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v3.25.2

Segment Reporting (Tables) | 6 Months Ended
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Jun. 30, 2025
Segment Reporting [Abstract] |
Summary of Reconciliation to Net Loss | A reconciliation to the net loss for the three and six months ended June 30, 2025 and 2024 is included at the bottom of the table below.
|  | Three Months Ended June 30, |  |  | Six Months Ended June 30, |
|  | 2025 |  |  | 2024 |  |  | 2025 |  |  | 2024 |
Segment expenses: |  |  |  |  |  |  |  |  |  |  |  |
Personnel related expenses, excluding share-based compensation(1) |  |  | 7,718 |  |  |  | 9,921 |  |  | $ | 23,615 |  |  | $ | 20,409 |
Facilities expenses |  |  | 4,771 |  |  |  | 4,706 |  |  |  | 9,336 |  |  |  | 9,352 |
Direct external development program expenses |  |  | 4,850 |  |  |  | 4,475 |  |  |  | 10,270 |  |  |  | 11,068 |
Other segment expenses (2) |  |  | 5,463 |  |  |  | 4,937 |  |  |  | 11,012 |  |  |  | 9,349 |
Total segment expenses: |  |  | 22,802 |  |  |  | 24,039 |  |  |  | 54,233 |  |  |  | 50,178 |
Segment loss |  |  | (22,802 | ) |  |  | (24,039 | ) |  |  | (54,233 | ) |  |  | (50,178 | )
Reconciling items: |  |  |  |  |  |  |  |  |  |  |  |
Depreciation and amortization |  |  | (2,331 | ) |  |  | (2,262 | ) |  |  | (4,630 | ) |  |  | (4,517 | )
Share-based compensation |  |  | (2,053 | ) |  |  | (4,414 | ) |  |  | (4,887 | ) |  |  | (8,782 | )
Interest income |  |  | 3,970 |  |  |  | 5,724 |  |  |  | 8,346 |  |  |  | 8,970 |
Other income (expense), net |  |  | 239 |  |  |  | (2 | ) |  |  | 444 |  |  |  | (4 | )
Net loss |  | $ | (22,977 | ) |  | $ | (24,993 | ) |  | $ | (54,960 | ) |  | $ | (54,511 | )
(1) Personnel related expenses include ($0.1) million and $5.0 million of severance and other benefits expense for the three and six months ended June 30, 2025, respectively. (2) Other segment items include consultants and contractor, lab supplies, and general business expenses.

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- Definition Tabular disclosure of the reconciliation of profit (loss) from reportable segments to the consolidated income (loss) before income tax expense (benefit) and discontinued operations. Includes, but is not limited to, reconciliation after income tax if income tax is allocated to the reportable segment. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Name Accounting Standards Codification -Topic 280 -SubTopic 10 -Section 50 -Paragraph 31 -Publisher FASB -URI https://asc.fasb.org/1943274/2147482810/280-10-50-31 Reference 2: http://fasb.org/us-gaap/role/ref/legacyRef -Name Accounting Standards Codification -Topic 280 -SubTopic 10 -Section 50 -Paragraph 30 -Subparagraph (b) -Publisher FASB -URI https://asc.fasb.org/1943274/2147482810/280-10-50-30 + Details
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