,475 |  | 10,270 | 11,068
Other segment expenses | [2] | 5,463 |  | 4,937 |  | 11,012 | 9,349
Total operating expenses |  | 22,802 |  | 24,039 |  | 54,233 | 50,178
Net loss |  | $ (22,802) |  | $ (24,039) |  | $ (54,233) | $ (50,178)
[1] | Personnel related expenses include ($0.1) million and $5.0 million of severance and other benefits expense for the three and six months ended June 30, 2025, respectively.
[2] | Other segment items include consultants and contractor, lab supplies, and general business expenses.

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